Abstract
Background: Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.
Objectives: This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.
Keywords: Ginsenoside Rg3, Anticancer, Important cellular functions, Epigenetic pathways, Important pathways, Combination therapies.
Current Topics in Medicinal Chemistry
Title:Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications
Volume: 24 Issue: 10
Author(s): Lei Wu, Lin Bai, Wenshu Dai, Yaping Wu, Pengjun Xi, Jie Zhang and Lily Zheng*
Affiliation:
- TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, Sichuan Province, China
- Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu 610041, China
Keywords: Ginsenoside Rg3, Anticancer, Important cellular functions, Epigenetic pathways, Important pathways, Combination therapies.
Abstract:
Background: Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.
Objectives: This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.
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Cite this article as:
Wu Lei, Bai Lin, Dai Wenshu, Wu Yaping, Xi Pengjun, Zhang Jie and Zheng Lily*, Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications, Current Topics in Medicinal Chemistry 2024; 24 (10) . https://dx.doi.org/10.2174/0115680266283661240226052054
DOI https://dx.doi.org/10.2174/0115680266283661240226052054 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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