Multicomponent reactions (MCRs) provide a unique way to incorporate the
structural attributes of three or more reactants in a single operation. Along with their
operational simplicity and synthetic convergence, MCRs are generally atom, step, and
time economical than comparable multistep processes. On the other hand, ionic liquids
(ILs) are salts with low melting points. Because of their low vapor pressure,
recyclability, and tunability, ILs offer a task-specific alternative to commonly
employed organic solvents. Thus, merging both strategies (MCRs & ILs) together
opens the way to a plethora of possibilities for greener productions of heterocyclic
compounds. In the proposed chapter, attempts will be made to cover the MCRs relevant
to heterocyclic synthesis conducted in ionic liquids (ILs) with a special emphasis on
process sustainability.
Keywords: Brønsted acid ionic liquids, Designer ionic liquid, Green chemistry, Heterocyclic synthesis, Ionic liquids, Multicomponent reactions, Polymeric ionic liquid, Room temperature ionic liquids, Task-specific ionic liquids.
