Immunology of Pregnancy 2013

Part C: A Summary of Cytokine Networks and Embryo: A Short Overview

Author(s): Gérard Chaouat

Pp: 238-279 (42)

DOI: 10.2174/9781608057337113010014

* (Excluding Mailing and Handling)


In this relatively short review, after recaling the immunotrophism theory and the Th1 /Th2 paradigm, and the fact that a major discovery in the field was that “immunologic” molecules are produced by cells of the reproductive tract of non-immune lineage, we try to summarize the main cytokines involvement in pregnancy, though redundancy and chaos like functions makes it sometimes impossible to ascribe a defined role to a single cytokine or even cytokine family.

Keywords: Cytokine, Interleukin, Angiogenesis, Complement, Th1, Th2, Tregs, NK, Network, Uterus, Placenta, Implantation, Pregnancy, Failure, Abortion.

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