The proposed book chapter aims to present a comprehensive review of nanomaterial-based biosensors utilizing field-effect transistors (FETs), exploring their diverse applications, advancements, and future potentials. The focus will be on examining the integration of carbon-based nanomaterials into FET-based biosensors and their role in revolutionizing biosensing technologies. Field effect-based biosensors (BioFETs) stand out among other biosensing technologies due to their unique features such as real-time screening, ultrasensitive detection, low cost, and amenability to extreme device miniaturization due to the convenient utilization of nanoscale materials. FETbased sensors operate on the principle that changes in the surrounding environment, such as alterations in temperature, pressure, gas concentration, or biological elements, modulate the electrical characteristics of the transistor. The integration of carbon-based nanomaterials into biosensing applications has emerged as a transformative development, significantly augmenting the efficacy and sensitivity of detection devices, particularly within the domain of field-effect transistor (FET) based technologies. The intent is to provide a holistic view of how these advancements have contributed to improving detection capabilities and to outline potential avenues for further research and applications in the field of biosensing.
Keywords: Bio-FETs, Biosensors, Biomolecules, Carbon nanotubes.
