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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 19, 8 Issues, 2019
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Ranking and Category

  • 134th of 145 in

    Endocrinology & Metabolism

  • 148th of 158 in

    Immunology

  • 237th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

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Volume 19

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Number 4



Editorial   Open Access



Review Article



Review Article

Multi-Target Drugs Against Metabolic Disorders

, 19(4): 402 - 418

Luciana Scotti*, Alex France Messias Monteiro, Jéssika de Oliveira Viana, Francisco Jaime Bezerra Mendonça Junior, Hamilton M. Ishiki, Ernestine Nkwengoua Tchouboun, Rodrigo Santos and Marcus Tullius Scotti


DOI: 10.2174/1871530319666181217123357


Research Article



Research Article

Prevalence of Extended-Spectrum β-Lactamases in Multi-drug Resistant Pseudomonas aeruginosa from Diabetic Foot Patients

, 19(4): 443 - 448

Faaiz ul Hassan, Muhammad Suhaib Qudus, Sheikh Arslan Sehgal, Jawad Ahmed, Momin Khan, Khayam ul Haq, Shahina Mumtaz, Muhammad Arshad and Sami Siraj*


DOI: 10.2174/1871530319666181128095753


Research Article



General Review Article

Metabolic Association between Leptin and the Corticotropin Releasing Hormone

, 19(4): 458 - 466

Sofia Gioldasi, Alexia Karvela, Andrea Paola Rojas-Gil, Maria Rodi, Anne-Lise de Lastic, Iason Thomas, Bessie E. Spiliotis and Athanasia Mouzaki*


DOI: 10.2174/1871530319666190206165626


General Review Article



Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 19 (2019) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Imbalance of Steroid Hormones in Hamsters Infected with Schistosoma mansoni


Oliveira K.C., Cardoso R., Dos Santos A.C., Fernandes R and Botelho M.C.*


View Abstract View on PubMed




Women in LOVe: Lacto-Ovo-Vegetarian Diet Rich in Omega-3 Improves Vasomotor Symptoms in Postmenopausal Women. An Exploratory Randomized Controlled Trial


Ornella Rotolo , Iris Zinzi , Nicola Veronese , Anna Maria Cisternino , Rosa Reddavide , Rosa Inguaggiato , Gioacchino Leandro , Maria Notarnicola , Valeria Tutino , Valentina De Nunzio , Giampiero De Leonardis , Vito Guerra , Rossella Donghia , Fabio Fucilli , Raffaella Licinio , Anna Mastrosimini , Costanza Mammone Rinaldi, Tiziana Daddabbo, Nicola Giampaolo , Palma Aurelia Iacovazzi, Sara Giannico and Maria Gabriella Caruso


View Abstract View on PubMed


Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in Kurdistan Province


Wesam Kooti*, Mohammad Abdi, Yashpal S. Malik, Bijan Nouri, Ali Jalili, Mohammad Ali Rezaee, Moahmad Reza Rahmani and Rasoul Nasiri Kalmarzi


View Abstract View on PubMed


The Prevalence of Allergic Rhinitis among Iranian Children: A Systematic Review and Meta-Analysis


Rasoul Nasiri Kalmarzi, Pedram Ataee, Asadolllah Fathollahpour, Masoud Behzadifar, Maryam Moradi, Faezeh Sharifian, Navid Kalani and Wesam Kooti*


View Abstract View on PubMed



Diabetes-Induced Proteome Changes Throughout Development


Dina Johar*, Sara M. Ahmed, Samer El Hayek, Nader Al-Dewik, Eshak I. Bahbah, Nabil H. Omar, Mahmoud Mustafa, Doaa O. Salman, Asmaa Fahmey, Mohamed Mottawea, Rasha A. M. Azouz and Larry Bernstein


View Abstract View on PubMed



Metformin: Up to Date


Sciannimanico Silvia, Grimaldi Franco, Vescini Fabio, Giovanni De Pergola , Massimo Iacoviello, Brunella Licchelli , Edoardo Guastamacchia , VitoAngelo Giagulli and Vincenzo Triggiani *


View Abstract


Abstracts Ahead of Print

Future Perspective of Diabetic Animal Models


Shashank Pandey and Magdalena Chottova Dvorakova*


View Abstract



A Historical Review of Persian Medicine Studies into Saliva Manifestations for Potential Applications for Diagnosis and Management of Metabolic Syndrome


Fatemeh Hakimi, Rasool Choopani, Majid Asghari, Hasan Namdar, Elham Parsa, Parisa Jafari and Mina Movahhed*


View Abstract




Atorvastatin Inhibited ROS Generation And Increased IL-1β And IL-6 Release By Mononuclear Cells From Diabetic Patients


Paula Martins Ferreira dos Anjos, Caroline Maria Maria Oliveira Volpe, Thaís Cristina Miranda and José Augusto Nogueira-Machado*


View Abstract


Metabolic imbalance and vitamin D deficiency in type 1 diabetes in the Algerian population


E Mihoubi, R Raache*, Amroun H, M Azzouz, Galleze A, N Zaabat, A Aissou, Ferhat A, Guettaf H, Boutemeur A, Aoudia Z, Boudiba, Touil Boukouffa C, M C Abbadi and Attal N


View Abstract


Role of Both Protein C and Antithrombin III as Predictors of stage of liver disease in Chronic Viral Hepatitis B or C Infected patients


Amany Mohamed Abo-Elenein, Maaly Mohamed Mabrouk, Sabry Abou-Saif, Ola Mohamed Saeed, Samy Khodeir, Mahmoud Elkadeem, Heba Elashry, Tamer Haydara, Mariam Salah Zaghloul, Waseem M. Seleem, Samah A Elshweikh and Sherief Abd-Elsalam*


View Abstract


The association between dyslipidemia and preterm birth: A prospective study in the North of Iran


Seyedeh Hajar Sharami, Mahboobeh Gholipour, Forozan Milani, Ehsan Kazemnejad, Seyedeh Fatemeh Dalil Heirati and Zahra Abbasi Ranjbar*


View Abstract



Published Contents

Editor's Choice


Potent Inhibitory Effects of Quercetin on Inflammatory Responses of Collagen-Induced Arthritis in Mice

, 2019; 19(3): 308 - 315

Kiichiro Kawaguchi, Masahiro Kaneko*, Ryo Miyake, Hiroaki Takimoto and Yoshio Kumazawa


DOI: 10.2174/1871530319666190206225034




Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos


DOI: 10.2174/1871530318666180801125258




Vitamin D status in coronary artery disease: association with IL-35 and TGF-β1 and disease severity

, 2018; 18(5): 522 - 529

Fereshteh Rasa, Nadereh Naderi, Ebrahim Eftekhar, Elahe Mansoori and Mahsa Rahimzadeh*


DOI: 10.2174/1871530318666180426101756




Relationship between Proinflammatory Cytokines/Chemokines and Adipokines in Serum of Young Adults with Obesity

, 2018; 18(3): 260 - 267

Maraisa D. Borges, Eduardo L. Franca, Mahmi Fujimori, Silvia M.C. Silva, Patricia G.F. de Marchi, Alessandra L. Deluque, Adenilda C. Honorio-Franca* and Luiz C. de Abreu


DOI: 10.2174/1871530318666180131094733



Mannose-Binding Lectin Protein Deficiency Among Patients with Primary Immunodeficiency Disease Receiving IVIG Therapy

, 2018; 18(2): 175 - 183

Gholamreza Azizi, Fatemeh Kiaee, Somaye Yaslianifard, Hosein Rafiemanesh, Sara Mohammadikhajehdehi, Hamed Mohammadi, Seyed Sakineh Miresmaeeli, Leila H. Pour, Sina Abdolrahim Poor Heravi, Laleh Sharifi, Reza Yazdani, Hassan Abolhassani and Asghar Aghamohammadi*


DOI: 10.2174/1871530317666171108111749




Open Access Articles

B Lymphocytes Are Predictors of Insulin Resistance in Women with Gestational Diabetes Mellitus

, 2019; 19(3): 358 - 366

Yan Zhuang, Jin Zhang, Yiwei Li, Hongqin Gu, Jinyan Zhao, Ya Sun, Rencheng Wang, Chunyan Zhang, Wen Chen, Jianrong Weng, Lan Qi, Huifang Lu, Jiarong Zhang, Qin Liu, Yinyan He* and Xianming Xu




The Epithelial Barrier Model Shows That the Properties of VSL#3 Depend from Where it is Manufactured

, 2019; 19(2): 199 - 206

Paola Palumbo*, Francesca Lombardi, Maria Grazia Cifone and Benedetta Cinque





Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos




Pioglitazone Therapy and Fractures: Systematic Review and Meta- Analysis

, 2018; 18(5): 502 - 507

Velichka Pavlova*, Elena Filipova, Katya Uzunova, Krassimir Kalinov and Toni Vekov




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Assessment of Response to Treatment and Follow-Up in Gastroenteropancreatic Neuroendocrine Neoplasms

, 2018; 18(5): 419 - 449

Franco Grimaldi*, Nicola Fazio*, Roberto Attanasio, Andrea Frasoldati, Enrico Papini, Nadia Cremonini, Maria V. Davi, Luigi Funicelli, Sara Massironi, Francesca Spada, Vincenzo Toscano, Annibale Versari, Michele Zini, Massimo Falconi and Kjell Oberg




Shift from Levothyroxine Tablets to Liquid Formulation at Breakfast Improves Quality of Life of Hypothyroid Patients

, 2018; 18(3): 235 - 240

Rinaldo Guglielmi, Franco Grimaldi, Roberto Negro, Andrea Frasoldati, Irene Misischi, Filomena Graziano, Claudia Cipri, Edoardo Guastamacchia, Vincenzo Triggiani* and Enrico Papini




GH Supplementation Effects on Cardiovascular Risk in GH Deficient Adult Patients: A Systematic Review and Meta-analysis

, 2017; 17(4): 285 - 296

Vito A. Giagulli*, Marco Castellana, Raffaella Perrone, Edoardo Guastamacchia, Massimo Iacoviello and Vincenzo Triggiani




Cerebral Hypoperfusion in Hereditary Coproporphyria (HCP): A Single Photon Emission Computed Tomography (SPECT) Study

, 2016; 16(1): 39 - 46

Guido Valle, Claudio Carmine Guida, Michelangelo Nasuto, Manuela Totaro, Filippo Aucella, Vincenzo Frusciante, Lazzaro Di Mauro, Adele Potenza, Maria Savino, Mario Stanislao, Teresa Popolizio, Giuseppe Guglielmi, Vito Angelo Giagulli, Edoardo Guastamacchia and Vincenzo Triggiani





Thalidomide Controls Adipose Tissue Inflammation Associated with High- Fat Diet-Induced Obesity in Mice

, 2015; 15(2): 151 - 158

Patricia Z Nakamitsu, Cecilia M. Compri, Livia de Fraia Pinto, Erica M.F. Gotardo, Caroline C. de Oliveira, Marcelo L. Ribeiro, Jose Pedrazzoli and Alessandra Gambero




Vitamins and Type 2 Diabetes Mellitus

, 2015; 15(1): 54 - 63

Roxana Valdes-Ramos, Guadarrama-Lopez A. Laura, Martinez-Carrillo B. Elina and Benitez-Arciniega A. Donaji




Neutrophil Derived Microvesicles: Emerging Role of a Key Mediator to the Immune Response

, 2014; 14(3): 210 - 217

Bobby L. Johnson, III, Josh W. Kuethe and Charles C. Caldwell




Recent Advances in the Understanding of Sepsis-Induced Alterations in the Neuroendocrine System

, 2013; 13(4): 335 - 347

Fazal Wahab, Bibi Atika, Gabriela R. Oliveira-Pelegrin and Maria J. A. Rocha






Most Cited Articles


Review Article

The protective effects of extra virgin olive oil on immune-mediated inflammatory responses

, 1 January 2018; 18(1): 23-35.

Rosa Casas, Ramon Estruch and Emilio Sacanella*


DOI: 10.2174/1871530317666171114115632


Review Article

Effects of olive oil on TNF-α and IL-6 in humans: Implication in obesity and frailty

, 1 January 2018; 18(1): 63-74.

Nagendra S. Yarla, Angela Polito and Ilaria Peluso*


DOI: 10.2174/1871530317666171120150329



Review Article

Olive Oil-related anti-inflammatory effects on atherosclerosis: Potential clinical implications

, 1 January 2018; 18(1): 51-62.

Tanakal Wongwarawipat, Nikolaos Papageorgiou*, Dimitrios Bertsias, Gerasimos Siasos and Dimitris Tousoulis


DOI: 10.2174/1871530317666171116103618


Review Article

Roles of glutamate and glutamine transport in ammonia neurotoxicity: State of the art and question marks

, 2018; 18(4): 306-315.

Katarzyna Dabrowska*, Katarzyna Skowronska, Mariusz Popek, Marta Obara-Michlewska, Jan Albrecht and Magdalena Zielinska*


DOI: 10.2174/1871520618666171219124427


Research Article

Olive leaf extracts act as modulators of the human immune response

, 2018; 18(1): 85-93.

Thea Magrone*, Anna Spagnoletta, Rosaria Salvatore, Manrico Magrone, Francesco Dentamaro, Matteo A. Russo, Graziana Difonzo, Carmine Summo, Francesco Caponio and Emilio Jirillo


DOI: 10.2174/1871530317666171116110537


Research Article

Relationship between proinflammatory cytokines/chemokines and adipokines in serum of young adults with obesity

, 1 May 2018; 18(3): 260-267.

Maraisa D. Borges, Eduardo L. Franca, Mahmi Fujimori, Silvia M.C. Silva, Patricia G.F. de Marchi, Alessandra L. Deluque, Adenilda C. Honorio-Franca* and Luiz C. de Abreu


DOI: 10.2174/1871530318666180131094733


Review Article

Recent advances in endocrine, metabolic and immune disorders: Mesenchymal stem cells (MSCs) and engineered scaffolds

, 2018; 18(5): 466-469.

Stefania Cantore, Vito Crincoli, Antonio Boccaccio, Antonio E. Uva, Michele Fiorentino, Giuseppe Monno, Patrizio Bollero, Chiara Derla, Francesca Fabiano, Andrea Ballini and Luigi Santacroce*


DOI: 10.2174/1871530318666180423102905


Review Article

Interplay of gut microbiota, probiotics in obesity: A review

, 1 May 2018; 18(3): 212-220.

Ramesh Pothuraju* and Raj K. Sharma


DOI: 10.2174/1871530318666180131092203


Review Article

The role of neurohypophyseal hormones vasopressin and oxytocin in neuropsychiatric disorders

, 2018; 18(4): 341-347.

Michele Iovino, Tullio Messana, Giovanni De Pergola, Emanuela Iovino, Franca Dicuonzo, Edoardo Guastamacchia, Vito Angelo Giagulli and Vincenzo Triggiani*


DOI: 10.2174/1871530318666180220104900



Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini*, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352


Review Article

A clinical update and global economic burden of rheumatoid arthritis

, 1 March 2018; 18(2): 98-109.

Syed Ali Fazal, Mohammad Khan, Shamima E. Nishi, Fahmida Alam, Nowshin Zarin, Mohammad T. Bari and Ghulam Md. Ashraf*


DOI: 10.2174/1871530317666171114122417


Research Article

Metabolic syndrome and cardiovascular risk in people treated with long-acting injectable antipsychotics

, 2018; 18(4): 379-387.

Vanessa Sanchez-Martinez*, Dolores Romero-Rubio, Maria Jose Abad-Perez, Maria Amparo Descalzo-Cabades, Sofia Alonso-Gutierrez, Jose Salazar-Fraile, Vicente Montagud and Lorenzo Facila


DOI: 10.2174/1871530317666171120151201



Most Accessed Articles


Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences

, 2019; 19(3): 247-258.

Mahsa Hatami, Mina Abdolahi, Neda Soveyd, Mahmoud Djalali, Mansoureh Togha and Niyaz Mohammadzadeh Honarvar*


DOI: 10.2174/1871530319666181129103056








Neuropsychiatric Aspects in Men with Klinefelter Syndrome

, 2019; 19(2): 109-115.

Vito Angelo Giagulli*, Beatrice Campone, Marco Castellana, Ciro Salzano, Alessandra Daphne Fisher, Cristina de Angelis, Rosario Pivonello, Annamaria Colao, Daniela Pasquali, Mario Maggi, Vincenzo Triggiani and On behalf of the Klinefelter ItaliaN Group (KING)


DOI: 10.2174/1871530318666180703160250


Targeting Wnt Signaling through Small molecules in Governing Stem Cell Fate and Diseases

, 2019; 19(3): 233-246.

Antara Banerjee*, Ganesan Jothimani, Suhanya Veronica Prasad, Francesco Marotta and Surajit Pathak


DOI: 10.2174/1871530319666190118103907




Editor-in-Chief

Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
Italy

Biography View Full Editorial Board

Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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