Hypersensitivity to Vitamins

Vitamin B6 (Pyridoxine)

Author(s): Gianfranco Calogiuri

Pp: 44-51 (8)

DOI: 10.2174/9781681088921121010008

* (Excluding Mailing and Handling)


The name of Vitamin B6 refers to a group of vitamers based on a core pyridine structure from which a synthetic homolog, pyridoxine hydrochloride, has been obtained, for pharmaceutical purposes. However, that synthetic compound is responsible for different allergic reactions, mainly delayed, cell-mediated-type. Because of the vitamin B6 photosensitivity, various cases of adverse cutaneous reactions, above all photoallergic, are described in the literature following the use of systemic assumption of vitamin B6 or its skin application from vitamin enriched topical products like creams and cosmetics.

Keywords: Allergic Contact Dermatitis, Anaphylaxis, Delayed-type Reaction, Immediate-type Reaction, Photo Allergy, Photosensitivity, Pyridoxine, Pyridoxine Hydrochloride, Vitamin B6.

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