Quinones: A Privileged Moiety for Drug Discovery

Identification Techniques of Natural and Synthetic Quinones Using Various Methods

Author(s): Satyanarayana Battula* and Ashutosh Kumar Dash

Pp: 52-63 (12)

DOI: 10.2174/9798898810276125010005

* (Excluding Mailing and Handling)

Abstract

 Quinones are intriguing substances with distinctive properties and several significant biological and chemical functions and applications. Quinones are found in many parts of nature, including the tissues of plants and animals. They have several important roles in biological systems, for example, in the electron transport process to preserve plants' and animals' biological processes, in the form of plastoquinone and phylloquinone to be a part of photosynthesis in plants, and in the posttranslational modification of proteins and others. On essentiality grounds, they need to be detected and determined from the natural and synthetic samples. This chapter incorporates the detection and determination methods for various natural and synthetic quinones, viz., titrimetric methods, spectrophotometric methods, HPLC-based methods, and GC-M- -based methods.


Keywords: GC-MS, HPLC, Titrimetric methods, Quinones.