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DOI: 10.2174/97816080518301120101 eISBN: 978-1-60805-183-0, 2012 ISBN: 978-1-60805-502-9
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For Books Teodorico C. Ramalho , " Chemoinformatics: Directions Toward Combating Neglected Diseases ", Bentham Science Publishers (2012). https://doi.org/10.2174/97816080518301120101
Print ISBN978-1-60805-502-9
Online ISBN978-1-60805-183-0
Page: i-i (1) Author: Tanox Celmar Costa França DOI: 10.2174/97816080518301120101000i
Page: ii-ii (1) Author: Teodorico C. Ramalho, Matheus P. Freitas and Elaine F.F. da Cunha DOI: 10.2174/9781608051830112010100ii
Page: iii-iii (1) Author: Teodorico C. Ramalho, Matheus P. Freitas and Elaine F.F. da Cunha DOI: 10.2174/978160805183011201010iii
Page: 3-32 (30) Author: Elaine F.F. da Cunha, Teodorico C. Ramalho, Daiana T. Mancini and Matheus P. Freitas DOI: 10.2174/978160805183011201010003 PDF Price: $15
Page: 33-48 (16) Author: Alicia Ponte-Sucre, Emilia Díaz and Maritza Padrón-Nieves DOI: 10.2174/978160805183011201010033 PDF Price: $15
Page: 49-68 (20) Author: Tanos C.C. França and Magdalena N. Rennó DOI: 10.2174/978160805183011201010049 PDF Price: $15
Page: 69-128 (60) Author: Mushtaque S. Shaikh, Vijay M. Khedkar and Evans C. Coutinho DOI: 10.2174/978160805183011201010069 PDF Price: $15
Page: 129-144 (16) Author: Tanos Celmar Costa França and Alan Wilter Sousa da Silva DOI: 10.2174/978160805183011201010129 PDF Price: $15
Page: 145-153 (9) Author: Adriana de Oliveira Gomes, Alessandra Mendonça Teles de Souza, Alice Maria Rolim Bernardino, Helena Carla Castro and Carlos Rangel Rodrigues DOI: 10.2174/978160805183011201010145 PDF Price: $15
Page: 154-161 (8) Author: Matheus P. Freitas, Teodorico C. Ramalho, Elaine F. F. da Cunha and Rodrigo A. Cormanich DOI: 10.2174/978160805183011201010154 PDF Price: $15
Page: 162-173 (12) Author: Daiana Teixeira Mancini, Elaine F. F. da Cunha, Teodorico C. Ramalho and Matheus P. Freitas DOI: 10.2174/978160805183011201010162 PDF Price: $15
Page: 174-196 (23) Author: Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva DOI: 10.2174/978160805183011201010174 PDF Price: $15
Page: 197-199 (3) Author: Teodorico C. Ramalho, Matheus P. Freitas and F. F. da Cunha Elaine DOI: 10.2174/978160805183011201010197
Low-income populations in developing regions of Africa, Asia and the Americas have been particularly injured by a group of tropical infections denominated neglected diseases. Compared to important illnesses, neglected diseases do not enjoy significant research funding and are not considerably important targets for the “Big Pharma” ventures in terms of development of new drugs, though these infections can make widespread diseases like AIDS more deadly. Despite affecting millions of people around the world, causing many deaths and having a significant limiting influence on the quality of life of affected people, the selection of new molecular targets and the development of more efficient drugs against those diseases is scarce. Furthermore, little detailed computational work on this subject has appeared. It should be kept in mind, however, that computers are an essential tool in modern medicinal chemistry. Currently, these powerful computational tools allow one to obtain insights on the interaction between enzyme-substrate, reaction mechanisms, statistical behavior of molecules and much more, at the molecular level, contributing significantly to solve problems in biological systems. Chemoinformatics: Directions Toward Combating Neglected Diseases explores an open problem in academic literature with a stimulating discussion on the state of the art knowledge in this important research field with respect to neglected diseases, pointing out perspectives on using molecular modeling and theoretical approaches. This eBook is a handy reference guide for anyone who is interested in or deals with medicinal chemistry focused on neglected diseases, from students to advanced researchers.
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