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Protein & Peptide Letters

Volume 28, 12 Issues, 2021
ISSN: 1875-5305 (Online)
ISSN: 0929-8665 (Print)
This journal supports open access

Aims & Scope

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations.

Protein & Peptide Letters focuses on:


  • Structure Studies
  • Advances in Recombinant Expression
  • Drug Design
  • Chemical Synthesis
  • Function
  • Pharmacology
  • Enzymology
  • Conformational Analysis
  • Immunology
  • Biotechnology
  • Protein Engineering
  • Protein Folding
  • Sequencing
  • Molecular Recognition
  • Purification and Analysis

Protein & Peptide Letters

,

Volume 28

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Number 9



Letter Article

Nonhuman IAPP Variants Inhibit Human IAPP Aggregation

, 28(9): 963 - 971

Alissa Oakes, Kate Menefee, Arleen Lamba, Larry M. Palato, Dillon J. Rinauro, Angela Tun, Betssy Jauregui, Kevin Chang, Luiza A. Nogaj and David A. Moffet*


DOI: 10.2174/0929866528666210806152706


Review Article (Mini-Review)

Database Study on the Expression and Purification of Membrane Proteins

, 28(9): 972 - 982

Chen-Yan Zhang *, Shi-Qi Zhao , Shi-Long Zhang , Li-Heng Luo, Ding-Chang Liu, Wei-Hang Ding, Dong-Jie Fu, Xu-Dong Deng and Da-Chuan Yin *


DOI: 10.2174/0929866528666210415120234


Review Article (Mini-Review)









Research Article

Fusion Expression and Fibrinolytic Activity of rPA/SP-B

, 28(9): 1033 - 1042

Yi-Shan Tang, Xiao-Jun Zhang, Wan-Neng Wang*, Ting Wang, Wu-Long Cao, Qiu-Han Zhang and Fu Chen


DOI: 10.2174/0929866528666210301151302




Abstracts Ahead of Print








Oral angiotensin-(1–7) peptide modulates intestinal microbiota improving metabolic profile in obese mice


Amanda S Machado, Janaína R Oliveira, Deborah de F Lelis, Victor Hugo D Guimarães, Alfredo M B de Paula, André L S Guimarães, Igor V Brandi, Bruna Mara A de Carvalho, Diego Vicente da Costa, Cláudia Regina Vieira, Ulisses Alves Pereira, Theles de Oliveira Costa, João M O Andrade, Robson A S dos Santos and Sérgio H S Santos*


DOI: 10.2174/0929866528666210816115645
View Abstract


An Intracellular Tripeptide Arg-His-Trp of Serum Origin Detected in MCF-7 Cells Is A Possible Agonist to β2 Adrenoceptor


Hritik Chandore, Ajay Kumar Raj, Kiran Bharat Lokhande, K. Venkateswara Swamy, Jayanta K. Pal and Nilesh Kumar Sharma*


DOI: 10.2174/0929866528666210816114901
View Abstract



Published Contents

Editor's Choice

Nonhuman IAPP Variants Inhibit Human IAPP Aggregation

, 2021; 28(9): 963 - 971

Alissa Oakes, Kate Menefee, Arleen Lamba, Larry M. Palato, Dillon J. Rinauro, Angela Tun, Betssy Jauregui, Kevin Chang, Luiza A. Nogaj and David A. Moffet*


DOI: 10.2174/0929866528666210806152706



Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19

, 2021; 28(8): 945 - 952

Amir Hossein Kheirkhah, Seyed Hossein Shahcheraghi, Malihe lotfi, Marzieh lotfi*, Sanaz Raeisi and Zulfiqar Mirani*


DOI: 10.2174/0929866528666210222150347



Hydroalcoholic Extract of Solanum lycocarpum A. St. Hil. (Solanaceae) Leaves Improves Alloxan-Induced Diabetes Complications in Mice

, 2021; 28(7): 769 - 780

Victor Hugo Dantas Guimarães, Jéssica Nayara Basilio Silva, Daniela Fernanda de Freitas, Otávio Cardoso Filho, Luiz Henrique da Silveira, Barbhara Mota Marinho, Alfredo Maurício Batista de Paula, Geraldo Aclécio Melo and Sérgio Henrique Sousa Santos*


DOI: 10.2174/0929866528999210128205817



Plant Bioactive Peptides: Current Status and Prospects Towards Use on Human Health

, 2021; 28(6): 623 - 642

Tsun-Thai Chai*, Kah-Yaw Ee, D. Thirumal Kumar, Fazilah Abd Manan and Fai-Chu Wong


DOI: 10.2174/0929866527999201211195936





Phosphorylated and O-GlcNAc Modified IRS-1 (Ser1101) and -2 (Ser1149) Contribute to Human Diabetes Type II

, 2021; 28(3): 333 - 339

Afshan Kaleem*, Sabahat Javed, Nayab Rehman, Roheena Abdullah, Mehwish Iqtedar, Mohammad Nauman Aftab, Daniel C. Hoessli and Ikram-Ul Haq


DOI: 10.2174/0929866527666200813210407




Expression, Solubilization, Refolding and Final Purification of Recombinant Proteins as Expressed in the form of “Classical Inclusion Bodies” in E. coli

, 2021; 28(2): 122 - 130

Mohammad Sadegh Hashemzadeh*, Mozafar Mohammadi, Hadi Esmaeili Gouvarchin Ghaleh, Mojtaba Sharti, Ali Choopani and Amulya Kumar Panda


DOI: 10.2174/0929866527999200729182831



Establishment of Method for the Determination of Aggregated α-Synuclein in DLB Patient Using RT-QuIC Assay

, 2021; 28(1): 115 - 120

Seok-Joo Park, Yun-Jung Lee, Jeong-Ho Park, Hyoung-Tae Jin, Myoung-Ju Choi, Cha-Gyun Jung, Hiroyasu Akatsu, Eun-Kyoung Choi and Yong-Sun Kim*


DOI: 10.2174/0929866527666200420105352



Open Access Articles

Assessment of Proteolysis by Pyrylium and Other Fluorogenic Reagents

, 2021; 28(7): 809 - 816

Mohamed K. Al-Essa*, Ebaa Alzayadneh and Kamal Al-Hadidi





Expression, Purification and Characterization of Recombinant Human Coagulation Factor XIIIa in Pichia Pastoris

, 2021; 28(1): 55 - 62

Linyan Cheng, Ting Zhang, Yuchang Fei, Hao Shen, Hui Huang, Jin Chen, Bin Xu* and Jian Xu*




Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?

, 2020; 27(12): 1186 - 1191

Giuseppe Grande*, Domenico Milardi, Silvia Baroni, Andrea Urbani and Alfredo Pontecorvi




The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence

, 2020; 27(6): 463 - 475

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*




miR-146a-5p Regulated Cell Proliferation and Apoptosis by Targeting SMAD3 and SMAD4

, 2020; 27(5): 411 - 418

Meiyu Qiu, Tao Li, Binhu Wang, Hongbin Gong and Tao Huang*





NMAAP1 Maintains M1 Phenotype in Macrophages Through Binding to IP3R and Activating Calcium-related Signaling Pathways

, 2019; 26(10): 751 - 757

Qihui Liu, Pei Zhu, Shanshan Liu, Mengyan Tang, Yuanxin Wang, Yuan Tian, Zheng Jin, Dong Li and Dongmei Yan*






Differential S-acylation of Enveloped Viruses

, 2019; 26(8): 588 - 600

Larisa V. Kordyukova*, Marina V. Serebryakova, Vladislav V. Khrustalev and Michael Veit





Little Antimicrobial Peptides with Big Therapeutic Roles

, 2019; 26(8): 564 - 578

Dan Zhang, Yu He, Yang Ye, Yanni Ma, Peng Zhang, Hongxia Zhu, Ningzhi Xu and Shufang Liang*





Dimerization of Antimicrobial Peptides: A Promising Strategy to Enhance Antimicrobial Peptide Activity

, 2019; 26(2): 98 - 107

Esteban N. Lorenzon, Julia P. Piccoli, Norival A. Santos-Filho and Eduardo M. Cilli*





Most Cited Articles


Review Article (Mini-Review)

Mini review on antimicrobial peptides, sources, mechanism and recent applications

, 2020; 27(1): 4-16.

Jaspreet Kaur Boparai and Pushpender Kumar Sharma*


DOI: 10.2174/0929866526666190822165812



Review Article

Clinical applications of antimicrobial peptides (AMPs): Where do we stand now?

, 2020; 27(2): 120-134.

Mithoor Divyashree, Madhu K. Mani, Dhanasekhar Reddy, Ranjith Kumavath*, Preetam Ghosh, Vasco Azevedo and Debmalya Barh*


DOI: 10.2174/0929866526666190925152957



Review Article

Leucine rich repeat proteins: Sequences, mutations, structures and diseases

, 2019; 26(2): 108-131.

Norio Matsushima*, Shintaro Takatsuka, Hiroki Miyashita and Robert H. Kretsinger


DOI: 10.2174/0929866526666181208170027


Research Article

Characterizing the binding of angiotensin converting enzyme i inhibitory peptide to human hemoglobin: Influence of electromagnetic fields

, 2020; 27(10): 1007-1021.

Farzaneh Sadeghzadeh, Amir Arsalan Entezari, Kiana Behzadian, Kimia Habibi, Zeinab Amiri-Tehranizadeh*, Ahmad Asoodeh, Mohammad Reza Saberi and Jamshidkhan Chamani*


DOI: 10.2174/1871530320666200425203636


Review Article

Dimerization of antimicrobial peptides: A promising strategy to enhance antimicrobial peptide activity

, 2019; 26(2): 98-107.

Esteban N. Lorenzon, Julia P. Piccoli, Norival A. Santos-Filho and Eduardo M. Cilli*


DOI: 10.2174/0929866526666190102125304


Research Article

Lytic polysaccharide monooxygenase from aspergillus fumigatus can improve enzymatic cocktail activity during sugarcane bagasse hydrolysis

, 2019; 26(5): 377-385.

Paula Fagundes de Gouvêa, Luis Eduardo Gerolamo, Aline Vianna Bernardi, Lucas Matheus Soares Pereira, Sergio Akira Uyemura and Taisa Magnani Dinamarco*


DOI: 10.2174/0929866526666190228163629


Research Article

Applicability of instability index for in vitro protein stability prediction

, 2019; 26(5): 339-347.

Dilani G. Gamage, Ajith Gunaratne, Gopal R. Periyannan* and Timothy G. Russell


DOI: 10.2174/0929866526666190228144219


Review Article

The renin-angiotensin system and the cerebrovascular diseases: Experimental and clinical evidence

, 2020; 27(6): 463-475.

Lucas M. Kangussu, Lucas Alexandre Santos Marzano, Cássio Ferraz Souza, Carolina Couy Dantas, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929866527666191218091823



Research Article

Influence of calcium ions on the thermal characteristics of α-amylase from thermophilic anoxybacillus sp. gxs-bl

, 2019; 26(2): 148-157.

Si-Ming Liao , Ge Liang , Jing Zhu , Bo Lu , Li-Xin Peng , Qing-Yan Wang, Yu-Tuo Wei , Guo-Ping Zhou* and Ri-Bo Huang *


DOI: 10.2174/0929866526666190116162958



Research Article

Chickpea (Cicer arietinum L.) lectin exhibit inhibition of ACE-I, α-amylase and α-glucosidase activity

, 2019; 26(7): 494-501.

Sameer Suresh Bhagyawant*, Dakshita Tanaji Narvekar, Neha Gupta, Amita Bhadkaria, Ajay Kumar Gautam and Nidhi Srivastava


DOI: 10.2174/0929866526666190327130037



Most Accessed Articles




Fusion Expression and Fibrinolytic Activity of rPA/SP-B

, 2021; 28(9): 1033-1042.

Yi-Shan Tang, Xiao-Jun Zhang, Wan-Neng Wang*, Ting Wang, Wu-Long Cao, Qiu-Han Zhang and Fu Chen


DOI: 10.2174/0929866528666210301151302





Strategy for the Enrichment of Protein Biomarkers from Diverse Bacterial Select Agents

, 2021; 28(9): 1071-1082.

Sasikumar Sabna, Dev Vrat Kamboj, Ravi Bhushan Kumar, Prabhakar Babele, Sakshi Rajoria, Mahendra Kumar Gupta and Syed Imteyaz Alam*


DOI: 10.2174/0929866528666210405160131



Mesenchymal Stem Cell Derived-Exosomes as Effective Factors in Reducing Cytokine Storm Symptoms of COVID-19

, 2021; 28(8): 945-952.

Amir Hossein Kheirkhah, Seyed Hossein Shahcheraghi, Malihe lotfi, Marzieh lotfi*, Sanaz Raeisi and Zulfiqar Mirani*


DOI: 10.2174/0929866528666210222150347




Genome-Wide Association Studies (GWAS) for Traits Related to Fodder Quality and Biofuel in Sorghum: Progress and Prospects

, 2021; 28(8): 843-854.

Vinutha Kanuganahalli Somegowda, Laavanya Rayaprolu, Abhishek Rathore, Santosh Pandurang Deshpande* and Rajeev Gupta*


DOI: 10.2174/0929866528666210127153103


Genome-Wide Association Study for Major Biofuel Traits in Sorghum Using Minicore Collection

, 2021; 28(8): 909-928.

Laavanya Rayaprolu, Sivasubramani Selvanayagam, D. Manohar Rao, Rajeev Gupta, Roma Rani Das, Abhishek Rathore, Prasad Gandham, K.N.S. Usha Kiranmayee, Santosh P. Deshpande* and Ashok Kumar Are*


DOI: 10.2174/0929866528666210215141243


Database Study on the Expression and Purification of Membrane Proteins

, 2021; 28(9): 972-982.

Chen-Yan china Zhang *, Shi-Qi Zhao , Shi-Long Zhang , Li-Heng Luo, Ding-Chang Liu, Wei-Hang Ding, Dong-Jie Fu, Xu-Dong Deng and Da-Chuan Yin *


DOI: 10.2174/0929866528666210415120234




Editor-in-Chief

graphic
Prof. Ben M. Dunn
Department of Biochemistry and Molecular Biology
University of Florida
College of Medicine
Gainesville, FL
(USA)
Email: bdunn@ufl.eduBiography
View Full Editorial Board

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Journal History

Protein & Peptide Letters was introduced in 2001 with the assistance of Dr. Ben M. Dunn, who is the current Editor-in-Chief serving since 2001.
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