Therapeutic Anti-Parkinson's Role of Bacopa monnieri and Reconsideration of Underlying Mechanisms

 Neurodegeneration leads to several life-threatening brain disorders such as Parkinson’s disease, Alzheimer’s disease, and many more. Such kinds of diseases have a great impact on normal life patterning and may cause other severe symptoms, which are sometimes incurable. PD is the second most common disease characterized by the symptoms like Bradykinesia, resting tremor, postural instability, and some motor symptoms involving cognitive impairment and sleep disturbance. Memory plays a major role in sustaining the life of an individual. The development of an advanced molecular technique for treating PD increases day by day, but the complications in these techniques also cannot be ignored, so scientists move towards ayurvedic herbs to treat such kinds of disorders. Bacopa monneiri is an ayurvedic medicinal creeping plant used since ancient times to treat several kinds of diseases, including brain diseases. It has many components which are useful in neuroprotection and ameliorating PD. The core aim of the present chapter is to summarize and discuss how B. monnieri plays a therapeutic role in PD

Keywords: Alpha-synuclein, Antioxidant, B. monneiri, Nootropic herb, Oxidative stress, Parkinson’s disease.