Tinospora cordifolia is a Rasayana herb of Ayurveda, commonly known as
“Heavenly Elixir” or “Amrita”, and one of the most exploited herbs in herbal
medicines. T. cordifolia is well reported for its various pharmacological properties,
such as anti-diabetic, anti-inflammatory, antipyretic, immunomodulatory, anti-cancer,
cardioprotective, neuroprotective, and hepatoprotective activities. The prevalence of
neurodegenerative diseases and other neurologic disorders is increasing worldwide.
Oxidative stress and neuroinflammation are among the major pathologic mechanisms
underlying neurodegenerative diseases. This chapter discusses the pieces of scientific
evidence of the beneficial effects of T. cordifolia in various brain-related ailments.
Various research groups have demonstrated the ability of T. cordifolia and its extracts
to normalize oxidative stress and suppress the inflammatory response against various
causative agents, and thus suggested that T. cordifolia has the potential to be a
neurotherapeutic drug candidate in the future.
Keywords: Herbal medicine, Neuroinflammation, Neurodegeneration, Neurologic disorders, Oxidative stress, T. cordifolia.