Abstract
Cancer is the second leading cause of death globally, in which factors, such
as tobacco, radiation, and obesity contribute to this alarming data. Among the available
pharmacotherapy, natural products, such as noscapine, have historical evidence in
treating this disease, showing promising results aimed at inhibiting tubulin. In this
context, this remarkable molecule has been tested as a conjugated drug in treating the
COVID-19 pandemic. In this chapter, we demonstrate noscapine structurally-related
compounds, analyzing them based on SAR studies, and discuss the most promising
results reported so far.
Keywords: Anti-cancer, Drug discovery, Noscapine-based, SAR analysis.
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Combinatorial Chemistry & High Throughput Screening
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