Among different causes of chronic low back pain, Modic changes of the
endplates have been identified as an MRI-image representation of end stage
degenerative disc disease. Painful innervation of these degenerative endplates from
within the vertebral body by arborization of the basivertebral nerve towards these
endplates has been demonstrated. Ablation of the basivertebral nerve has been
identified as one possible way to treat chronic low back pain. This chapter describes the
transforaminal epiduroscopic laser ablation of the basivertebral nerve and its associated
Keywords: Basivertebral nerve, Chronic low back pain, Epiduroscopy, Laser ablation, Modic changes, Transforaminal approach.