Immunology of Pregnancy 2013

Part B: Immunoregulation at the Interface by Placental Suppressor Factors

Author(s): Gérard Chaouat

Pp: 525-535 (11)

DOI: 10.2174/9781608057337113010025

* (Excluding Mailing and Handling)


In this brief sub-chapter we review first quickly pregnancy specific proteins (which were at the time seen in a context of general dampening of maternal immune response) to discuss then anergy inducing placental factors and exosomes. We finish by dealing with placenta integrated retroviruses, and their immunosuppressive properties.

Keywords: Placenta, Immunity, Suppression, Induction, IDO, HcG, PIF, EPF.PIBF, HLA-G, Factors, Anergy, Exosomes, IL-10, Retrovirus, Syncitin.

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