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Recent Patents on Anti-Cancer Drug Discovery

Volume 14, 4 Issues, 2019
ISSN: 2212-3970 (Online)
ISSN: 1574-8928 (Print)
This journal supports open access

Aims & Scope

Recent Patents on Anti-Cancer Drug Discovery publishes review and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of anti-cancer drug discovery e.g. on novel bioactive compounds, analogs, targets & predictive biomarkers & drug efficacy biomarkers. The journal also publishes book reviews of eBooks and books on anti-cancer drug discovery. A selection of important and recent patents on anti-cancer drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-cancer drug design and discovery. The journal also covers recent research (where patents have been registered) in fast emerging therapeutic areas/targets & therapeutic agents related to anti-cancer drug discovery.

Recent Patents on Anti-Cancer Drug Discovery

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Volume 13

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Number 4



Biography   Open Access



Review Article

PARP Inhibitors in Ovarian Cancer

, 13(4): 392 - 410

Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*


DOI: 10.2174/1574892813666180305165256


Review Article

Journey Describing the Cytotoxic Potential of Withanolides: A Patent Review

, 13(4): 411 - 421

Hidayat Hussain*, Rene Csuk, Ivan R. Green, Najeeb Ur Rehman, Ghulam Abbas and Wahid Hussain


DOI: 10.2174/1574892813666180808154928


Review Article   Open Access



Review Article   Open Access



Review Article

Recent Progress of Marine Polypeptides as Anticancer Agents

, 13(4): 445 - 454

Lanhong Zheng, Yixin Xu, Xiukun Lin*, Zhixin Yuan, Minghua Liu, Shousong Cao, Fuming Zhang and Robert J. Linhardt


DOI: 10.2174/1574892813666180430110033


Review Article



Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency

, 13(4): 469 - 472

Georgy Y. Nadysev, Alexander S. Tikhomirov, Lyubov G. Dezhenkova and Andrey E. Shchekotikhin*


DOI: 10.2174/1574892813666180723150542


Recent Patents on Anti-Cancer Drug Discovery, Volume 14 (2019) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Abstracts Ahead of Print

Enzyme and Transporter Kinetics for CPT-11 (Irinotecan) and SN-38: An Insight on Tumor Tissue Compartment Pharmacokinetics Using PBPK


Yingfang Fan, Najia Mansoor*, Tasneem Ahmad, Zhuo X. Wu, Rafeeq A. Khan, Martin Czejka, Syed Sharib, Mansoor Ahmed, Zhe S. Chen and Dong H. Yang*


View Abstract


Editor's Choice

PARP Inhibitors in Ovarian Cancer

, 2018; 13(4): 392 - 410

Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*


DOI: 10.2174/1574892813666180305165256







Pharmacological Inhibitors of NAD Biosynthesis as Potential An ticancer Agents

, 2017; 12(3): 190 - 207

Stephanie Lucas, Claire Soave, Ghazal Nabil, Zainab Sabry Othman Ahmed, Guohua Chen, Hossny Awad El-Banna, Q. Ping Dou* and Jian Wang*


DOI: 10.2174/1574892812666170619125503





Docking and QSAR Studies of 1,4-Dihydropyridine Derivatives as Anti- Cancer Agent

, 2017; 12(2): 174 - 185

Shirin Mollazadeh, Jamal Shamsara, Maryam Iman* and Farzin Hadizadeh*


DOI: 10.2174/1574892812666170126162521



Kinase Inhibitor Indole Derivatives as Anticancer Agents: A Patent Review

, 2017; 12(1): 55 - 72

Anuj K. Rathi, Riyaz Syed, Vijay Singh, Han-Seung Shin and Rahul V. Patel


DOI: 10.2174/1574892811666161003112119



Open Access Articles

Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency

, 2018; 13(4): 469 - 472

Georgy Y. Nadysev, Alexander S. Tikhomirov, Lyubov G. Dezhenkova and Andrey E. Shchekotikhin*





Targeting Metabolism to Counteract Tumor Angiogenesis: A Review of Patent Literature

, 2018; 13(4): 422 - 427

Sara Petrillo, Emanuela Tolosano, Luca Munaron and Tullio Genova*




Anaplastic Lymphoma Kinase in Glioblastoma: Detection/Diagnostic Methods and Therapeutic Options

, 2018; 13(2): 209 - 223

Theodosis Kalamatianos, Despoina Denekou, George Stranjalis and Evangelia Papadimitriou*




Lenvatinib in the Therapy of Aggressive Thyroid Cancer: State of the Art and New Perspectives with Patents Recently Applied

, 2018; 13(2): 201 - 208

Silvia M. Ferrari, Ilaria Ruffilli, Marco Centanni, Camilla Virili, Gabriele Materazzi, Magdalini Alexopoulou, Mario Miccoli, Alessandro Antonelli* and Poupak Fallahi




Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins

, 2018; 13(2): 184 - 200

Federica Iannelli, Rita Lombardi, Maria R. Milone, Biagio Pucci, Simona De Rienzo, Alfredo Budillon* and Francesca Bruzzese*




PARP Inhibitors in Epithelial Ovarian Cancer

, 2018; 13(2): 145 - 158

Kristin N. Taylor and Ramez N. Eskander*





Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy

, 2018; 13(1): 86 - 105

Marco L. Lolli, Stefano Sainas, Agnese C. Pippione, Marta Giorgis, Donatella Boschi and Franco Dosio*




Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy

, 2018; 13(1): 2 - 17

Sandra Iurescia*, Daniela Fioretti and Monica Rinaldi*




Strategies to Tackle Radiation Resistance by Penetrating Cancer Stem Cell Line of Scrimmage

, 2018; 13(1): 18 - 39

So-Yeon Park, Ji-Young Kim, Youngsoo Jun and Jeong-Seok Nam*







Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment

, 2016; 11(2): 184 - 196

Li Huang, Rongzhang He, Weihao Luo, Yuan-Shan Zhu, Jia Li, Tan Tan, Xi Zhang, Zheng Hu and Dixian Luo





Most Cited Articles

Multi-Targeted Agents in Cancer Cell Chemosensitization: What We Learnt from Curcumin Thus Far

, 2016; 11(1): 67-97.

Devivasha Bordoloi, Nand K. Roy, Javadi Monisha, Ganesan Padmavathi and Ajaikumar B. Kunnumakkara


DOI: 10.2174/1574892810666151020101706


Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment

, 2016; 11(2): 184-196.

Li Huang, Rongzhang He, Weihao Luo, Yuan-Shan Zhu, Jia Li, Tan Tan, Xi Zhang, Zheng Hu and Dixian Luo


DOI: 10.2174/1574892811888160304113346



Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In vivo, In vitro and Network Analyses

, 2016; 11(1): 121-133.

Amr Amin, Alaaeldin A. Hamza, Sayel Daoud, Kamal Khazanehdari, Ala’a Al Hrout, Badriya Baig, Amphun Chaiboonchoe, Thomas E. Adrian, Nazar Zaki and Kourosh Salehi-Ashtiani


DOI: 10.2174/1574892810666151102110248


Decreased Expression of Caveolin-1 and E-Cadherin Correlates with the Clinicopathologic Features of Gastric Cancer and the EMT Process

, 2016; 11(2): 236-244.

Kundong Zhang, Guang Yang, Weidong Wu, Jing Zhang, Xiang Xia, Tao Jiang, Jun Cao, Kejan Huang, Zhengjun Qiu and Chen Huang


DOI: 10.2174/1574892811666160128151437




Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells

, 2016; 11(2): 215-227.

Yanming Wang, Jun Ma, Xinyan Yan, Xiaoyu Chen, Lingling Si, Ying Liu, Jichun Han, Wenjin Hao and Qiusheng Zheng


DOI: 10.2174/1573406412666160307151904


Epigenetics in Medullary Thyroid Cancer: From Pathogenesis to Targeted Therapy

, 2016; 11(3): 275-282.

Giovanni Vitale, Alessandra Dicitore, Erika Messina, Concetta Sciammarella, Antongiulio Faggiano and Annamaria Colao


DOI: 10.2174/1574892811666160614115356


Anti-EGFR Therapy: Strategies in Head and Neck Squamous Cell Carcinoma

, 2016; 11(2): 170-183.

Renato J. Oliveira-Silva, Ana Carolina de Carvalho, Luciano de Souza Viana, Andre L. Carvalho and Rui M. Reis


DOI: 10.2174/1574892811666160309121238



Most Accessed Articles

Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy

, 2018; 13(1): 86-105.

Marco L. Lolli, Stefano Sainas, Agnese C. Pippione, Marta Giorgis, Donatella Boschi and Franco Dosio*


DOI: 10.2174/1574892812666171108124218




PARP Inhibitors in Ovarian Cancer

, 2018; 13(4): 392-410.

Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*


DOI: 10.2174/1574892813666180305165256


Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins

, 2018; 13(2): 184-200.

Federica Iannelli, Rita Lombardi, Maria R. Milone, Biagio Pucci, Simona De Rienzo, Alfredo Budillon* and Francesca Bruzzese*


DOI: 10.2174/1574892812666171129141211





Breast Cancer: Current Developments in Molecular Approaches to Diagnosis and Treatment

, 2014; 9(2): 153-175.

Jo-Anne de la Mare, Lara Contu, Morgan C. Hunter, Buhle Moyo, Jason N. Sterrenberg, Karim C.H. Dhanani, Lorraine Z. Mutsvunguma and Adrienne L. Edkins


DOI: 10.2174/15748928113086660046




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