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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 19, 8 Issues, 2019
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Ranking and Category

  • 134th of 145 in

    Endocrinology & Metabolism

  • 148th of 158 in

    Immunology

  • 237th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

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Volume 19

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Number 6



Editorial   Open Access



Review Article



Review Article

Diabetes-induced Proteome Changes Throughout Development

, 19(6): 732 - 743

Dina Johar*, Sara M. Ahmed, Samer El. Hayek, Nader Al-Dewik, Eshak I. Bahbah, Nabil H. Omar, Mahmoud Mustafa, Doaa O. Salman, Asmaa Fahmey, Mohamed Mottawea, Rasha A.M. Azouz and Larry Bernstein


DOI: 10.2174/1871530319666190305153810


Review Article



Review Article

Lead Optimization Resources in Drug Discovery for Diabetes

, 19(6): 754 - 774

Pragya Tiwari*, Ashish Katyal, Mohd F. Khan, Ghulam Md. Ashraf* and Khurshid Ahmad*


DOI: 10.2174/1871530319666190304121826


Review Article



General Review Article

The Pleiotropic Effects of Statins in Endocrine Disorders

, 19(6): 787 - 793

Javier A. De La Cruz , Christos G. Mihos , Sofia A. Horvath and Orlando Santana *


DOI: 10.2174/1871530319666190329115003


General Review Article



Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 19 (2019) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

LncRNA, Important Player in Bone Development and Disease


Dijie Li, Chaofei Yang, Chong Yin, Fan Zhao, Zhihao Chen, Ye Tian, Kai Dang, Shanfeng Jiang, Wenjuan Zhang, Ge Zhang and Airong Qian*


DOI: 10.2174/1871530319666190904161707
View Abstract


Prolonged Adrenal Insufficiency After the Discontinuation of Mitotane Therapy


Leonardo Muratori , Anna Pia, Giuseppe Reimondo, Chiara Pisano, Anna La Salvia, Soraya Puglisi, Giorgio Vittorio Scagliotti and Paola Sperone


DOI: 10.2174/1871530319666190809144620
View Abstract View on PubMed


Blockade of Renin Angiotensin System Ameliorates the Cardiac Arrythmias and Sympathetic Neural Remodeling in Hearts of Type 2 DM Rat Model


Yomna M. Yehya, Abdelaziz M. Hussein*, Khaled Ezam, Elsayed A. Eid, Eman M. Ibraheim, Mohamed A.F.E. Sarhan, Aya Elsayed and Mohamed E. Sarhan


DOI: 10.2174/1871530319666190809150921
View Abstract View on PubMed







Anti-cancerous Effect of Rutin Against HPV-C33A Cervical Cancer Cells via G0/G1 Cell Cycle Arrest and Apoptotic Induction


Fahad Khan, Pratibha Pandey*, Tarun Kumar Upadhyay, Asif Jafri, Niraj Kumar Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257
View Abstract View on PubMed



Abstracts Ahead of Print

Diagnostic Approach to The Patients with Suspected Primary Immunodeficiency


Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi*, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani and Asghar Aghamohammadi


DOI: 10.2174/1871530319666190828125316
View Abstract


Can Anti-Thyroid Antibodies Influence the Outcome of Primary Chronic Immune Thrombocytopenia in Children?


Paola Giordano, Maurizio Delvecchio, Giuseppe Lassandro, Federica Valente, Valentina Palladino, Mariangela Chiarito, Malgorzata Wasniewska and Maria Felicia Faienza*


DOI: 10.2174/1871530319666190905161347
View Abstract



Published Contents

Editor's Choice

The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms

, 2019; 19(6): 874 - 884

Mina Abdolahi, Arash Jafarieh, Payam Sarraf, Mohsen Sedighiyan, Abolghasem Yousefi, Abbas Tafakhori, Hamed Abdollahi, Farahnaz Salehinia and Mahmoud Djalali*


DOI: 10.2174/1871530319666190212170140





Potent Inhibitory Effects of Quercetin on Inflammatory Responses of Collagen-Induced Arthritis in Mice

, 2019; 19(3): 308 - 315

Kiichiro Kawaguchi, Masahiro Kaneko*, Ryo Miyake, Hiroaki Takimoto and Yoshio Kumazawa


DOI: 10.2174/1871530319666190206225034




Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos


DOI: 10.2174/1871530318666180801125258




Vitamin D status in coronary artery disease: association with IL-35 and TGF-β1 and disease severity

, 2018; 18(5): 522 - 529

Fereshteh Rasa, Nadereh Naderi, Ebrahim Eftekhar, Elahe Mansoori and Mahsa Rahimzadeh*


DOI: 10.2174/1871530318666180426101756




Relationship between Proinflammatory Cytokines/Chemokines and Adipokines in Serum of Young Adults with Obesity

, 2018; 18(3): 260 - 267

Maraisa D. Borges, Eduardo L. Franca, Mahmi Fujimori, Silvia M.C. Silva, Patricia G.F. de Marchi, Alessandra L. Deluque, Adenilda C. Honorio-Franca* and Luiz C. de Abreu


DOI: 10.2174/1871530318666180131094733



Open Access Articles

B Lymphocytes Are Predictors of Insulin Resistance in Women with Gestational Diabetes Mellitus

, 2019; 19(3): 358 - 366

Yan Zhuang, Jin Zhang, Yiwei Li, Hongqin Gu, Jinyan Zhao, Ya Sun, Rencheng Wang, Chunyan Zhang, Wen Chen, Jianrong Weng, Lan Qi, Huifang Lu, Jiarong Zhang, Qin Liu, Yinyan He* and Xianming Xu




The Epithelial Barrier Model Shows That the Properties of VSL#3 Depend from Where it is Manufactured

, 2019; 19(2): 199 - 206

Paola Palumbo*, Francesca Lombardi, Maria Grazia Cifone and Benedetta Cinque





Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos




Pioglitazone Therapy and Fractures: Systematic Review and Meta- Analysis

, 2018; 18(5): 502 - 507

Velichka Pavlova*, Elena Filipova, Katya Uzunova, Krassimir Kalinov and Toni Vekov




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Assessment of Response to Treatment and Follow-Up in Gastroenteropancreatic Neuroendocrine Neoplasms

, 2018; 18(5): 419 - 449

Franco Grimaldi*, Nicola Fazio*, Roberto Attanasio, Andrea Frasoldati, Enrico Papini, Nadia Cremonini, Maria V. Davi, Luigi Funicelli, Sara Massironi, Francesca Spada, Vincenzo Toscano, Annibale Versari, Michele Zini, Massimo Falconi and Kjell Oberg




Shift from Levothyroxine Tablets to Liquid Formulation at Breakfast Improves Quality of Life of Hypothyroid Patients

, 2018; 18(3): 235 - 240

Rinaldo Guglielmi, Franco Grimaldi, Roberto Negro, Andrea Frasoldati, Irene Misischi, Filomena Graziano, Claudia Cipri, Edoardo Guastamacchia, Vincenzo Triggiani* and Enrico Papini




GH Supplementation Effects on Cardiovascular Risk in GH Deficient Adult Patients: A Systematic Review and Meta-analysis

, 2017; 17(4): 285 - 296

Vito A. Giagulli*, Marco Castellana, Raffaella Perrone, Edoardo Guastamacchia, Massimo Iacoviello and Vincenzo Triggiani




Cerebral Hypoperfusion in Hereditary Coproporphyria (HCP): A Single Photon Emission Computed Tomography (SPECT) Study

, 2016; 16(1): 39 - 46

Guido Valle, Claudio Carmine Guida, Michelangelo Nasuto, Manuela Totaro, Filippo Aucella, Vincenzo Frusciante, Lazzaro Di Mauro, Adele Potenza, Maria Savino, Mario Stanislao, Teresa Popolizio, Giuseppe Guglielmi, Vito Angelo Giagulli, Edoardo Guastamacchia and Vincenzo Triggiani





Thalidomide Controls Adipose Tissue Inflammation Associated with High- Fat Diet-Induced Obesity in Mice

, 2015; 15(2): 151 - 158

Patricia Z Nakamitsu, Cecilia M. Compri, Livia de Fraia Pinto, Erica M.F. Gotardo, Caroline C. de Oliveira, Marcelo L. Ribeiro, Jose Pedrazzoli and Alessandra Gambero




Vitamins and Type 2 Diabetes Mellitus

, 2015; 15(1): 54 - 63

Roxana Valdes-Ramos, Guadarrama-Lopez A. Laura, Martinez-Carrillo B. Elina and Benitez-Arciniega A. Donaji




Neutrophil Derived Microvesicles: Emerging Role of a Key Mediator to the Immune Response

, 2014; 14(3): 210 - 217

Bobby L. Johnson, III, Josh W. Kuethe and Charles C. Caldwell




Recent Advances in the Understanding of Sepsis-Induced Alterations in the Neuroendocrine System

, 2013; 13(4): 335 - 347

Fazal Wahab, Bibi Atika, Gabriela R. Oliveira-Pelegrin and Maria J. A. Rocha






Most Cited Articles


Research Article

Olive leaf extracts act as modulators of the human immune response

, 2018; 18(1): 85-93.

Thea Magrone*, Anna Spagnoletta, Rosaria Salvatore, Manrico Magrone, Francesco Dentamaro, Matteo A. Russo, Graziana Difonzo, Carmine Summo, Francesco Caponio and Emilio Jirillo


DOI: 10.2174/1871530317666171116110537



Review Article

Effects of olive oil on TNF-α and IL-6 in humans: Implication in obesity and frailty

, 1 January 2018; 18(1): 63-74.

Nagendra S. Yarla, Angela Polito and Ilaria Peluso*


DOI: 10.2174/1871530317666171120150329


Review Article

The protective effects of extra virgin olive oil on immune-mediated inflammatory responses

, 1 January 2018; 18(1): 23-35.

Rosa Casas, Ramon Estruch and Emilio Sacanella*


DOI: 10.2174/1871530317666171114115632


Review Article

Olive Oil-related anti-inflammatory effects on atherosclerosis: Potential clinical implications

, 1 January 2018; 18(1): 51-62.

Tanakal Wongwarawipat, Nikolaos Papageorgiou*, Dimitrios Bertsias, Gerasimos Siasos and Dimitris Tousoulis


DOI: 10.2174/1871530317666171116103618


Research Article

Relationship between proinflammatory cytokines/chemokines and adipokines in serum of young adults with obesity

, 1 May 2018; 18(3): 260-267.

Maraisa D. Borges, Eduardo L. Franca, Mahmi Fujimori, Silvia M.C. Silva, Patricia G.F. de Marchi, Alessandra L. Deluque, Adenilda C. Honorio-Franca* and Luiz C. de Abreu


DOI: 10.2174/1871530318666180131094733



Review Article

Roles of glutamate and glutamine transport in ammonia neurotoxicity: State of the art and question marks

, 2018; 18(4): 306-315.

Katarzyna Dabrowska*, Katarzyna Skowronska, Mariusz Popek, Marta Obara-Michlewska, Jan Albrecht and Magdalena Zielinska*


DOI: 10.2174/1871520618666171219124427


Review Article

The role of neurohypophyseal hormones vasopressin and oxytocin in neuropsychiatric disorders

, 2018; 18(4): 341-347.

Michele Iovino, Tullio Messana, Giovanni De Pergola, Emanuela Iovino, Franca Dicuonzo, Edoardo Guastamacchia, Vito Angelo Giagulli and Vincenzo Triggiani*


DOI: 10.2174/1871530318666180220104900


Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini*, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352


Review Article

Recent advances in endocrine, metabolic and immune disorders: Mesenchymal stem cells (MSCs) and engineered scaffolds

, 2018; 18(5): 466-469.

Stefania Cantore, Vito Crincoli, Antonio Boccaccio, Antonio E. Uva, Michele Fiorentino, Giuseppe Monno, Patrizio Bollero, Chiara Derla, Francesca Fabiano, Andrea Ballini and Luigi Santacroce*


DOI: 10.2174/1871530318666180423102905


Review Article

Interplay of gut microbiota, probiotics in obesity: A review

, 1 May 2018; 18(3): 212-220.

Ramesh Pothuraju* and Raj K. Sharma


DOI: 10.2174/1871530318666180131092203


Review Article

A clinical update and global economic burden of rheumatoid arthritis

, 1 March 2018; 18(2): 98-109.

Syed Ali Fazal, Mohammad Khan, Shamima E. Nishi, Fahmida Alam, Nowshin Zarin, Mohammad T. Bari and Ghulam Md. Ashraf*


DOI: 10.2174/1871530317666171114122417


Review Article

Effect of extra virgin olive oil and table olives on the immuneInflammatory responses: Potential clinical applications

, 2018; 18(1): 14-22.

Caterina M. Gambino , Giulia Accardi , Anna Aiello, Giuseppina Candore, Giovanni Dara-Guccione , Mario Mirisola , Antonio Procopio, Giusi Taormina and Calogero Caruso *


DOI: 10.2174/1871530317666171114113822



Most Accessed Articles

Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences

, 2019; 19(3): 247-258.

Mahsa Hatami, Mina Abdolahi, Neda Soveyd, Mahmoud Djalali, Mansoureh Togha and Niyaz Mohammadzadeh Honarvar*


DOI: 10.2174/1871530319666181129103056


Targeting Wnt Signaling through Small molecules in Governing Stem Cell Fate and Diseases

, 2019; 19(3): 233-246.

Antara Banerjee*, Ganesan Jothimani, Suhanya Veronica Prasad, Francesco Marotta and Surajit Pathak


DOI: 10.2174/1871530319666190118103907




Focus on the Correlations between Alzheimer’s Disease and Type 2 Diabetes

, 2019; 19(5): 571-579.

Vincenzo Fiore*, Antonia De Rosa, Paolo Falasca, Massimo Marci, Edoardo Guastamacchia, Brunella Licchelli, Vito Angelo Giagulli, Giovanni De Pergola, Antonella Poggi and Vincenzo Triggiani*


DOI: 10.2174/1871530319666190311141855




Diabetes Association with Liver Diseases: An Overview for Clinicians

, 2019; 19(3): 274-280.

Abd Elkhalek Hamed, Nadia Elwan, Mervat Naguib, Reda Elwakil, Gamal Esmat, Mohamed El Kassas, Sherief Abd-Elsalam* and Shorouk Moussa


DOI: 10.2174/1871530318666181116111945


B Lymphocytes Are Predictors of Insulin Resistance in Women with Gestational Diabetes Mellitus

, 2019; 19(3): 358-366.

Yan Zhuang, Jin Zhang, Yiwei Li, Hongqin Gu, Jinyan Zhao, Ya Sun, Rencheng Wang, Chunyan Zhang, Wen Chen, Jianrong Weng, Lan Qi, Huifang Lu, Jiarong Zhang, Qin Liu, Yinyan He* and Xianming Xu


DOI: 10.2174/1871530319666190101130300





Editor-in-Chief

Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
Italy

Biography View Full Editorial Board

Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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