Nanomaterials exhibit some extraordinary features. These features are the
bases for their applications in different fields such as biomedical, pharmaceuticals,
communication, warfare, clothing, sports industries, automobiles, etc. Reports reflect
on their interactions with abiotic and biotic components of the environment. It is very
imperative to understand their interactions with biomolecules or related materials.
These investigations elaborate on their benefits and, damaging effects; these ascertain
their appropriate applications. The concerned reactants may be natural, organic, or
inorganic. Nanomaterials interact with components of an environment in a medium like
air or water, on the bases of their specific structure and functional groups. During such
interactions, the physiological and ecological parameters of the environment also play a
significant role. The physicochemical properties of nanomaterials and surface
functionalities are due to the specific modifications of the nanomaterials. The
hydrophobicity or hydrophilicity of nanomaterials influences their interactions between
them and the biological and ecological systems. This chapter deals with the behavior of
nanomaterials, parameters, and conditions related to their interaction in a biosystem.
Keywords: Absorption, Applications, Drug delivery Systems, Nanomaterials,
Physicochemical Properties, Plasmonic Nanoparticles, Scattering, Surface
Energy, Tissues Engineering.