The chemistry of glycals and their derivatives has emerged as a hot topic in
carbohydrate chemistry owing to their incredible applications in biological and
medicinal chemistry. Annulated and C-2-branched sugars derived from glycal moiety
and its derivative have received immense attention. Herein, we have incorporated the
current advancement in the synthesis of 2-C-branched sugars and annulated sugars
derived from glycals, 2-haloglycals, and 2-nitroglycals using various synthetic
strategies, including C-H activation, 1,2-annulation, and cyclopropanation.
Keywords: C-H activation, Cyclopropanation, Glycals, Glycosides, 1, 2- Annulation, 2-Haloglycals.
