Quassinoids are highly oxygenated triterpenes, which were isolated as bitter principles from the plants of Simaroubaceae family. Their synthesis has attracted much attention because of the wide spectrum of their biological properties. The most prevalent quassinoids have C-20 picrasane skeleton, some known as bruceolides as they were isolated from the genus Brucea, which showed marked antileukemic and antimalarial activities.
About this chapter
Cite this chapter as:Zhengming Guo, Suryanarayana Vangapandu, Robert William Sindelar, Larry Anthony Walker, Robert David Sindelar ;
Biologically Active Quassinoids and Their Chemistry: Potential Leads for Drug Design, Frontiers in Medicinal Chemistry (2009) 4: 285. https://doi.org/10.2174/978160805207310904010285
Bentham Science Publisher