Non-adherence and non-compliance to the course of psychiatric medications
affect the standard treatment plan of a patient. Inability to monitor the correct time and
dosage also results in lesser efficiency of the drug and its action mechanism. Factors
that may cause instability and non-compliance with the treatment plan are the possible
side effects of drugs or the ease of use. With technological advancements in the field of
drug delivery, transdermal patches, while Being non-invasive, ensure proper dosage
and delivery of drugs through the skin, minimizing the first-pass metabolism. This
review examines the existing literature, working mechanism, preclinical studies, and
advancements in the application of transdermal patches in psychotropic drugs and deaddiction
while evaluating various psychiatric disorders and comparing their efficacy
and remission rate concerning standard oral treatment. It also addresses the challenges,
drawbacks, and strategies required to increase its efficiency in clinical use.
Keywords: Affective Disorders, Transdermal Drug Delivery Systems,
Schizophrenia, Substance Abuse Disorders, Sumatriptan Iontophoretic patch.
