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Current Molecular Pharmacology

Volume 14, 6 Issues, 2021
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 14

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Number 3









Review Article

Recent Advances in Herbal Nanomedicines for Cancer Treatment

, 14(3): 292 - 305

Deepak Pradhan, Prativa Biswasroy, Amita Sahu, Dipak K. Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1874467213666200525010624




Review Article

Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression

, 14(3): 321 - 332

Saurabh Satija*, Harpreet Kaur, Murtaza M. Tambuwala, Prabal Sharma, Manish Vyas, Navneet Khurana, Neha Sharma, Hamid A. Bakshi, Nitin B. Charbe, Flavia C. Zacconi, Alaa A. Aljabali, Srinivas Nammi, Harish Dureja, Thakur G. Singh, Gaurav Gupta, Daljeet S. Dhanjal, Kamal Dua, Dinesh K. Chellappan* and Meenu Mehta*


DOI: 10.2174/1874467214666210120154929






Current Molecular Pharmacology, Volume 14 (2021) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Thioacetamide-Induced Norepinephrine Production by Hepatocytes is Associated with Hepatic Stellate Cell Activation and Liver Fibrosis


Wei-Chien Tang, Ya-Wen Chang, Mingtian Che, Mei-Hui Wang, Keith K. Lai, Patrick T. Fueger, Wendong Huang, Shwu-Bin Lin* and Keane K. Y. Lai*


DOI: 10.2174/1874467214666210412144416
View Abstract View on PubMed





Pretreatment with Gallic Acid Mitigates Cyclophosphamide Induced Inflammation and Oxidative Stress in Mice


Saeed Baharmi, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri and Hadi Kalantar*


DOI: 10.2174/1874467214666210531162741
View Abstract View on PubMed



Novel Strategy in Breast Cancer Therapy: Revealing The Bright Side of Ginsenosides


Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Hossein Saleki, Mahdi Vasheghani Farahani, Seyed Omid Sharifzadeh, Zahra Ghahremaniyeh, Atefe Kazemzade Bejandi, Kiavash Hushmandi, Milad Ashrafizadeh* and Haroon Khan*


DOI: 10.2174/1874467214666210120153348
View Abstract View on PubMed





Abstracts Ahead of Print

Nanoencapsulation of Polyphenols as Drugs and Supplements for Enhancing Therapeutic Profile - A Review


Saima Khatoon, Nida Kalam, Mohd. Farooq Shaikh*, M Saquib Hasnain, Aurangzeb Khurram Hafiz and Mohammed Tahir Ansari*


DOI: 10.2174/1874467214666210922120924
View Abstract



Key miRNAs in Modulating Aging and Longevity: A Focus on Signaling Pathways and Cellular Targets


Aliabbas Zia, Tahereh Farkhondeh, Faezeh Sahebdel, Ali Mohammad Pourbagher-Shahri and Saeed Samarghandian*


DOI: 10.2174/1874467214666210917141541
View Abstract


Novel Chalcone BDD-39 Mitigated Diabetic Nephropathy through the Activation of Nrf2/ARE Signaling


Temitope Adelusi, Xizhi Li, Liu Xu, Lei Du, Meng Hao, Xueyan Zhou, Apu Chowdhry, Ying Sun, Xiaoke Gu, Qian Lu and Xiaoxing Yin*


DOI: 10.2174/1874467214666210915145104
View Abstract


The role of miR-129-5p in cancer: a novel therapeutic target


Shan Xu, Wei Li, Jing Wu, Yuru Lu, Ming Xie, Yanlan Li, Juan Zou, Tiebing Zeng and Hui Ling*


DOI: 10.2174/1874467214666210914122010
View Abstract


Sports Related Brain Injury and Neurodegeneration in Athletes


Vipin V. Dhote*, Muthu Kumaradoss Mohan Maruga Raja, Prem Samundre, Supriya Sharma, Shraddha Anwikar and Aman B. Upaganlawar


DOI: 10.2174/1874467214666210910114324
View Abstract


Nitric Oxide Modulation as a Potential Molecular Mechanism Underlying the Protective Role of NaHS in Liver Ischemia Reperfusion Injury


Salwa A. Ibrahim*, Seham A. Abdel-Gaber, Mohamed A. Ibrahim, Entesar F. Amin, Rehab K. Mohammed and Aly M. Abdelrahman


DOI: 10.2174/1874467214666210909154609
View Abstract


Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics


Chandrabose Selvaraj*, Dhurvas Chandrasekaran Dinesh, Petra Krafcikova, Evzen Boura, Murali Aarthy, Muthuraja Arun Pravin and Sanjeev Kumar Singh*


DOI: 10.2174/1874467214666210906125959
View Abstract




Published Contents

Editor's Choice

Recent Advances in Herbal Nanomedicines for Cancer Treatment

, 2021; 14(3): 292 - 305

Deepak Pradhan, Prativa Biswasroy, Amita Sahu, Dipak K. Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1874467213666200525010624



Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression

, 2021; 14(3): 321 - 332

Saurabh Satija*, Harpreet Kaur, Murtaza M. Tambuwala, Prabal Sharma, Manish Vyas, Navneet Khurana, Neha Sharma, Hamid A. Bakshi, Nitin B. Charbe, Flavia C. Zacconi, Alaa A. Aljabali, Srinivas Nammi, Harish Dureja, Thakur G. Singh, Gaurav Gupta, Daljeet S. Dhanjal, Kamal Dua, Dinesh K. Chellappan* and Meenu Mehta*


DOI: 10.2174/1874467214666210120154929




TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy

, 2021; 14(2): 123 - 131

Kazuhiro Nishiyama, Tomohiro Tanaka, Akiyuki Nishimura and Motohiro Nishida*


DOI: 10.2174/1874467213666200407090121



Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis

, 2021; 14(2): 165 - 169

Yoshifumi Takahata*, Tomohiko Murakami, Kenji Hata and Riko Nishimura


DOI: 10.2174/1874467213666200417122933




Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma

, 2020; 13(4): 261 - 272

Mengna Wu, Huajie Miao, Rong Fu, Jie Zhang* and Wenjie Zheng *


DOI: 10.2174/1874467213666200224102820




Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

, 2020; 13(3): 216 - 223

Tatiana V. Vyunova*, Lioudmila A. Andreeva, Konstantin V. Shevchenko, Vladimir V. Grigoriev, Vladimir A. Palyulin, Mstislav I. Lavrov, Ekaterina V. Bondarenko, Elena E. Kalashnikova and Nikolay F. Myasoedov


DOI: 10.2174/1874467213666200303140834



Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis

, 2020; 13(2): 150 - 172

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935



Open Access Articles

Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats

, 2021; 14(2): 245 - 252

Nobuo Izumo*, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*





Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway

, 2021; 14(1): 101 - 111

Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao* and Shilin Yang




Ticagrelor Ameliorates Bleomycin-induced Pulmonary Fibrosis in Rats by the Inhibition of TGF-β1/Smad3 and PI3K/AKT/mTOR Pathways

, 2021; 14: 1 - 12 (E-Pub Ahead of Print)

Hanaa Wanas*, Zeinab El Shereef, Laila Rashed and Basma Emad Aboulhoda




Dual Targeting of Autophagy and NF-κB Pathway by PPARγ Contributes to the Inhibitory Effect of Demethoxycurcumin on NLRP3 Inflammasome Priming

, 2021; 14: 1 - 8 (E-Pub Ahead of Print)

Jing Tang, Xiaoxue Tan, Xiangmi Huang, Jie Zhang, Liang Chen, Aiyuan Li* and Deming Wang*




Anticancer Effects of Tacrolimus on Induced Hepatocellular Carcinoma in Mice

, 2021; 14: 1 - 12 (E-Pub Ahead of Print)

Shireen Sami Mahmoud, Samia Hussein*, Hayam Rashed, Eman M. A. Abdelghany and Alaa I. Ali





New Insights in Cannabinoid Receptor Structure and Signaling

, 2019; 12(3): 239 - 248

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*





Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*




Mitochondria-Targeted Drugs

, 2019; 12(3): 202 - 214

Roman A. Zinovkin* and Andrey A. Zamyatnin*




A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia

, 2019; 12(3): 195 - 201

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar




Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions

, 2019; 12(3): 184 - 194

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva




Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis

, 2019; 12(1): 27 - 49

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*




Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Most Cited Articles

Review Article

Mitochondria-targeted drugs

, 2019; 12(3): 202-214.

Roman A. Zinovkin* and Andrey A. Zamyatnin*


DOI: 10.2174/1874467212666181127151059


Review Article

New insights in cannabinoid receptor structure and signaling

, 2019; 12(3): 239-248.

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*


DOI: 10.2174/1874467212666190215112036


Review Article

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

, 2019; 12(1): 50-60.

Keywan Mortezaee, Nasser Hashemi Goradel, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1874467211666181010154709



Review Article

Pharmacokinetic and pharmacodynamic aspects of peyote and mescaline: Clinical and forensic repercussions

, 2019; 12(3): 184-194.

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva


DOI: 10.2174/1874467211666181010154139



Review Article

Mechanisms for radioprotection by melatonin; can it be used as a radiation countermeasure?

, 2019; 12(1): 2-11.

Peyman Amini, Hanifeh Mirtavoos-Mahyari, Elahe Motevaseli, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Mohsen Cheki, Bagher Farhood, Rasoul Yahyapour, Alireza Shirazi, Nouraddin Abdi Goushbolagh and Masoud Najafi*


DOI: 10.2174/1874467211666180802164449


Review Article

Targeting chromatin remodeling for cancer therapy

, 2019; 12(3): 215-229.

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*


DOI: 10.2174/1874467212666190215112915


Research Article

In-vitro pre-treatment of cancer cells with TGF-β1: A novel approach of tail vein lung cancer metastasis mouse model for anti-metastatic studies

, 2019; 12(4): 249-260.

Ghulam Jilany Khan*, Li Sun, Muhammad Abbas, Muhammad Naveed, Talha Jamshaid, Mirza Muhammad Faran Ashraf Baig and Shengtao Yuan*


DOI: 10.2174/1874467212666190306165703


Research Article

Effects of myo-inositol alone and in combination with seleno-l-methionine on cadmium-induced testicular damage in mice

, 2019; 12(4): 311-323.

Salvatore Benvenga, Antonio Micali*, Giovanni Pallio, Roberto Vita, Consuelo Malta, Domenico Puzzolo, Natasha Irrera, Francesco Squadrito, Domenica Altavilla and Letteria Minutoli


DOI: 10.2174/1874467212666190620143303



Research Article

Synergistic effect of epigenetic inhibitors decitabine and suberoylanilide hydroxamic acid on colorectal cancer in vitro

, 2019; 12(4): 281-300.

Sonia Abou Najem, Ghada Khawaja, Mohammad Hassan Hodroj and Sandra Rizk*


DOI: 10.2174/1874467212666190313154531


Review Article

A contemporary overview of PPARα/γ dual agonists for the management of diabetic dyslipidemia

, 2019; 12(3): 195-201.

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar


DOI: 10.2174/1874467212666190111165015


Review Article

Kinase targets for mycolic acid biosynthesis in mycobacterium tuberculosis

, 2019; 12(1): 27-49.

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*


DOI: 10.2174/1874467211666181025141114


Research Article

Mir-4319 suppresses the growth of esophageal squamous cell carcinoma via targeting NLRC5

, 2020; 13(2): 144-149.

Xiao Hu, Min Wang, Lei Cao, Li Cong, Yujie Gao, Jianwei Lu, Jifeng Feng, Bo Shen and Delin Liu*


DOI: 10.2174/1874467212666191119094636



Most Accessed Articles

Recent Advances in Herbal Nanomedicines for Cancer Treatment

, 2021; 14(3): 292-305.

Deepak Pradhan, Prativa Biswasroy, Amita Sahu, Dipak K. Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1874467213666200525010624


Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression

, 2021; 14(3): 321-332.

Saurabh Satija*, Harpreet Kaur, Murtaza M. Tambuwala, Prabal Sharma, Manish Vyas, Navneet Khurana, Neha Sharma, Hamid A. Bakshi, Nitin B. Charbe, Flavia C. Zacconi, Alaa A. Aljabali, Srinivas Nammi, Harish Dureja, Thakur G. Singh, Gaurav Gupta, Daljeet S. Dhanjal, Kamal Dua, Dinesh K. Chellappan* and Meenu Mehta*


DOI: 10.2174/1874467214666210120154929






Differential Modulation of Autophagy Contributes to the Protective Effects of Resveratrol and Co-Enzyme Q10 in Photoaged Mice

, 2021; 14(3): 458-468.

Dalia K. Mostafa*, Shaimaa I. Omar, Amany A. Abdellatif, Osama A. Sorour, Omnia A. Nayel and Marwa R. Abod Al Obaidi


DOI: 10.2174/1874467213666200730114547












Editor-in-Chief

graphic
Michael Kahn
(16435 citations)
Beckman Research Institute
City of Hope
Duarte, CA 91010-3000
(USA)
View Full Editorial Board

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Journal History

Current Molecular Pharmacology Journal was launched in 2008. Prof. Michael Kahn serves as the Editor-in-Chief of the journal.

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