The prevalence of cardiovascular disease (CVD) in patients with chronic
kidney disease (CKD) varies depending on the presence of traditional coronary artery
disease (CAD) risk factors, and is as high as 85% in the long-standing diabetic patient
on hemodialysis that is over the age of 45. This highly elevated risk necessitates timely
assessment and therapeutic interventions to mitigate the complications of CAD that
remain the most common cause of mortality in the patient with CKD. With the
overlapping risk factors and multifactorial causes of CAD seen in patients with CKD
such as diabetes, hyperlipidemia, and obesity, clinicians need to maintain a high index
of awareness of the proper evaluation and management tools and principles in their
armamentarium of care for these patients. In this chapter, we examine the current
evaluations and management principles and discuss their therapeutic implications.
Keywords: Cardiovascular disease, Chronic kidney disease, Evaluation,
Management.