Polarity Index in Proteins-A Bioinformatics Tool

Amyloid Proteins

Author(s): Carlos Polanco

Pp: 59-70 (12)

DOI: 10.2174/9781681082691116010012

* (Excluding Mailing and Handling)


This chapter describes the main results obtained when the polar profile of peptides associated to Amyloidosis is determined by polarity index method (Sect. 3.3), and the relation these peptides have with a group of proteins identified by their structure-function called natively folded proteins, partially folded proteins, and natively unfolded proteins. Amyloidosis is a term that groups a set of mental diseases with neurodegenerative characteristics, caused by the agglomeration of natively unfolded proteins on the neurons and lipoproteins. This chapter shows that the proteins that express neurons are natively folded proteins.

Keywords: Amyloid fibrils, Amyloidosis, Bacteria, Chylomicrons carry triglycerides, Fungi, High density lipoproteins, Intermediate density lipoproteins, Lipids, Lipoproteins, Low density lipoproteins, Natively folded proteins, Natively unfolded proteins, Neurodegenerative diseases, Neurons, Partially folded proteins, Polar profile, Polarity index method, Very low density lipoproteins, Virus.

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