Cell Biology: Basics to Breakthroughs

Prokaryotes vs. Eukaryotes: Comparative Structural and Functional Insights

Author(s): Kruthika Prakash, Sayantani Chattopadhyay, T. Sasitharan, Soumyadeep Maiti, Sanjana Dhayalan, K. Kumaran, R. Kirubakaran* and K. N. Aruljothi

Pp: 20-33 (14)

DOI: 10.2174/9798898812430125010006

* (Excluding Mailing and Handling)

Abstract

Organisms are fundamentally divided into prokaryotes and eukaryotes, except for viruses. Further classifications are depicted in various classifications, among which the most recent one is Whittaker’s classification. Prokaryotes, the primitive organisms, gave rise to eukaryotes, and this transformation led to simple single-celled organisms evolving into colonies and multicellular cells. Prokaryotic cells, which include bacteria and archaea, exhibit diverse metabolic processes such as autotrophy and heterotrophy. In contrast, eukaryotic cells are characterized by the presence of a well-defined nucleus and membrane-bound organelles, unlike prokaryotic cells. In contrast, eukaryotes developed around 2 billion years ago and possess complex cellular structures, including a well-defined nucleus and various organelles, such as mitochondria and chloroplasts. The transition from unicellular to multicellular life is a significant evolutionary milestone that involves various adaptations and mechanisms, including cell-to-cell communication, adhesion, and coordinated growth. Genetic conservation and epigenetic mechanisms play pivotal roles in the development of multicellular structures, as demonstrated in organisms like fungi and metazoans. Eukaryotic cells, such as those from yeast and mammalian sources, are pivotal in biotechnological applications, including the production of recombinant proteins and gene therapy. Their ability to properly fold and process proteins allows for the creation of functional biopharmaceuticals and vaccines that simulate pathogen structures to invoke robust immune responses. Notable eukaryotic microorganisms like algae and fungi are also increasingly recognized for their potential in sustainable biofuel production. Since genes serve as the backbone for almost all cells, they can be manipulated to be more user-friendly.


Keywords: Biofuel production, Characteristics, Eukaryotes, Evolution, Evolutionary biology, Gene therapy, Genes, Multicellularity, Prokaryotes, Recombinant proteins, Whittaker’s classification.