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CNS & Neurological Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Review Article

An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease

Author(s): Rohit Kumar Verma*, Manisha Pandey, Pooja Chawla*, Hira Choudhury, Jayashree Mayuren, Subrat Kumar Bhattamisra, Bapi Gorain, Maria Abdul Ghafoor Raja, Muhammad Wahab Amjad and Syed Obaidur Rahman

Volume 21, Issue 10, 2022

Published on: 11 May, 2021

Page: [901 - 912] Pages: 12

DOI: 10.2174/1871527320666210512014505

Price: $65

Abstract

Background: The complication of Alzheimer’s disease (AD) has made the development of its therapeutic a challenging task. Even after decades of research, we have achieved no more than a few years of symptomatic relief. The inability to diagnose the disease early is the major hurdle behind its treatment. Several studies have aimed to identify potential biomarkers that can be detected in body fluids (CSF, blood, urine, etc.) or assessed by neuroimaging (i.e., PET and MRI). However, the clinical implementation of these biomarkers is incomplete as they cannot be validated.

Methods: This study aimed to overcome the limitation of using artificial intelligence along with technical tools that have been extensively investigated for AD diagnosis. For developing a promising artificial intelligence strategy that can diagnose AD early, it is critical to supervise neuropsychological outcomes and imaging-based readouts with a proper clinical review.

Conclusion: Profound knowledge, a large data pool, and detailed investigations are required for the successful implementation of this tool. This review will enlighten various aspects of early diagnosis of AD using artificial intelligence.

Keywords: Alzheimer’s disease, artificial intelligence, biomarkers, algorithms, AD diagnosis, PET.

Graphical Abstract
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