Quantitative Structure-Activity Relationship (QSAR) is a field where true multidisciplinary approaches are being used. This volume titled Recent Trends on QSAR in the Pharmaceutical Perceptions offers an overview on the latest advancements in the field. The e-book explains both basic approaches and new approaches and ideas in QSAR research, providing readers with an impression of recent inclinations and advances in different aspects of the QSAR strategies, such as descriptors, methods of modeling and validation. This e-book is a valuable reference for pharmacologists, medicinal chemists, drug designers, biotechnologists and industry (pharmaceutical and chemical) professionals. It should serve as an important reference material to stimulate interactions and bridge the gap between participants in academia and industries.

Reviews in Pharmaceutical and Biomedical Analysis contains coverage and review of new trends and applications in all areas of pharmaceutical, biomedical and analytical chemistry. Authors have contributed review articles according to their expertise on various relevant topics. The book's aim is to cover important instrumental analytical methods that are applied to the analysis of compounds with pharmaceutical and biomedical interest, including liquid and gas chromatography, electrophoresis & related techniques, mass spectrometry, hyphenated techniques, automated analytical techniques, spectrometry, luminescence, electroanalysis etc. Since the analysis of pharmaceuticals in a variety of matrices (formulations, biological material, environmental samples) is and will continue to be a "hot" topic, such a review book will be of interest to a very broad spectrum of scientists involved in chemistry and medicine.

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices & Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are a common part of regional diets and folk medicine.

<p></p> Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are common part of regional diets and folk medicine. <p></p> The second volume of this series features 6 reviews of unique herbs and seeds: <p></p> 1. Tamarind (Tamarindus indica L.): A Review of its Use as a Spice, a Culinary Herb and Medicinal Applications <p></p> 2. Piper nigrum (Black pepper): A Flavor for Health <p></p> 3. Coriander Seeds – Ethno-medicinal, Phytochemical and Pharmacological Profile <p></p> 4. The Fenugreek Seed: Therapeutic Properties and Applications <p></p> 5. Biological Activities of Foeniculum vulgare Mill <p></p> 6. Exploration of Dill Seeds (Anethum graveolens): An Ayurpharmacomic Approach <p></p>

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are common part of regional diets and folk medicine. The third volume of this series features the following reviews: 1. Anthelmintic Properties of Cinnamon for the Control of Agricultural and Public Health Pests 2. Nutraceutical Attributes of Tamarindus indica L. - Devils’ Tree with Sour Date 3. An Overview of the Tamarind (Tamarindus indica L.) Fruit: A Potential source of Nutritional and Health promoting Phytoconstituents 4. The Clinical Overview of Turmeric, Turmeric-based Medicines, and Turmeric Isolates 5. Origanum majorana: The Fragrance of Health 6. Black Pepper (Piper nigrum L.): The King of Spices 7. Coriander: A Herb with Multiple Benefits 8. Flax Seed (Linum usitatissimum) a Potential Functional Food Source

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are a common part of regional diets and folk medicine.

The fourth volume of this series features the following reviews:

1. Pharmacological effects of Curcuma longa, focused on anti-inflammatory, antioxidant and immunomodulatory effects

2. Ethnomedicinal uses, Phytochemistry, Pharmacological effects, Pre-clinical and Clinical studies on flaxseed: A spice and culinary herb-based formulations and its constituents

3. Nigella sativa (Prophetic medicine): The Miracle Herb

4. Properties of Mexican oregano (Lippia spp.) essential oils and their use in aquaculture

5. Curry leaf: An insight into its Pharmacological activities, Medicinal profile, and Phytochemistry

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are a common part of regional diets and folk medicine. <p> The fifth volume of this series features research on a variety of spices some of which appear in the series for the first time. <p> 1. Clove: The Spice of Polyvalent Merit <p> 2. Black Cumin Seeds: From Ancient Medicine to Current Clinical Trials <p> 3. The Evolution of Mentha arvensis (L.) As Potential Multifunctional Herbal Medicine: Traditional And Experimental Evidence <p> 4. Zingiber officinale: The Golden Spice as Portrayed in Ayurveda <p> 5. Effects of Cinnamon on Health and its Potential as a Functional Food Ingredient <p> 6. Sumac: A Spice with Many Health Benefits

Understanding the dispersion and the deposition of inertial particles convected by turbulent flows is a domain of research of considerable industrial interest. Inertial particle transport and dispersion are encountered in a wide range of flow configurations, whether they are of industrial or environmental character. Conventional models for turbulent dispersed flows do not appear capable of meeting the growing needs of chemical, mechanical and petroleum industries in this regard and physical environment testing is prohibitive. Direct Numerical Simulation (DNS) and Large Eddy Simulation (LES) have become powerful tools for the investigation of particle-laden turbulent flows with the help of advances in computing resources. The hybrid Eulerian-Lagrangian approach plays a key role in predicting inertial particle dispersion and deposition. This ebook explains the use of stochastic tools to enhance the accuracy of the Eulerian-Lagrangian large eddy simulation of particle-laden turbulent flows of practical interest. The book should be a useful resource for chemical, mechanical, petroleum and environmental engineering postgraduates and researchers interested in applying tractable yet powerful numerical tools to solve problems involving multiphase flows.

Drug discovery is still a process which involves screening of a large number of chemical compounds against a defined biological target. However, this approach is now being gradually replaced by more rational and knowledge-based approaches, such as in sillico screening and target based drug development. Increase in the cost of development of NME (New Molecular Entities) and productivity crises in pharmaceutical industry are catalyzing this change. Spectacular advances in the field of use of NMR spectroscopy in drug discovery and development have been triggered by a greater understanding of the disease process at the molecular level. While NMR is generally valued as an important tool for structure determination and more recently as a non-invasive diagnostic technique, its potential in drug discovery is based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parameters which are highly sensitive to the exact molecular environments , and therefore yield information about how a small molecule (candidate compound) binds to a target protein (receptor) or to other macromolecules. These NMR parameters are also used to exactly map the part of the macromolecular target to which the ligand is bound. As a result, NMR is now extensively used as an efficient tool in the drug (ligand) discovery and optimization process or for the assessment of target drug ability. Recent advances in NMR hardware and methodology have provided a fresh impetus in the area of pharmaceutical innovation and productivity. This book is aimed to present recent cutting edge knowledge, practices and experiences in this important field. The book comprises seven scholarly written articles . Mailavaram and Devarakonda in their introductory review skillfully summarize the broad approaches of NMR-based drug discovery . Park and Kim focus on the use of NMR spectroscopic techniques in the study of drug delivery, drug release and other pharmaceutic parameters. Roberto and Marina provide a chronological account of fragment-based drug discovery by using NMR-based screening methods. Specific utilization of NMR-based techniques in the discovery and development of anticancer drugs is reviewed by Solomon and Lee. Ramalho et al. review another fascinating application of NMR in understanding the behavior and radio sensitizing properties of bioreductive drugs. Zoppetti comprehensively reviews the application of NMR spectroscopy in the study of host-guest cyclodextrin complexes, particularly their use as drug delivery vehicles. A concise review is contributed by Nhat and Hong on recent advances in the field of application of NMR in structure-activity relationship study of nanostructure drugs. These contributions of outstanding group of experts make this a very useful treatise of highly readable articles. Our felicitations and gratitude goes to them. The book will hopefully fulfill an important need of the scientific community by providing comprehensive reviews on cutting edge topics written by leading experts in the field. We extend our warmest thanks to the staff of Bentham Science Publishers, particularly, to Mr. Mahmood Alam (Director), Ms. Taqdees Malik (Editorial Assistant) and Ms. Sadaf Idrees Khan (Composer) for undertaking the important task of closely coordinating with the contributors and preparing the content lists, index, etc.

Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques. This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing. Key Features: - Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS) - Provides a complete framework on SERS based biosensing with concise chapters - Focuses on different active molecules critical to SERS and associated developed nanoassemblies - Presents information about ongoing research on SERS imaging applications - Highlights bottlenecks of SERS technique in biosensing - Includes references for further reading This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.