The administration of drugs in the skin using ultrasound is recognized like sonophoresis. The ultrasound is dating back to the fifties for high frequency (HF) and low frequency (LF). It has been investigated over the past two decades. Clearly, the use of ultrasound to drug delivery (DD) recently gained importance, thereby increasing patents and new commercial devices.
This chapter shows the important findings in sonophoresis. Particular attention is focused into therapeutical applications including transdermal drug delivery (TDD), gene therapy, sport medicine and sonophoretic devices.
Keywords: Physical enhancers, Skin, Sonolysis, Sonophoresis, Sonophoretic devices, Sport medicine, Ultrasound.