The rising of chronic ailments impinged on humans worldwide has paved
the urgent need for newer therapeutic vital compounds that are biologically active and
have the capacity to endeavour without exerting any adverse or cytotoxic effects. This
necessitates extensive research to investigate unexplored natural sources for such
promising sources. A diverse array of fungi species has garnered considerable attention
over the past century due to the assortment of their opportunities to generate novel
active ingredients with multifunction mechanisms towards recuperative applications.
Some of the fungal bioactive compounds possess exclusive therapeutic potential and
pharmaceutical importance. These efficacious bioactive compounds including
Paclitaxel, Podophyllotoxin, Enniatins, Camptothecin, Ascophytatin with their
properties like anti-bacterial, antiviral, anti-parasitic, anti-diabetic, anti-cancerous,
immunomodulatory are discussed in this chapter.
Keywords: Endophytes, Topoisomerase, Karyokinetics, Anti malignant, Paclitaxel , Podophyllotoxin, Enniatins, Camptothecin, Ascophytatin.