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Mini-Reviews in Medicinal Chemistry

Volume 19, 20 Issues, 2019
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

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  • 28th of 59 in

    Chemistry, Medicinal

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Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

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Volume 19

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Number 10



Biography   Open Access



Review Article



Review Article



Review Article



Review Article



Research Article

Synthesis and Molecular Docking of New Thiophene Derivatives as Lactate Dehydrogenase-A Inhibitors

, 19(10): 833 - 841

Abd El-Galil E. Amr*, Mohamed F. El-Shehry, Alhussein A. Ibrahim, Hanaa M. Hosni, Mohamed A. Al-Omar and Hazem A. Ghabbour


DOI: 10.2174/1389557519666190212165302


Research Article

Ultrasound Assisted Synthesis of 3-(het)aryl Isocoumarin Derivatives and their in vitro Pharmacological Evaluation

, 19(10): 842 - 850

Gutta Lakshmi Prasanna, V.D. Nagendra Kumar Abbaraju, Yarlagadda Bharath, Mandava V. Basaveswara Rao* and Manojit Pal*


DOI: 10.2174/1389557519666190130163708


Research Article



Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 12


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 11


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



Recent Advances Towards Treatment of HIV: Synthesis and SAR Studies


Neelima Shrivastava, Asif Husain, Mohammad Rashid*, Shahid Karim, Nimer Fehaid Alsabeelah and Nasir Ali Siddiqui


View Abstract View on PubMed



Recent Advances in Apoptosis: THE Role of Hydrazones


Pelin Çıkla-Süzgün and Ş. Güniz Küçükgüzel*


View Abstract View on PubMed


Malaria Hybrids: A Chronological Evolution


Akranth Marella*, Garima Verma, Md. Shaquiquzzaman, Md. Faraz Khan, Wasim Akhtar and Md. Mumtaz Alam*


View Abstract View on PubMed


Synthesis, Docking Studies into CDK-2 and Anticancer Activity of New Derivatives Based Pyrimidine Scaffold and Their Derived Glycosides


Adel A. H. Abdel Rahman, Ibrahim F. Nassar*, Amira K. F. Shaban, Dina S. EL-Kady, Hanem M. Awad and Wael A. El Sayed


View Abstract View on PubMed


Human Galectin-1 and Its Inhibitors: Privileged Target for Cancer and HIV


Narella Sridhar Goud, P. S. Lakshmi Soukya, Mahammad Ghouse, Daipule Komal, Ravi Alvala and Mallika Alvala*


View Abstract View on PubMed



Protective Role of Natural Products in Cisplatin-Induced Nephrotoxicity


Nurul Raudzah Adib Ridzuan, Norhashima Abd Rashid, Faizah Othman, Siti Balkis Budin, Farida Hussan and Seong Lin Teoh*


View Abstract View on PubMed


Abstracts Ahead of Print


Synthesis of Azoloquinazolines and substituted benzothiazepine as antimicrobial agents


Asmaa F. Kassem, Fatimah Alshehrei, Eman M. H. Abbas and Thoraya A. Farghaly*


View Abstract


PPAR Ligands Containing Stilbene Scaffold


Marialuigia Fantacuzzi, Barbara De Filippis*, Rosa Amoroso and Letizia Giampietro


View Abstract


Spinacia oleracea Linn Considered as one of the Most Perfect Foods: an Pharmacological and Phytochemical Review


Rosa Martha Perez Gutierrez*, Elisa Gutierrez Velazquez and Silvia Patricia Paredes Carrera


View Abstract




Therapeutic Potential of Vanillin and its Main Metabolites to Regulate the Inflammatory Response and Oxidative Stress


Carlos S. M. Bezerra-Filho, Joice N. Barboza, Marilia T. S. Souza, Peter Sabry, Nasser S. M. Ismail and Damião P. de Sousa*


View Abstract



Potentials of Diphenyl Ether Scaffold as a Therapeutic Agent: A Review


Suvarna G Kini*, Ekta Rathi, Avinash Kumar and Varadaraj Bhat


View Abstract


Published Contents

Editor's Choice

Non-adenosine Nucleoside Inosine, Guanosine and Uridine as Promising Antiepileptic Drugs: a Summary of Current Literature

, 2014; 14(13): 1033 - 1042

Zsolt Kovacs, Katalin A. Kekesi, Gabor Juhasz, Janos Barna, Laszlo Heja, Renata Lakatos and Arpad Dobolyi


DOI: 10.2174/1389557514666141107120226



Combined Cancer Therapy with Non-Conventional Drugs: All Roads Lead to AMPK

, 2014; 14(8): 642 - 654

Suning Chen, Xingmei Zhu, Xiaofeng Lai, Tian Xiao, Aidong Wen and Jian Zhang


DOI: 10.2174/1389557514666140820104444



Antiaging Therapy: A Novel Target for Antilipolytic Drugs

, 2014; 14(7): 551 - 556

Gabriella Cavallini, Alessio Donati and Ettore Bergamini


DOI: 10.2174/1389557514666140622205540



Application of BRET for Studying G Protein-Coupled Receptors

, 2014; 14(5): 411 - 425

Agnieszka A. Kaczor, Magdalena Makarska-Bialokoz, Jana Selent, Rocio A. de la Fuente, Maria Marti-Solano and Marian Castro


DOI: 10.2174/1389557514666140428113708



Open Access Articles

Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng





G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek





Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic








Most Cited Articles

Review Article

An overview on application of natural substances incorporated with electrospun nanofibrous scaffolds to development of innovative wound dressings

, 2018; 18(5): 414-427.

Younes Pilehvar-Soltanahmadi, Mehdi Dadashpour, Abbas Mohajeri, Amir Fattahi, Roghayeh Sheervalilou and Nosratollah Zarghami*


DOI: 10.2174/1389557517666170308112147


Review Article

Advance in anti-tumor mechanisms of shikonin, alkannin and their derivatives

, 2018; 18(2): 164-172.

Xu Zhang, Jia-Hua Cui, Qing-Qing Meng, Shao-Shun Li, Wen Zhou* and Sui Xiao*


DOI: 10.2174/1389557517666170228114809


Review Article

Synthetic and natural lipase inhibitors

, 2018; 18(8): 672-683.

Ewa Bialecka-Florjanczyk*, Agata Urszula Fabiszewska, Jolanta Krzyczkowska and Alina Kurylowicz


DOI: 10.2174/1389557516666160630123356


Review Article

Quinoxalinone as a privileged platform in drug development

, 2018; 18(5): 392-413.

Leilei Shi, Wei Hu, Jifeng Wu, Huaiyu Zhou, Hua Zhou and Xun Li*


DOI: 10.2174/1389557517666171101111134



Review Article

Recent advances on 3-hydroxyflavone derivatives: Structures and properties

, 2018; 18(2): 98-103.

Burcu Butun, Gulacti Topcu and Turan Ozturk*


DOI: 10.2174/1389557517666170425102827



Review Article

Berberine derivatives with different pharmacological activities via structural modifications

, 2018; 18(17): 1424-1441.

Daipeng Xiao, Zhenbao Liu, Shanshan Zhang, Mi Zhou, Fen He, Ming Zou, Junying Peng, Xiong Xie, Yanfei Liu* and Dongming Peng*


DOI: 10.2174/1389557517666170321103139




Review Article

The synthetic and biological attributes of pyrazole derivatives: A review

, 2018; 18(11): 918-947.

Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh


DOI: 10.2174/1389557517666170927160919


Review Article

Rubiscolins - Highly potent peptides derived from plant proteins

, 2018; 18(2): 104-112.

Renata Perlikowska* and Anna Janecka


DOI: 10.2174/1389557517666170426160703



Review Article

Ellagitannins: Bioavailability, purification and biotechnological degradation

, 2018; 18(15): 1244-1252.

Pedro Aguilar-Zarate, Jorge E. Wong-Paz, Juan J. Buenrostro-Figueroa, Juan A. Ascacio, Juan C. Contreras-Esquivel and Cristóbal N. Aguilar*


DOI: 10.2174/1389557517666170208144742


Review Article

Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview

, 2018; 18(17): 1479-1485.

Burak Yulug*, Lutfu Hanoglu, Elmir Khanmammadov, Ozge Arici Duz, Burcu Polat, Taha Hanoglu, Mehmet Yalcin Gunal and Ertugrul Kilic


DOI: 10.2174/1389557517666170927162537



Most Accessed Articles

Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

, 2016; 16(2): 120-162.

Ajmer Singh Grewal, Shashikant Bhardwaj, Deepti Pandita, Viney Lather and Bhupinder Singh Sekhon


DOI: 10.2174/1389557515666150909143737




Molecular Targets, Anti-cancer Properties and Potency of Synthetic Indole-3-carbinol Derivatives

, 2019; 19(7): 540-554.

Mojgan Noroozi Karimabad, Mehdi Mahmoodi, Abdolah Jafarzadeh, Ali Darekordi, Mohamad Reza Hajizadeh and Gholamhossein Hassanshahi*


DOI: 10.2174/1389557518666181116120145





The Relationship between Pharmacological Properties and Structure- Activity of Chrysin Derivatives

, 2019; 19(7): 555-568.

Yang Li, Yan-peng Li, Jun He*, Ding Liu, Qi-zhi Zhang, Kang Li, Xing Zheng, Guo-Tao Tang, Yu Guo and Yunmei Liu*


DOI: 10.2174/1389557518666180424094821




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