Colloidosome as an Efficient Novel Drug Delivery System: An Update

Colloidosomes have been recognized as drug delivery systems with significant flexibilities. Colloidosomes are microcapsules having shells of fused coagulated particles, which are processed by the alignment of colloidal particles at the oil-water interface. They have adequate mechanical solidity, compatibility and are capable of encapsulating biologically sensitive materials such as hydrophilic medicines, insecticides, protein, and aroma and delivering them to the desired location. It displays a huge potential in controlled and sustained drug delivery of active constituents. The permeability and dimensions of colloidal particles need to be examined prudently. Colloidsomes can be diversely applied in several fields like protein delivery, gene delivery, targeting the brain and tumour. Many scientists have been delighted by the responsive colloidosomes' ability to successfully deliver drugs to the targeted site without causing any side effects, particularly anticancer drugs. Encapsulation of herbal drugs like curcumin, neem oil, quinine, etc., can also be achieved by colloidsomes. This chapter will cover the various techniques used for the development of colloidosomes and their classification like patchy colloidosomes, aqueous core colloidosomes, responsive colloidosomes, and coated colloidosomes, along with their application in drug delivery. 

Keywords: Colloidosomes, Core materials, Emulsion droplets, Responsive colloidosomes, Permeability, Microcapsules.