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Current Molecular Pharmacology

Volume 14, 6 Issues, 2021
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 14

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Number 2







Review Article (Mini-Review)





Review Article (Mini-Review)









Articles Ahead of Print

Organoids: Current Implications and Pharmaceutical Applications in Liver Diseases


Mengqi Zhu, Yuting Huang, Saiyan Bian, Qianqian Song, Jie Zhang, Wenjie Zheng* and Chun Cheng*


DOI: 10.2174/1874467213666201217115854
View Abstract View on PubMed






Water pipe tobacco smoking and risk of Coronary Artery Disease: A systematic review and meta-analyses


Negar Morovatdar, Hoorak Poorzand, Yones Bondarsahebi, Seyyed Amin Hozhabrossadati, Sanaollah Montazeri* and Amirhossein Sahebkar*


DOI: 10.2174/1874467213666201223121322
View Abstract View on PubMed


MicroRNA Regulation of TRAIL in Renal Carcinoma: Tiny Juggernauts at Work


Zeeshan Javed, Khushbukhat Khan, Haleema Sadia, Shahid Raza, Javad Sharifi-Rad* and William C. Cho*


DOI: 10.2174/1874467213999201124124649
View Abstract View on PubMed



Polyphenols as Potential Therapeutics for Pain and Inflammation in Spinal Cord Injury


Ashif Iqubal, Musheer Ahmed, Mohammad Kashif Iqubal, Faheem Hyder Pottoo and Syed Ehtaishamul Haque*


DOI: 10.2174/1874467213666201223111743
View Abstract View on PubMed


Quercetin in Attenuation of Ischemic/Reperfusion Injury: A Review


Milad Ashrafizadeh, Saeed Samarghandian, Kiavash Hushmandi, Amirhossein Zabolian, Md Shahinozzaman, Hossein Saleki, Hossein Esmaeili, Mehdi Raei, Maliheh Entezari, Ali Zarrabi* and Masoud Najafi*


DOI: 10.2174/1874467213666201217122544
View Abstract View on PubMed


Abstracts Ahead of Print



Assessment of Antioxidant Effect of Beta-Glucan on the Whole Blood Oxidative DNA Damage with the Comet Assay in Colorectal Cancer


Necla Benlier, Nilay Uçar, Eda Öğüt, Havva Yeşil Çinkir, Mustafa Yildirim, Pınar Günel Karadeniz, Esra Küpeli Akkol*, Haroon Khan and Eyüp Ilker Saygili*


DOI: 10.2174/1874467214666210219145445
View Abstract


Inhibitory Effects of Cathepsin K Inhibitor (ODN-MK-0822) on the Paracrine Pro-Osteoclast Factors of Breast Cancer Cells


Yaongamphi Vashum, Amuthavalli Kottaiswamy, Giridharan Bupesh, Riya Prem Singh, Parkavi Kalaiselvan, Thiagarajan K and Shila Samuel*


DOI: 10.2174/1874467214666210211162118
View Abstract




Statins Attenuate Fibrotic Manifestations of Cardiac Tissue Damage


Armita Mahdavi Gorabi, Nasim Kiaie, Vanessa Bianconi, Matteo Pirro, Tannaz Jamialahmadi and Amirhossein Sahebkar*


DOI: 10.2174/1874467214666210210123206
View Abstract





Published Contents

Editor's Choice

TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy

, 2021; 14(2): 123 - 131

Kazuhiro Nishiyama, Tomohiro Tanaka, Akiyuki Nishimura and Motohiro Nishida*


DOI: 10.2174/1874467213666200407090121



Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis

, 2021; 14(2): 165 - 169

Yoshifumi Takahata*, Tomohiko Murakami, Kenji Hata and Riko Nishimura


DOI: 10.2174/1874467213666200417122933




Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma

, 2020; 13(4): 261 - 272

Mengna Wu, Huajie Miao, Rong Fu, Jie Zhang* and Wenjie Zheng *


DOI: 10.2174/1874467213666200224102820




Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

, 2020; 13(3): 216 - 223

Tatiana V. Vyunova*, Lioudmila A. Andreeva, Konstantin V. Shevchenko, Vladimir V. Grigoriev, Vladimir A. Palyulin, Mstislav I. Lavrov, Ekaterina V. Bondarenko, Elena E. Kalashnikova and Nikolay F. Myasoedov


DOI: 10.2174/1874467213666200303140834



Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis

, 2020; 13(2): 150 - 172

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935






Open Access Articles

Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats

, 2021; 14(2): 245 - 252

Nobuo Izumo*, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*




Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway

, 2021; 14(1): 101 - 111

Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao* and Shilin Yang




New Insights in Cannabinoid Receptor Structure and Signaling

, 2019; 12(3): 239 - 248

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*





Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*




Mitochondria-Targeted Drugs

, 2019; 12(3): 202 - 214

Roman A. Zinovkin* and Andrey A. Zamyatnin*




A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia

, 2019; 12(3): 195 - 201

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar




Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions

, 2019; 12(3): 184 - 194

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva




Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures

, 2017; 10(4): 334 - 344

Andrew S. Dore, Andrea Bortolato, Kaspar Hollenstein, Robert K.Y. Cheng, Randy J. Read and Fiona H. Marshall*






Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

, 2015; 8(2): 110 - 122

Jorg Striessnig, Nadine J. Ortner and Alexandra Pinggera






Most Cited Articles

Research Article

Mir-4319 suppresses the growth of esophageal squamous cell carcinoma via targeting NLRC5

, 2020; 13(2): 144-149.

Xiao Hu, Min Wang, Lei Cao, Li Cong, Yujie Gao, Jianwei Lu, Jifeng Feng, Bo Shen and Delin Liu*


DOI: 10.2174/1874467212666191119094636


Review Article

Recent updates in the alzheimer’s disease etiopathology and possible treatment approaches: A narrative review of current clinical trials

, 2020; 13(4): 273-294.

Elahe Zarini-Gakiye, Javad Amini, Nima Sanadgol*, Gholamhassan Vaezi and Kazem Parivar


DOI: 10.2174/1874467213666200422090135



Review Article

Hepatic stellate cell: A potential target for hepatocellular carcinoma

, 2020; 13(4): 261-272.

Mengna Wu, Huajie Miao, Rong Fu, Jie Zhang* and Wenjie Zheng *


DOI: 10.2174/1874467213666200224102820


Review Article

Therapeutic promises of chlorogenic acid with special emphasis on its anti-obesity property

, 2020; 13(1): 7-16.

Rajnish Kumar, Anju Sharma, Mohammed Shariq Iqbal and Janmejai K. Srivastava*


DOI: 10.2174/1874467212666190716145210



Research Article

Discovering therapeutic protein targets for bladder cancer using proteomic data analysis

, 2020; 13(2): 150-172.

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935


Review Article

2-aminoethyldiphenyl borinate: A multitarget compound with potential as a drug precursor

, 2020; 13(1): 57-75.

Melvin N. Rosalez, Elizabeth Estevez-Fregoso, Alberto Alatorre, Antonio Abad-García* and Marvin A. Soriano-Ursúa*


DOI: 10.2174/1874467212666191025145429


Review Article

The role of autophagy in cancer radiotherapy

, 2020; 13(1): 31-40.

Lei Li, Wen-Ling Liu, Lei Su, Zhou-Cheng Lu and Xiu-Sheng He*


DOI: 10.2174/1874467212666190809154518


Research Article

Evaluation of the effects of 1,25 vitamin d3 on regulatory t cells and t helper 17 cells in vitamin d-deficient women with unexplained recurrent pregnancy loss

, 2020; 13(4): 306-317.

Elham Abdollahi, Seyed Abdolrahim Rezaee, Nafiseh Saghafi, Maryam Rastin, Vicki Clifton, Amirhossein Sahebkar and Houshang Rafatpanah*


DOI: 10.2174/1874467213666200303130153


Research Article

Mechanism involved in fortification by berberine in cddp-induced nephrotoxicity

, 2020; 13(4): 342-352.

Vipin K. Verma, Salma Malik, Ekta Mutneja, Anil K. Sahu, Kumari Rupashi, Amit K. Dinda, Dharamvir S. Arya and Jagriti Bhatia*


DOI: 10.2174/1874467213666200220142202



Review Article

Fat10: Function and relationship with cancer

, 2020; 13(3): 182-191.

Senfeng Xiang, Xuejing Shao, Ji Cao, Bo Yang, Qiaojun He* and Meidan Ying*


DOI: 10.2174/1874467212666191113130312



Review Article

Radio-susceptibility of nasopharyngeal carcinoma: Focus on epstein-barr virus, micrornas, long non-coding rnas and circular rnas

, 2020; 13(3): 192-205.

Fanghong Lei, Tongda Lei, Yun Huang, Mingxiu Yang, Mingchu Liao* and Weiguo Huang*


DOI: 10.2174/1874467213666191227104646



Most Accessed Articles



FAT10: Function and Relationship with Cancer

, 2020; 13(3): 182-191.

Senfeng Xiang, Xuejing Shao, Ji Cao, Bo Yang, Qiaojun He* and Meidan Ying*


DOI: 10.2174/1874467212666191113130312



Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway

, 2021; 14(1): 101-111.

Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao* and Shilin Yang


DOI: 10.2174/1874467213666200611141337




Valproic acid, A Potential Inducer of Osteogenesis in Mouse Mesenchymal Stem Cells

, 2021; 14(1): 27-35.

Narayanan Akshaya, Prakash Prasith, Balakrishnan Abinaya, Badrinath Ashwin, S.V. Chandran and Nagarajan Selvamurugan*


DOI: 10.2174/1874467213666200713102410



Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats

, 2021; 14(2): 245-252.

Nobuo Izumo*, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*


DOI: 10.2174/1570163817666200430002937


miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway

, 2020; 13(4): 328-341.

Baiyang Ding, Shujuan Xu, Xiumin Sun, Jianming Gao, Wenlei Nie and Hongguang Xu *


DOI: 10.2174/1874467213666200204143740



Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1

, 2021; 14(2): 138-149.

Mohammed Abul Kashem, Omar Šerý, David V. Pow, Benjamin D. Rowlands, Caroline D. Rae and Vladimir J. Balcar*


DOI: 10.2174/1874467213666200424155244



Interleukin-19 as an Immunoregulatory Cytokine

, 2021; 14(2): 191-199.

Yasuyuki Fujimoto, Nobuyuki Kuramoto, Masanori Yoneyama and Yasu-Taka Azuma*


DOI: 10.2174/1874467213666200424151528



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