Epigenetic Mechanisms in Human Diseases and Gene Therapy
Epigenetic mechanisms, including DNA methylation, histone post-translational modifications, non-coding RNAs, and chromatin remodeling, play crucial roles in gene expression. Aberrant epigenetic changes are often correlated with human diseases and metabolic disorders. Since gene expression can be activated/inactivated by reversible epigenetic mechanisms, increasing studies have focused on epigenetic regulation in gene ...read more
