The pandemic has trembled the world with the massive outbreak, leaving the
scientific fraternity in shambles. The SARS-CoV-2 strain took a heavy toll and led to
the death of millions of people. In late 2020, various mutated strains of the virus surged
the disease across the world. For the same, diverse methods were used around the globe
in search of precise medication against the pandemic. Despite vaccination for viral
disease prevention, the virus has spread without restraint, making the need for strong
antiviral drugs- a need of the hour. Several techniques were used for the fabrication of
a strong antiviral drug in different modes of remedies. Many countries utilized their
conventional therapeutic knowledge against the virus, which comprises the use of
indigenous phytochemicals with varied biological activities. The present review
includes the virology, epidemiology, and different therapeutic procedures practiced
globally to combat the viral disease and highlights different indigenous potent plants
with biological activities, such as antiviral, antipyretic, immunomodulatory and
antimicrobial. These plants are efficacious and can be explored further as prospective
remedies for many other maladies affecting the world.
Keywords: B.1.617, COVID-19, Coronavirus, Herbal Medicines, Indigenous Curatives, Lopinavir, Remdesivir, SARS-CoV-2, 2-deoxy-D-glucose, Traditional Medicines.