Aims: We correlate ultrasound, MRI, and clinical findings in neonates with suspected hypoxic ischemic injury.
Background: Recent advances in neuroimaging have led to improved detection of subtle insults associated with neurodevelopmental outcomes, beyond more historically described lesions such as large hemorrhages and hydrocephalus.
Objective: In this study, we compare cranial ultrasound to MRI for the evaluation of suspected HIE in preterm infants.
Methods: 147 premature infant patients with paired ultrasound and MRI exams were retrospectively analyzed to compare imaging finding accuracy and clinical value.
Result: We confirm that ultrasound is highly sensitive and specific for hydrocephalus, ventricular prominence, and gross structural abnormalities. Ultrasound is not a substitute for MRI in cases of small hemorrhages or white matter injury, however, certain US findings were associated with Apgar score and MRI sequelae of HIE.
Conclusion: Choosing between ultrasound and MRI for preterm neonates at risk for intracranial abnormalities based on their strengths can reduce cost and maximize clinical utility. MRI provides a highly sensitive identification of subtle brain injury, yet ultrasound is correlated with the peripartum clinical picture as measured by Apgar score.
[http://dx.doi.org/10.1136/archdischild-2014-306129] [PMID: 25637006]
[http://dx.doi.org/10.1016/j.neurad.2012.03.006] [PMID: 22633043]
[http://dx.doi.org/10.1007/s00431-019-03388-7] [PMID: 31065842]