Among the various types of skin cancer, melanoma is the most aggressive
one, and the occurrences are rising rapidly throughout the universe. The early diagnosis
rate of melanoma skin cancer is around 14-15%, which hasa survival rate of less than 5
years. Conventional medicines are unable to treat it completely, resulting in the
destruction of healthy cells. Similarly, radiotherapy and chemotherapy have limitations
of higher toxicity, multi-drug resistance, and minimal survival rates even after the
treatment. The lipid-based nanoparticles are highly effective in the therapy of
melanoma skin cancer only after the prompt diagnosis. The current book chapter
signifies the applications of the advanced nanocarriers utilized for the diagnosis and
therapy of skin cancer. These advanced nanocarriers are classified as polymer-based
approaches (micelle, dendrimer, and hydrogels) and offer additional benefits like
targeted action, controlled delivery, longer circulation time, and high loading
efficiency. Nanoparticle-based approaches (organic and inorganic nanoparticles) and
carbon-based approaches (nanotubes, graphene oxide) are widely utilized for
possessing biosensing and diagnostic properties.
Keywords: Carbon nanotubes, Dendrimers, Graphene oxide, Hydrogels, Melanoma, Nanoparticles, Nanocarriers, Polymeric micelle, Skin cancer, Theranostics.
