Pediatric Chronic Rhinosinusitis (PCRS) is a common condition in otolaryngological practice. PCRS remains ill-defined as a condition as it remains difficult to establish as a diagnosis. PCRS may co-exist with other widespread conditions such as allergic rhinosinusitis and adenoiditis. Recent efforts have been targeted at defining this condition and to develop stepwise treatment. A consensus of statement was recently put out defining PCRS as at least 90 continuous days of nasal symptoms with corresponding endoscopic and/or image findings in a patient who is 18 years old or younger. With a working definition, research has focused on developing stepwise treatments ranging from medical management to endoscopic sinus surgery. This chapter focuses on discussing the developed treatments for PCRS.