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Mini-Reviews in Medicinal Chemistry

Volume 19, 20 Issues, 2019
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

Ranking and Category

  • 27th of 61 in

    Chemistry, Medicinal

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Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

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Volume 19

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Number 10



Biography   Open Access



Review Article



Review Article



Review Article



Review Article



Research Article

Synthesis and Molecular Docking of New Thiophene Derivatives as Lactate Dehydrogenase-A Inhibitors

, 19(10): 833 - 841

Abd El-Galil E. Amr*, Mohamed F. El-Shehry, Alhussein A. Ibrahim, Hanaa M. Hosni, Mohamed A. Al-Omar and Hazem A. Ghabbour


DOI: 10.2174/1389557519666190212165302


Research Article

Ultrasound Assisted Synthesis of 3-(het)aryl Isocoumarin Derivatives and their in vitro Pharmacological Evaluation

, 19(10): 842 - 850

Gutta Lakshmi Prasanna, V.D. Nagendra Kumar Abbaraju, Yarlagadda Bharath, Mandava V. Basaveswara Rao* and Manojit Pal*


DOI: 10.2174/1389557519666190130163708


Research Article



Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 13


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 12


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 19 (2019) - Number 11


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



Recent Advances Towards Treatment of HIV: Synthesis and SAR Studies


Neelima Shrivastava, Asif Husain, Mohammad Rashid*, Shahid Karim, Nimer Fehaid Alsabeelah and Nasir Ali Siddiqui


View Abstract View on PubMed



Recent Advances in Apoptosis: THE Role of Hydrazones


Pelin Çıkla-Süzgün and Ş. Güniz Küçükgüzel*


View Abstract View on PubMed


Malaria Hybrids: A Chronological Evolution


Akranth Marella*, Garima Verma, Md. Shaquiquzzaman, Md. Faraz Khan, Wasim Akhtar and Md. Mumtaz Alam*


View Abstract View on PubMed


Human Galectin-1 and Its Inhibitors: Privileged Target for Cancer and HIV


Narella Sridhar Goud, P. S. Lakshmi Soukya, Mahammad Ghouse, Daipule Komal, Ravi Alvala and Mallika Alvala*


View Abstract View on PubMed



Protective Role of Natural Products in Cisplatin-Induced Nephrotoxicity


Nurul Raudzah Adib Ridzuan, Norhashima Abd Rashid, Faizah Othman, Siti Balkis Budin, Farida Hussan and Seong Lin Teoh*


View Abstract View on PubMed


Synthesis of Novel Bis-pyrazole Derivatives as Antimicrobial Agents


Zeinab A. Muhammad, Fatimah Alshehrei, Mohie E. M. Zayed, Thoraya A. Farghaly* and Magda A. Abdallah


View Abstract View on PubMed


Abstracts Ahead of Print

Protective effects of phenylpropanoids and phenylpropanoid-rich essential oils on the cardiovascular system


Jorge Alves Silva, Mónica Zuzarte*, Carla Marques, Henrique Girão and Lígia Salgueiro


View Abstract


A review on anticancer potentials of benzothiazole derivatives


Nandini Pathak, Ekta Rathi, Nitesh Kumar*, Suvarna G. Kini and C. Mallikarjuna Rao


View Abstract




The roles of Flavonoles/Flavonoids in Neurodegeneration and Neuroinflammation


Zehra Calis, Rasim Mogulkoc* and Abdülkerim Kasim Baltaci


View Abstract



Synthesis of Azoloquinazolines and substituted benzothiazepine as antimicrobial agents


Asmaa F. Kassem, Fatimah Alshehrei, Eman M. H. Abbas and Thoraya A. Farghaly*


View Abstract


PPAR Ligands Containing Stilbene Scaffold


Marialuigia Fantacuzzi, Barbara De Filippis*, Rosa Amoroso and Letizia Giampietro


View Abstract


Spinacia oleracea Linn Considered as one of the Most Perfect Foods: an Pharmacological and Phytochemical Review


Rosa Martha Perez Gutierrez*, Elisa Gutierrez Velazquez and Silvia Patricia Paredes Carrera


View Abstract



Published Contents

Editor's Choice

Non-adenosine Nucleoside Inosine, Guanosine and Uridine as Promising Antiepileptic Drugs: a Summary of Current Literature

, 2014; 14(13): 1033 - 1042

Zsolt Kovacs, Katalin A. Kekesi, Gabor Juhasz, Janos Barna, Laszlo Heja, Renata Lakatos and Arpad Dobolyi


DOI: 10.2174/1389557514666141107120226



Combined Cancer Therapy with Non-Conventional Drugs: All Roads Lead to AMPK

, 2014; 14(8): 642 - 654

Suning Chen, Xingmei Zhu, Xiaofeng Lai, Tian Xiao, Aidong Wen and Jian Zhang


DOI: 10.2174/1389557514666140820104444



Antiaging Therapy: A Novel Target for Antilipolytic Drugs

, 2014; 14(7): 551 - 556

Gabriella Cavallini, Alessio Donati and Ettore Bergamini


DOI: 10.2174/1389557514666140622205540



Application of BRET for Studying G Protein-Coupled Receptors

, 2014; 14(5): 411 - 425

Agnieszka A. Kaczor, Magdalena Makarska-Bialokoz, Jana Selent, Rocio A. de la Fuente, Maria Marti-Solano and Marian Castro


DOI: 10.2174/1389557514666140428113708



Open Access Articles

Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng





G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek





Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic








Most Cited Articles

Review Article

An overview on application of natural substances incorporated with electrospun nanofibrous scaffolds to development of innovative wound dressings

, 2018; 18(5): 414-427.

Younes Pilehvar-Soltanahmadi, Mehdi Dadashpour, Abbas Mohajeri, Amir Fattahi, Roghayeh Sheervalilou and Nosratollah Zarghami*


DOI: 10.2174/1389557517666170308112147


Review Article

Advance in anti-tumor mechanisms of shikonin, alkannin and their derivatives

, 2018; 18(2): 164-172.

Xu Zhang, Jia-Hua Cui, Qing-Qing Meng, Shao-Shun Li, Wen Zhou* and Sui Xiao*


DOI: 10.2174/1389557517666170228114809




Review Article

Synthetic and natural lipase inhibitors

, 2018; 18(8): 672-683.

Ewa Bialecka-Florjanczyk*, Agata Urszula Fabiszewska, Jolanta Krzyczkowska and Alina Kurylowicz


DOI: 10.2174/1389557516666160630123356



Review Article

Quinoxalinone as a privileged platform in drug development

, 2018; 18(5): 392-413.

Leilei Shi, Wei Hu, Jifeng Wu, Huaiyu Zhou, Hua Zhou and Xun Li*


DOI: 10.2174/1389557517666171101111134


Review Article

Recent advances on 3-hydroxyflavone derivatives: Structures and properties

, 2018; 18(2): 98-103.

Burcu Butun, Gulacti Topcu and Turan Ozturk*


DOI: 10.2174/1389557517666170425102827


Review Article

Berberine derivatives with different pharmacological activities via structural modifications

, 2018; 18(17): 1424-1441.

Daipeng Xiao, Zhenbao Liu, Shanshan Zhang, Mi Zhou, Fen He, Ming Zou, Junying Peng, Xiong Xie, Yanfei Liu* and Dongming Peng*


DOI: 10.2174/1389557517666170321103139


Review Article

Rubiscolins - Highly potent peptides derived from plant proteins

, 2018; 18(2): 104-112.

Renata Perlikowska* and Anna Janecka


DOI: 10.2174/1389557517666170426160703



Review Article

The synthetic and biological attributes of pyrazole derivatives: A review

, 2018; 18(11): 918-947.

Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh


DOI: 10.2174/1389557517666170927160919


Review Article

CORAL: Monte carlo method to predict endpoints for medical chemistry

, 1 January 2018; 18(5): 382-391.

Alla P. Toropova* and Andrey A. Toropov*


DOI: 10.2174/1389557517666170927154931



Review Article

Ellagitannins: Bioavailability, purification and biotechnological degradation

, 2018; 18(15): 1244-1252.

Pedro Aguilar-Zarate, Jorge E. Wong-Paz, Juan J. Buenrostro-Figueroa, Juan A. Ascacio, Juan C. Contreras-Esquivel and Cristóbal N. Aguilar*


DOI: 10.2174/1389557517666170208144742



Most Accessed Articles

Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

, 2016; 16(2): 120-162.

Ajmer Singh Grewal, Shashikant Bhardwaj, Deepti Pandita, Viney Lather and Bhupinder Singh Sekhon


DOI: 10.2174/1389557515666150909143737




Molecular Targets, Anti-cancer Properties and Potency of Synthetic Indole-3-carbinol Derivatives

, 2019; 19(7): 540-554.

Mojgan Noroozi Karimabad, Mehdi Mahmoodi, Abdolah Jafarzadeh, Ali Darekordi, Mohamad Reza Hajizadeh and Gholamhossein Hassanshahi*


DOI: 10.2174/1389557518666181116120145



A Review Exploring Therapeutic Worth of 1,3,4-Oxadiazole Tailored Compounds

, 2019; 19(6): 477-509.

Garima Verma, Mohemmed F. Khan, Wasim Akhtar, Mohammad Mumtaz Alam, Mymoona Akhter and Mohammad Shaquiquzzaman*


DOI: 10.2174/1389557518666181015152433


Aqueous Drug Solubility: What Do We Measure, Calculate and QSPR Predict?

, 2019; 19(5): 362-372.

Oleg A. Raevsky*, Veniamin Y. Grigorev, Daniel E. Polianczyk, Olga E. Raevskaja and John C. Dearden


DOI: 10.2174/1389557518666180727164417



The Relationship between Pharmacological Properties and Structure- Activity of Chrysin Derivatives

, 2019; 19(7): 555-568.

Yang Li, Yan-peng Li, Jun He*, Ding Liu, Qi-zhi Zhang, Kang Li, Xing Zheng, Guo-Tao Tang, Yu Guo and Yunmei Liu*


DOI: 10.2174/1389557518666180424094821



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