Bioremediation: Challenges and Advancements

Application of “OMICs” Approaches in Bioremediation

Author(s): Monika Sharma, Shagun Sharma, Shibnath Mazumder and Ram Krishan Negi *

Pp: 191-223 (33)

DOI: 10.2174/9789815036039122010010

* (Excluding Mailing and Handling)


Bioremediation is an eco-friendly and highly efficient technology over other
kinds of treatments to remediate contaminated sites. However, it is necessary to take
care of every parameter related to microbial diversity and physiology and the
metabolism of the microbes during bioremediation, which helps in determining the
efficiency and the key factors responsible for accelerating the decontamination process.
For this aspect, various OMICs approaches such as genomics, transcriptomics,
proteomics, and metabolomics play a significant role in generating the information
relevant to the degradation of the contaminants by the microbes. These approaches help
in studying the functional and bio-synthetic potential of a microbe in isolation and play
a crucial role in studying the functional potential of the community as a whole at a
contaminated site. Microbial diversity, an abundance of microbial genera, and their
enzymes are involved in the degradation of various types of pollutants in the
contaminated environment. The present chapter provides an overview of various
studies which are based on the application of OMICs in the field of bioremediation,
advancement in tools and technologies in the methodology associated with OMICS, as
well as about the key microbial players and enzymes used in the degradation of

Keywords: 2D SDS PAGE, Biodegradation, Bioremediation, De novo synthesis, Feature extraction, Fluxomics, Functional potential, Genomics, Herbicide, In silico omics, LC-MS analysis, Mass spectrometry, Metabolomics, Metagenomics, Metaproteomics, Metatranscriptomics, Microbial community, Microbial diversity, OMICs, Protein, Proteomics, RNA-seq, Sequencing technology, Spectral preprocessing, Transcriptomics.

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