GPI Membrane Anchors – The Much Needed link

Surface Engineering of Biomembranes with GPI-Anchored Proteins and its Applications

Author(s): Christoph Metzner, Daniel F. Legler and John A. Dangerfield

Pp: 83-97 (15)

DOI: 10.2174/978160805123611001010083

* (Excluding Mailing and Handling)


This chapter covers the use of glycosylphosphatidylinositol (GPI)-anchored proteins for surface modification of diverse types of biomembrane covered entities ranging from viruses and virus-related particles (section 1), to cells (section 2) and other natural and engineered micro- and nano-scaled particles (section 3). The aim is to present and review state-of-the-art research in this area and to discuss the future direction of GPI painting technology relating to applications in research, biotechnology and biomedicine.

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