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Mini-Reviews in Medicinal Chemistry

Volume 19, 20 Issues, 2019
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

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  • 28th of 59 in

    Chemistry, Medicinal

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Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

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Volume 19

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Number 8



Biography   Open Access



Review Article



Review Article

Biological Effects of Licochalcones

, 19(8): 647 - 656

Gatta Daniela Maria Pia, Franceschelli Sara, Felaco Mario and Speranza Lorenza*


DOI: 10.2174/1389557518666180601095420


Research Article



Research Article



Research Article



Research Article

Drug Design of Inhibitors of Alzheimer’s Disease (AD): POM and DFT Analyses of Cholinesterase Inhibitory Activity of β-amino di-Carbonyl Derivatives

, 19(8): 688 - 705

Taibi Ben Hadda*, Abdur Rauf, Hsaine Zgou, Fatma Sezer Senol, Ilkay Erdogan Orhan, Yahia Nasser Mabkhot*, Ismail I. Althagafi, Thoraya A. Farghaly* and Seham Alterary


DOI: 10.2174/1389557518666181102102816


Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Analysis of the Essential Oils of Five Artemisia Species and Evaluation of their Cytotoxic and Proapoptotic Effects


Zahra Tayarani-Najaran, Maryam Akaberi, Bahareh Hassanzadeh, Nazila Shirazi, Javad Asili, Hadi Al-Najjar, Amirhossein Sahebkar* and Seyed Ahmad Emami*


View Abstract View on PubMed


Human Galectin-1 and Its Inhibitors: Privileged Target for Cancer and HIV


Narella Sridhar Goud, P. S. Lakshmi Soukya, Mahammad Ghouse, Daipule Komal, Ravi Alvala and Mallika Alvala*


View Abstract View on PubMed



Protective Role of Natural Products in Cisplatin-Induced Nephrotoxicity


Nurul Raudzah Adib Ridzuan, Norhashima Abd Rashid, Faizah Othman, Siti Balkis Budin, Farida Hussan and Seong Lin Teoh*


View Abstract View on PubMed



Synthesis of Novel Bis-pyrazole Derivatives as Antimicrobial Agents


Zeinab A. Muhammad, Fatimah Alshehrei, Mohie E. M. Zayed, Thoraya A. Farghaly* and Magda A. Abdallah


View Abstract View on PubMed


Scaffold Based Search on the Desferithiocin Archetype


Mousumi Shyam, Abhimanyu Dev, Barij Nayan Sinha and Venkatesan Jayaprakash*


View Abstract View on PubMed


Pharmacophores Modeling in Terms of Prediction of Theoretical Physicochemical Properties and Verification by EXPERIMENTAL correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors


Vladimir Amirkhanov, Abdur Rauf, Taibi Ben Hadda, Vladimir Ovchynnikov, Viktor Trush, Muhammad Saleem, Muslam Raza, Tayyeba Rehman, Hsaine Zgou, Usama Shaheen and Thoraya Farghaly*


View Abstract View on PubMed


Pharmacological Aspects and Potential Use of Phloretin: A Systemic Review


Arokia Vijaya Anand Mariadoss*, Ramachandran Vinyagam, Vinothkumar Rajamanickam, Vijayalakshmi Senthilkumar, Sathish Venkatesan and Ernest David*


View Abstract View on PubMed



Abstracts Ahead of Print

Recent advances in apoptosis: The role of hydrazones


Pelin Çıkla-Süzgün and Ş. Güniz Küçükgüzel*


View Abstract



Recent Advances towards Treatment of HIV: Synthesis and SAR Studies


Neelima Shrivastava, Asif Husain, Mohammad Rashid*, Shahid Karim, Nimer Fehaid Alsabeelah and Nasir Ali Siddiqui


View Abstract


Malaria Hybrids: A Chronological Evolution


Akranth Marella*, Garima Verma, Md. Shaquiquzzaman, Md. Faraz Khan, Wasim Akhtar and Md. Mumtaz Alam*


View Abstract


Synthesis, Docking Studies into CDK-2 and Anticancer Activity of New Derivatives Based Pyrimidine Scaffold and Their Derived Glycosides


Adel A. H. Abdel Rahman, Ibrahim F. Nassar*, Amira K. F. Shaban, Dina S. EL-Kady, Hanem M. Awad and Wael A. El Sayed


View Abstract


Therapeutic Potential of Vanillin and its Main Metabolites to Regulate the Inflammatory Response and Oxidative Stress


Carlos S. M. Bezerra-Filho, Joice N. Barboza, Marilia T. S. Souza, Peter Sabry, Nasser S. M. Ismail and Damião P. de Sousa*


View Abstract




Potentials of Diphenyl Ether Scaffold as a Therapeutic Agent: A Review


Suvarna G Kini*, Ekta Rathi, Avinash Kumar and Varadaraj Bhat


View Abstract



Editor's Choice

Non-adenosine Nucleoside Inosine, Guanosine and Uridine as Promising Antiepileptic Drugs: a Summary of Current Literature

, 2014; 14(13): 1033 - 1042

Zsolt Kovacs, Katalin A. Kekesi, Gabor Juhasz, Janos Barna, Laszlo Heja, Renata Lakatos and Arpad Dobolyi


DOI: 10.2174/1389557514666141107120226



Combined Cancer Therapy with Non-Conventional Drugs: All Roads Lead to AMPK

, 2014; 14(8): 642 - 654

Suning Chen, Xingmei Zhu, Xiaofeng Lai, Tian Xiao, Aidong Wen and Jian Zhang


DOI: 10.2174/1389557514666140820104444



Antiaging Therapy: A Novel Target for Antilipolytic Drugs

, 2014; 14(7): 551 - 556

Gabriella Cavallini, Alessio Donati and Ettore Bergamini


DOI: 10.2174/1389557514666140622205540



Application of BRET for Studying G Protein-Coupled Receptors

, 2014; 14(5): 411 - 425

Agnieszka A. Kaczor, Magdalena Makarska-Bialokoz, Jana Selent, Rocio A. de la Fuente, Maria Marti-Solano and Marian Castro


DOI: 10.2174/1389557514666140428113708



Open Access Articles

Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng





G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek





Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic








Most Cited Articles


Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

, 2016; 16(2): 120-162.

Ajmer Singh Grewal, Shashikant Bhardwaj, Deepti Pandita, Viney Lather and Bhupinder Singh Sekhon


DOI: 10.2174/1389557515666150909143737


Carbazole derivatives: a promising scenario for breast cancer treatment

, 2016; 16(8): 630-643.

Anna Caruso, Domenico Iacopetta, Francesco Puoci, Anna Rita Cappello, Carmela Saturnino and Maria Stefania Sinicropi


DOI: 10.2174/1389557515666150709111342


New Progress in Azole Compounds as Antimicrobial Agents

, 2017; 17(2): 122-166.

Hui-Zhen Zhang, Lin-Ling Gan, Hui Wang and Cheng-He Zhou


DOI: 10.2174/1389557516666160630120725


Importance and Implications of the Production of Phenolic Secondary Metabolites by Endophytic Fungi: A Mini-Review

, 2016; 16(4): 259-271.

Patrícia Lunardelli Negreiros de Carvalho, Eliane de Oliveira Silva, Daniela Aparecida Chagas-Paula, Jaine Honorata Hortolan Luiz and Masaharu Ikegaki


DOI: 10.2174/1389557515666151016123923



Therapeutic Impact of Sphingosine 1-phosphate Receptor Signaling in Multiple Sclerosis

, 2016; 16(7): 547-554.

Kristina Candido, Henry Soufi, Mausumi Bandyopadhyay and Subhajit Dasgupta


DOI: 10.2174/1389557515666150709122517


Phytochemicals for the Management of Melanoma

, 2016; 16(12): 953-979.

Harish Chandra Pal, Katherine Marchiony Hunt, Ariana Diamond, Craig A. Elmets and Farrukh Afaq


DOI: 10.2174/1389557516666160211120157



Review on EGFR Inhibitors: Critical Updates

, 2016; 16(14): 1134-1166.

Davinder Singh, Bhupinder Kumar Attri, Rupinder Kaur Gill and Jitender Bariwal


DOI: 10.2174/1389557516666160321114917



Most Accessed Articles

Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

, 2016; 16(2): 120-162.

Ajmer Singh Grewal, Shashikant Bhardwaj, Deepti Pandita, Viney Lather and Bhupinder Singh Sekhon


DOI: 10.2174/1389557515666150909143737



Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684-1701.

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*


DOI: 10.2174/1389557518666180516163539






Molecular Targets, Anti-cancer Properties and Potency of Synthetic Indole-3-carbinol Derivatives

, 2019; 19(7): 540-554.

Mojgan Noroozi Karimabad, Mehdi Mahmoodi, Abdolah Jafarzadeh, Ali Darekordi, Mohamad Reza Hajizadeh and Gholamhossein Hassanshahi*


DOI: 10.2174/1389557518666181116120145





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