Title:Speculative Considerations about Some Cardiology Enigmas
Volume: 13
Issue: 3
Author(s): Paulo Roberto Barbosa Evora*, Andre Schmidt, Livia Arcêncio and José Antonio Marin-Neto
Affiliation:
- Department of Surgery and Anatomy, Ribeirão Preto School of Medicine, University of São Paulo, Av. Bandeirantes, 3900 - Monte Alegre - CEP: 14049-900 Ribeirão Preto/SP,Brazil
Keywords:
Coronary artery disease, heart valve disease, controversies, cardiology enigmas, arteriosclerosis, atrial fibrillation.
Abstract: Background: Enigmas often lead to hypotheses and speculations. For this reason,
especially for the sake of the reader’s motivation, we opted for the plain discussion of some cardiology
enigmas.
Objective: The present text was aimed to discuss speculatively some cardiology enigmas.
Method: Text was freely designed in the context of coronary artery and heart valve diseases.
Results: The results were presented as the combination enigma/hypothesis. 1) The absence of
arteriosclerosis in intramyocardial coronary arteries/ endothelium-myocardial interaction (crosstalk);
2) The unique and always confirmed superior evolution of the internal thoracic artery as coronary
graft/ higher NO basal release 3) The prophylactic left internal thoracic artery graft in mildlystenosed
coronary lesions/need of more accurate functional imaging techniques; 4) The high
incidence of perioperative atrial fibrillation in patients with coronary artery disease/atrial ischemia
associated to left circumflex coronary lesions; 5) The handling of disease-free saphenous vein grafts
at the time of reoperation/biological serendipity with graft vein segments; 6) The possible aortic
stenosis protection against coronary artery disease/ endothelium-myocardium interaction (crosstalk)
improving NO release.
Conclusion: The discussed topics associated with their respective speculative hypothesis remain as
enigmas, but would become motivations for investigations
