Nanotechnology has shown immense promise for advancing blood glucose control. This technology offers the potential to safeguard pancreatic cells from autoimmune destruction by driving the creation of innovative therapeutic agents that can be delivered to specific targets. In this book, you will find a comprehensive exploration of diabetes and its approved medical treatments. The book delves into how nanotechnology can amplify the efficacy of current treatment modalities, potentially paving the way for a gene therapy solution to combat this disease. Starting with the history of diabetes treatment, the book explains treatment challenges for diabetes before getting into the three ways nanoscience is helping in diabetes treatment: insulin delivery, drug delivery and nucleotide delivery. Each chapter is contributed by accomplished experts in their respective fields, who strive to offer a thorough, yet accessible discussion of the subject.

Computational Toxicology for Drug Safety and a Sustainable Environment is a primer on computational techniques in environmental toxicology for scholars. The book presents 9 in-depth chapters authored by expert academicians and scientists aimed to give readers an understanding of how computational models, software and algorithms are being used to predict toxicological profiles of chemical compounds. The book also aims to help academics view toxicological assessment from the lens of sustainability by providing an overview of the recent developments in environmentally-friendly practices. The chapters review the strengths and weaknesses of the existing methodologies, and cover new developments in computational tools to explain how researchers aim to get accurate results. Each chapter features a simple introduction and list of references to benefit a broad range of academic readers. List of topics: 1. Applications of computational toxicology in pharmaceuticals, environmental and industrial practices 2. Verification, validation and sensitivity studies of computational models used in toxicology assessment 3. Computational toxicological approaches for drug profiling and development of online clinical repositories 4. How to neutralize chemicals that kill environment and humans: an application of computational toxicology 5. Adverse environmental impact of pharmaceutical waste and its computational assessment 6. Computational aspects of organochlorine compounds: DFT study and molecular docking calculations 7. In-silico studies of anisole and glyoxylic acid derivatives 8. Computational toxicology studies of chemical compounds released from firecrackers 9. Computational nanotoxicology and its applications.

Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career researchers. The book aims to help readers understand how to discover molecules with therapeutic potential by bringing essential information about the subject into one volume. Key Features . Presents the concepts and evolution of classical techniques, up to the use of modern methods based on computational chemistry in accessible format. . Gives a primer on structure- and ligand-based drug design and their predictive capacity to discover new drugs. . Explains theoretical fundamentals and applications of computer-aided drug design. . Focuses on a range of applications of the computations tools, such as molecular docking; molecular dynamics simulations; homology modeling, pharmacophore modeling, quantitative structure-activity relationships (QSAR), density functional theory (DFT), fragment-based drug design (FBDD), and free energy perturbation (FEP). . Includes scientific reference for advanced readers

Learn the skills of medical history taking and physical examination with this accessible and comprehensive textbook. Designed for medical students and clinicians, it simplifies complex concepts and procedures to empower you with essential skills for effective patient consultation. Key Features -Clear and Simple Language: This book uses plain and straightforward language, making the intricate world of medical history taking and physical examination easy to understand, even for beginners. -Real Illustrations: Learn from real pictures that vividly depict clinical scenarios, helping you bridge the gap between theory and practice. -Step-by-Step Guidelines: Follow systematic guidelines for history taking and physical examination. From patient introduction and consent to comprehensive body system examinations, each step is clearly outlined, ensuring you never miss a crucial detail. -Specialized Examination Section: Includes a specialized examination section, covering various body systems like cardiovascular, respiratory, abdominal, and the central nervous system. Understand the physical basis of clinical signs to enhance your diagnostic skills. Quick Guide in History Taking and Physical Examination helps you to master the art of clinical examination, develop the confidence to take accurate medical histories, and interpret symptoms and signs effectively. It serves as an essential companion for medical students and residents on their journey to become a proficient clinician.

In the battle against the COVID-19 pandemic, the integration of Internet of Things (IoT) technologies has played a pivotal role in reshaping public health and healthcare delivery. Interconnected devices have demonstrated their capacity to collect, transmit, and analyze data, significantly impacting various aspects of pandemic management. COVID-19 Monitoring with IoT Devices is a comprehensive guide to measuring the impact of COVID-19 infection and monitoring outbreak metrics. Beginning with an introduction to SARS-CoV-2 and its symptoms, the book presents chapters on machine learning (supervised and unsupervised algorithms) and techniques to predict COVID-19 outcomes. The book concludes with the role of IoT technology in detecting COVID-19 infections within a community, showcasing different computing models applicable to specific use-cases. Key Features: Explores the pivotal role of IoT technology in the fight against the COVID-19 pandemic. Covers a data-driven approach to COVID-19 monitoring by explaining methods for data collection, prediction, and analysis. Includes specific recommendations for machine learning algorithms designed for COVID-19 monitoring. Easy-to-read structured chapters suitable for novices in computer science and biomedical engineering. COVID-19 Monitoring with IoT Devices provides a valuable resource for understanding the role of IoT technology in managing and mitigating the impact of COVID-19, and developing adequate infection control policies. It also showcases the potential of IoT for future research and applications in the healthcare sector. This book is intended for a diverse readership, including academicians, industry professionals, researchers, and healthcare practitioners.

This comprehensive compendium unravels the intricacies of three common and daunting skeletal disorders: osteoporosis, osteoarthritis, and rheumatoid arthritis. These ailments afflict people across all age groups, demanding a deeper understanding of their diagnostic, prognostic, preventive, and therapeutic dimensions. It presents seven key topics written by medical experts that explore research on these diseases: Chronic Lung Disease and Osteoporosis An exploration of the intricate link between chronic lung ailments and osteoporosis. AI Detection of Knee Osteoarthritis Recent use of artificial intelligence aiding knee osteoarthritis identification. Inflammatory Signalling in Rheumatoid Arthritis Covers the role of cytokines and chemokines in the context of rheumatoid arthritis. Vitamin D, Immune System, and Bone Health Unveils the vital implications of Vitamin D on the immune system and bone health. Bone Water and Hydration Effects A review of the impact of drugs on bone hydration status through the lens of bone water. Dietary Patterns and Rheumatoid Arthritis An analysis of the connection between dietary habits and rheumatoid arthritis. Quality of Life in Rheumatoid Arthritis Patients (Chapters 112-130): An examination of the self-perceived quality of life in Rheumatoid Arthritis patients, comparing South Asian and British White populations. This knowledge-rich treatise is a valuable resource for patients and their families battling these skeletal ailments. It's equally beneficial for medical students, orthopedists, researchers, and anyone eager to grasp the complexities of these widespread skeletal pathologies.

Natural Products for Treatment of Skin and Soft Tissue Disorders presents a simple and straightforward exploration of the role medicinal plants play in treating a diverse range of skin-related disorders. With contributions from researchers worldwide, this book delves into the pathology of skin conditions such as eczema, superficial mycoses, acne, vitiligo, and skin ulcers, providing effective treatment protocols using natural remedies. It also addresses prevalent disorders like atopic dermatitis and skin infections in developing countries. Finally, the book sheds light on the rising concern of skin cancer and potential natural therapeutic approaches. Readers will be equipped with the knowledge to harness the power of natural medicines in their dermatology practice. This comprehensive resource serves as a handbook for medical residents, students and dermatologists, offering invaluable insights into the potential of medicinal plants for the treatment of skin and soft tissue disorders.

Natural Products for Skin Diseases: A Treasure Trove for Dermatologic Therapy is an enlightening journey through the realm of natural remedies for various skin diseases. The editors have compiled information on effective and holistic treatment approaches that can be applied in clinical settings. This book brings diverse range of topics, including skin protection against harmful radiation, natural remedies for burns and wounds, management of skin pigmentation issues, and herbal treatments for scabies. It also explores the potential of natural cosmetics and their future applications, along with the use of natural products and nanoparticles in skin delivery. All chapters are contributed by experts in dermatology and herbal medicine, and are supplemented with scientific references for advanced readers. The book primarily serves as a textbook for students in medicine and dermatologists in training. It also serves as a valuable guide for dermatologists, researchers, and healthcare professionals, revealing the treasure trove of benefits that natural products offer for treating skin diseases.

Common Pediatric Diseases: Current Challenges provides an update on different diseases and problems that affect child and adolescent health. The book starts with a quick introduction to challenges in the field of pediatrics and child health. This is followed by chapters on the outcomes of sexting, the integrated care of children with neurodevelopmental disorders, the influence of non-genetic transgenerational inheritance on children and adolescents’ development and the approach to pediatric genetic epilepsy. Additional topics covered in the book include the medical and social outcomes of cardiac diseases along with a review on specific aspects of fetal and neonatal medicine (meconium-stained newborns, transient tachypnea of newborns and fetal tumors). The book also features a chapter on Autism Spectrum Disorder during infancy and its early symptoms. The concluding chapter covers medical futility controversies and end-of-life care.