Microneedles

Author(s): Yunhua Gao, Yuqin Qiu and Suohui Zhang

Pp: 210-259 (50)

* (Excluding Mailing and Handling)

Abstract

Transdermal drug delivery is a well-accepted route of administration for therapeutical drugs. Skin is the largest area human body organ, however, the substantial barrier property of the skin stratum corneum limits practical value of transdermal route of drug administration. It has been proved that microneedle array devices can overcome the barrier characteristics of the stratum corneum and enhance the delivery of therapeutic medicines through skin. This chapter focuses on looking at the microneedle-mediated transdermal drug delivery for therapeutical applications. The definition of microneedles, enhancement mechanisms and devices in research or in the market are also depicted.

Keywords: Definition, Devices in research or in the market, Mechanisims of action, Microneedle, Therapeutical applications.

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