The name of Vitamin B6 refers to a group of vitamers based on a core
pyridine structure from which a synthetic homolog, pyridoxine hydrochloride, has been
obtained, for pharmaceutical purposes. However, that synthetic compound is
responsible for different allergic reactions, mainly delayed, cell-mediated-type.
Because of the vitamin B6 photosensitivity, various cases of adverse cutaneous
reactions, above all photoallergic, are described in the literature following the use of
systemic assumption of vitamin B6 or its skin application from vitamin enriched
topical products like creams and cosmetics.
Keywords: Allergic Contact Dermatitis, Anaphylaxis, Delayed-type Reaction,
Immediate-type Reaction, Photo Allergy, Photosensitivity, Pyridoxine, Pyridoxine
Hydrochloride, Vitamin B6.
