Brain Tumour Drug Development provides a clear, multidisciplinary update on modern therapies for glioblastoma and other aggressive brain tumours. The book focuses on improving drug precision, crossing the blood-brain barrier, identifying biomarkers, designing effective trials, and accelerating translation from research to real patient care. Key Features Overcomes the blood-brain barrier using advanced delivery methods Improves drug penetration & specificity with nano and polymer-based systems Explores new therapies through immunotherapy, gene therapy, and personalised medicine Builds preclinical models & identifies biomarkers to support clinical success Designs regulatory-aligned clinical trial strategies for faster translation

Handbook of Practical Pharmacology – I serves as a vital bridge between theoretical pharmacology and laboratory application, equipping learners with the experimental skills essential to understanding drug actions through hands-on animal studies. A comprehensive, curriculum-based guide designed for second-year B. Pharm. students, fully aligned with the Pharmacy Council of India’s 2014 regulations. The book introduces students to fundamental laboratory concepts, animal handling as per CCSEA guidelines, drug administration routes, and experimental models like Rotarod, Actophotometer, and rabbit eye studies. It explores pharmacodynamic responses to various classes of drugs, including hepatic enzyme inducers, skeletal muscle relaxants, anticonvulsants, and anxiolytics. Each chapter combines clarity, precision, and ethical awareness, ensuring reproducibility and adherence to professional standards. Serving both as a laboratory manual and a learning companion, this handbook enhances analytical thinking and experimental competence, helping students gain a deeper, practice-based understanding of pharmacology. Key Features · Aligns with the PCI 2014 syllabus for second-year B. Pharm. students. · Explains fundamental experimental pharmacology concepts and instrumentation. · Demonstrates animal handling and drug administration techniques per CCSEA guidelines. · Guides pharmacodynamic testing using established models like Rotarod, Actophotometer, and MES. · Promotes laboratory competence, ethical compliance, and analytical reasoning in pharmacology

Drug Repurposing for Antivirals is a timely volume bridging pharmacology, virology, and computational science to present a cohesive understanding of the scientific and translational potential of drug repurposing in antiviral therapy with innovative strategies of finding new antiviral applications for existing drugs, an approach that shortens development timelines, reduces costs, and accelerates clinical deployment The book covers core concepts, from historical successes to modern applications in combating viral diseases. It explores computational screening, molecular docking, and AI-driven tools for identifying candidate molecules; experimental validation methods; and real-world case studies involving influenza, SARS-CoV-2, HIV, and hepatitis viruses. Special focus is given to host-targeted antivirals, broad-spectrum agents, and strategies to counter viral resistance. Regulatory aspects, challenges, and future directions for integrating repurposed antivirals into clinical practice are also discussed. Key Features: Integrates theory, methodology, and real-world case studies. Covers both computational and experimental approaches. Highlights implications for pandemic preparedness and rapid-response drug discovery. Includes contributions from leading experts in virology, medicinal chemistry, and pharmacology.

New Drugs Targeting Antibiotic-Resistant Bacteria: Recent Advances examines the molecular, pharmacological, and clinical dimensions of resistance development and highlights innovative therapeutic approaches aimed at overcoming multidrug-resistant organisms (MDROs), providing an in-depth exploration of emerging strategies to combat one of the most urgent public health challenges of our time—antimicrobial resistance (AMR). Beginning with the mechanisms underlying bacterial resistance such as β-lactamase production, efflux pump activity, and membrane protein modification, the text underscores the growing threat posed by ESKAPE pathogens and CDC-classified priority infections. Chapters also explore cutting-edge interventions including bacteriophage therapy, discovery of novel antibacterial compounds from natural sources, and the use of nanoparticles and quorum-sensing inhibitors to suppress bacterial virulence. Further sections discuss carbapenemase-mediated resistance, emphasizing enzyme classification, detection strategies, and the importance of clinical microbiology in guiding antibiotic stewardship. By integrating one-health perspectives that consider human, animal, and environmental dimensions, this book presents a holistic roadmap for addressing resistance evolution through innovation and responsible antibiotic use. Key Features Examines the molecular mechanisms driving antibiotic resistance in key bacterial species Explores bacteriophage therapy as a promising alternative to conventional antimicrobials Discovers natural-source compounds and novel drug leads for future antibiotic development Analyses carbapenemase-mediated resistance and clinical detection techniques Evaluates new therapeutic approaches including nanoparticle-based treatments and quorum-sensing inhibition Promotes the one-health approach to tackling multidrug-resistant organisms globally

Technical Advances in Pharmacy: An Overview examines the convergence of digital transformation, automation, and data intelligence in revolutionizing drug discovery, formulation, and healthcare delivery Across twelve in-depth chapters the book presents a forward-looking exploration of how emerging technologies are reshaping the landscape of pharmaceutical sciences. The book also covers cutting-edge developments such as artificial intelligence in drug discovery, pharmacogenomics and personalized medicine, blockchain in pharmaceutical supply chains, 3D printing of dosage forms, tele pharmacy, data analytics, and automation in pharmacy practice. By integrating computational modelling with experimental techniques, the text highlights the translational potential of modern technologies in enhancing drug development, patient adherence, and clinical outcomes. Serving as both a reference and a roadmap, this volume bridges traditional pharmaceutical foundations with next-generation innovations, offering readers an insightful perspective on the technological evolution shaping the future of pharmacy. Key Features Examines the role of artificial intelligence, pharmacogenomics, and data analytics in modern drug discovery. Explores blockchain, automation, and robotics as enablers of efficient and transparent pharmacy systems. Integrates computational modeling with experimental approaches for enhanced drug formulation and testing. Highlights 3D printing, telepharmacy, and RegTech as transformative tools in pharmaceutical innovation. Bridges classical pharmaceutical sciences with emerging digital and biotechnological advancements.

Microbial Insights into Wastewater Treatment and Environmental Sustainability examines the way microorganisms are reshaping the way we tackle environmental challenges, offering practical and science-driven strategies for wastewater remediation, pollution control, and resource recovery. Integrating microbiology, environmental science, and biotechnology, this volume reveals how microbial processes underpin sustainable solutions for ecosystem restoration and global environmental health. The book begins with foundational concepts, such as the microbial ecology of polluted sites and mechanisms of pollutant sequestration, to specialized topics including arsenic bioremediation, microbe-driven green nanotechnology, and biocontrol innovations. It further investigates plant-microbe partnerships that enhance environmental resilience, and explores cutting-edge molecular and biosensing techniques for real-time environmental monitoring. Case studies highlight the transition from laboratory research to field-scale applications, while forward-looking sections consider microbial nanotechnology for sustainable energy generation and microbial strategies for waste valorization. Key Features: Explains microbial roles in pollution mitigation and environmental recovery Demonstrates sequestration, bioremediation, and nanotechnology-based microbial innovations Integrates molecular tools and biosensors for environmental health assessment Applies microbial strategies to wastewater treatment, energy production, and waste management Highlights real-world case studies linking theory to practice Incorporates multidisciplinary insights from global research contributors Advances sustainable development through microbial resource recovery.

With pesticide overuse threatening ecosystems, food safety, and human health,Biological Control for Plant Protection: Recent Advances in Research and Sustainability addresses one of the most pressing challenges in modern agriculture, enhancing crop productivity while reducing reliance on chemical pesticides. Integrating scientific advances with practical strategies to support integrated pest, weed, and disease management systems, the book brings together contributions from leading researchers and academicians providing an up-to-date compilation of topics ranging from isolation, characterization, and mass rearing of natural enemies to the field application of botanicals and biological methods for biotic stress management in plants. Key Features: Explores cutting-edge biological control methods for pests, pathogens, and weeds. Highlights environmentally sustainable alternatives to chemical pesticides. Covers natural enemies, botanicals, and biofertilizers as components of integrated management. Presents case studies and research from diverse agroecosystems, including organic farming. Provides a comprehensive reference for researchers, practitioners, and policymakers.

Positioned at the crossroads of genomics, proteomics, artificial intelligence, and biomedical engineering, this book provides a roadmap for leveraging computational intelligence to address the complex challenges of modern life sciences, healthcare, and industrial biotechnology. Across twelve comprehensive chapters, the book lays the foundations for sequencing technologies, omics data, and the principles of biotechnology data management. It then transitions into the application of machine learning models ranging from neural networks to optimization frameworks to extract meaningful insights from large-scale biological datasets. Subsequently it addresses pressing challenges such as data noise, scalability, and ethical AI, while also highlighting algorithmic breakthroughs in pharmacogenomics, drug discovery, precision medicine, and synthetic biology. Case studies illustrate real-world applications, from CRISPR diagnostics and clinical trial optimization to agricultural genomics and biomedical engineering innovations. The closing chapters project the future trajectory of biotechnology, exploring quantum computing, federated learning, and secure data-sharing techniques. Key Features: Uncovers the revolutionary role of computational algorithms in biotechnology research and healthcare Explores the integration of AI, ML, and optimization methods in genomics, proteomics, and systems biology Analyzes real-world applications through case studies in pharmacogenomics, CRISPR, and agritech Provides practical insights into implementing secure, scalable, and ethical data solutions Gives an understanding future trends such as quantum computing and federated learning in biotech innovation.

Bridging the fields of pharmacy, biotechnology, dermatology, and cosmetic science, this book offers a multidisciplinary perspective on innovation, efficacy, and safety in the development of next-generation beauty and personal care products. The book discusses emerging technologies such as nanoformulations, artificial intelligence, gene therapy, personalized medicine, and peptide science. It addresses their transformative role in cosmetic product development-from skin and hair care to sun protection, anti-aging solutions, and mood-enhancing formulations. Readers will also gain insights into regulatory frameworks, clinical studies, and intellectual property considerations, making this a practical guide for both innovation and compliance in the beauty-tech space. Key Features: Explores integration of pharmaceutical techniques in cosmetic formulation Highlights nano-carriers, AI tools, and gene-based therapies in product development Details the role of natural and herbal ingredients in modern skin and hair care Covers peptide technologies for anti-aging and skin rejuvenation Addresses personalized medicine and pharmacogenomics in cosmetics Reviews regulatory challenges, clinical validation, and patent strategies

This book explores the complex interactions between plants and parasitic nematodes, with a particular focus on the natural chemical defenses plants deploy against these agricultural pests. As nematode infestations continue to cause major crop losses globally, this book addresses the urgent need for sustainable, eco-friendly alternatives to synthetic pesticides. The book comprises eight in-depth chapters, examining the biochemical and physiological roles of phytochemicals in plant defense, their biosynthesis, modes of action, and the influence of environmental conditions on their efficacy. It also assesses current challenges related to the application of these natural compounds in practical nematode control strategies. Drawing from advances in plant biology, molecular science, and agronomy, the book offers a consolidated view of recent developments in the field. Key features: Analyzes plant-nematode interaction dynamics Details classes and mechanisms of defense-related phytochemicals Explores biosynthetic pathways and environmental influences Examines potential for biopesticide development and integrated management Highlights research gaps and future directions.