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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 19, 8 Issues, 2019
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

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Volume 19

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Number 3



Review Article

Targeting Wnt Signaling through Small molecules in Governing Stem Cell Fate and Diseases

, 19(3): 233 - 246

Antara Banerjee*, Ganesan Jothimani, Suhanya Veronica Prasad, Francesco Marotta and Surajit Pathak


DOI: 10.2174/1871530319666190118103907


Review Article

Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences

, 19(3): 247 - 258

Mahsa Hatami, Mina Abdolahi, Neda Soveyd, Mahmoud Djalali, Mansoureh Togha and Niyaz Mohammadzadeh Honarvar*


DOI: 10.2174/1871530319666181129103056


Review Article



Review Article

Diabetes Association with Liver Diseases: An Overview for Clinicians

, 19(3): 274 - 280

Abd Elkhalek Hamed, Nadia Elwan, Mervat Naguib, Reda Elwakil, Gamal Esmat, Mohamed El Kassas, Sherief Abd-Elsalam* and Shorouk Moussa


DOI: 10.2174/1871530318666181116111945


Review Article



Research Article



Research Article



Research Article



Articles Ahead of Print

The Pleiotropic Effects of Statins in Endocrine Disorders


Javier A. De La Cruz , Christos G. Mihos , Sofia A. Horvath and Orlando Santana *


View Abstract View on PubMed


Higher Levels of Serum TLR2 and TLR4 in Patients with Hashimoto's Thyroiditis


Tugba Aktaş, Sevim Karakas Celik*, Gunes Cakmak Genc, Dilek Arpaci, Murat Can and Ahmet Dursun


View Abstract View on PubMed


Diabetes-Induced Proteome Changes Throughout Development


Dina Johar*, Sara M. Ahmed, Samer El Hayek, Nader Al-Dewik, Eshak I. Bahbah, Nabil H. Omar, Mahmoud Mustafa, Doaa O. Salman, Asmaa Fahmey, Rasha A. M. Azouz and Larry Bernstein


View Abstract


A Brief History of Modern Endocrinology and Definitions of a True Hormone


Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi and Asghar Ghasemi*


View Abstract View on PubMed







Focus on the Correlations between Alzheimer’s Disease and Type 2 Diabetes


Vincenzo Fiore, Antonia De Rosa, Paolo Falasca, Massimo Marci, Edoardo Guastamacchia, Brunella Licchelli, Vito Angelo Giagulli, Giovanni De Pergola, Antonella Poggi and Vincenzo Triggiani*


View Abstract View on PubMed


Abstracts Ahead of Print



No correlation between blood benzene levels and luteinizing hormone plasma values in outdoor workers


Francesco Tomei, Maria Valeria Rosati, Giovanna Lo Russo, Lidia Ricci, Felice Marco Damato, Tiziana Caciari, Roberto Giubilati, Teodorico Casale, Bendetta Pimpinella, Stefania Marchione, Nadia Nardone, Natale Mario di Luca, Francesco Massoni, Vincenza Anzelmo, Roberto Massimi, Gianfranco Tomei, Pasquale Ricci, Carmina Sacco and Serafino Ricci*


View Abstract


Incidence of MicroR-4513C/T Gene Variability in Coronary Artery Disease- A case-Control Study


Rashid Mir*, Chandan k Jha, Imadeldin Elfaki, Jamsheed Javid, Suriya Rehman, Naina Khullar, Shaheena Banu and S. M. S. Chahal


View Abstract




Editor's Choice

Potent Inhibitory Effects of Quercetin on Inflammatory Responses of Collagen-Induced Arthritis in Mice

, 2019; 19(3): 308 - 315

Kiichiro Kawaguchi, Masahiro Kaneko*, Ryo Miyake, Hiroaki Takimoto and Yoshio Kumazawa


DOI: 10.2174/1871530319666190206225034




Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos


DOI: 10.2174/1871530318666180801125258




Vitamin D status in coronary artery disease: association with IL-35 and TGF-β1 and disease severity

, 2018; 18(5): 522 - 529

Fereshteh Rasa, Nadereh Naderi, Ebrahim Eftekhar, Elahe Mansoori and Mahsa Rahimzadeh*


DOI: 10.2174/1871530318666180426101756




Relationship between Proinflammatory Cytokines/Chemokines and Adipokines in Serum of Young Adults with Obesity

, 2018; 18(3): 260 - 267

Maraisa D. Borges, Eduardo L. Franca, Mahmi Fujimori, Silvia M.C. Silva, Patricia G.F. de Marchi, Alessandra L. Deluque, Adenilda C. Honorio-Franca* and Luiz C. de Abreu


DOI: 10.2174/1871530318666180131094733



Mannose-Binding Lectin Protein Deficiency Among Patients with Primary Immunodeficiency Disease Receiving IVIG Therapy

, 2018; 18(2): 175 - 183

Gholamreza Azizi, Fatemeh Kiaee, Somaye Yaslianifard, Hosein Rafiemanesh, Sara Mohammadikhajehdehi, Hamed Mohammadi, Seyed Sakineh Miresmaeeli, Leila H. Pour, Sina Abdolrahim Poor Heravi, Laleh Sharifi, Reza Yazdani, Hassan Abolhassani and Asghar Aghamohammadi*


DOI: 10.2174/1871530317666171108111749




Tissue Fatty Acid Profile is Differently Modulated from Olive Oil and Omega-3 Polyunsaturated Fatty Acids in ApcMin/+ Mice

, 2017; 17(4): 303 - 308

Valeria Tutino, Maria G. Caruso, Giampiero De Leonardis, Valentina De Nunzio and Maria Notarnicola*


DOI: 10.2174/1871530317666170911161623



Open Access Articles

B Lymphocytes Are Predictors of Insulin Resistance in Women with Gestational Diabetes Mellitus

, 2019; 19(3): 358 - 366

Yan Zhuang, Jin Zhang, Yiwei Li, Hongqin Gu, Jinyan Zhao, Ya Sun, Rencheng Wang, Chunyan Zhang, Wen Chen, Jianrong Weng, Lan Qi, Huifang Lu, Jiarong Zhang, Qin Liu, Yinyan He* and Xianming Xu




The Epithelial Barrier Model Shows That the Properties of VSL#3 Depend from Where it is Manufactured

, 2019; 19(2): 199 - 206

Paola Palumbo*, Francesca Lombardi, Maria Grazia Cifone and Benedetta Cinque





Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study

, 2019; 19(1): 75 - 83

Luís Raposo*, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos




Pioglitazone Therapy and Fractures: Systematic Review and Meta- Analysis

, 2018; 18(5): 502 - 507

Velichka Pavlova*, Elena Filipova, Katya Uzunova, Krassimir Kalinov and Toni Vekov




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Assessment of Response to Treatment and Follow-Up in Gastroenteropancreatic Neuroendocrine Neoplasms

, 2018; 18(5): 419 - 449

Franco Grimaldi*, Nicola Fazio*, Roberto Attanasio, Andrea Frasoldati, Enrico Papini, Nadia Cremonini, Maria V. Davi, Luigi Funicelli, Sara Massironi, Francesca Spada, Vincenzo Toscano, Annibale Versari, Michele Zini, Massimo Falconi and Kjell Oberg




Shift from Levothyroxine Tablets to Liquid Formulation at Breakfast Improves Quality of Life of Hypothyroid Patients

, 2018; 18(3): 235 - 240

Rinaldo Guglielmi, Franco Grimaldi, Roberto Negro, Andrea Frasoldati, Irene Misischi, Filomena Graziano, Claudia Cipri, Edoardo Guastamacchia, Vincenzo Triggiani* and Enrico Papini




GH Supplementation Effects on Cardiovascular Risk in GH Deficient Adult Patients: A Systematic Review and Meta-analysis

, 2017; 17(4): 285 - 296

Vito A. Giagulli*, Marco Castellana, Raffaella Perrone, Edoardo Guastamacchia, Massimo Iacoviello and Vincenzo Triggiani




Cerebral Hypoperfusion in Hereditary Coproporphyria (HCP): A Single Photon Emission Computed Tomography (SPECT) Study

, 2016; 16(1): 39 - 46

Guido Valle, Claudio Carmine Guida, Michelangelo Nasuto, Manuela Totaro, Filippo Aucella, Vincenzo Frusciante, Lazzaro Di Mauro, Adele Potenza, Maria Savino, Mario Stanislao, Teresa Popolizio, Giuseppe Guglielmi, Vito Angelo Giagulli, Edoardo Guastamacchia and Vincenzo Triggiani





Thalidomide Controls Adipose Tissue Inflammation Associated with High- Fat Diet-Induced Obesity in Mice

, 2015; 15(2): 151 - 158

Patricia Z Nakamitsu, Cecilia M. Compri, Livia de Fraia Pinto, Erica M.F. Gotardo, Caroline C. de Oliveira, Marcelo L. Ribeiro, Jose Pedrazzoli and Alessandra Gambero




Vitamins and Type 2 Diabetes Mellitus

, 2015; 15(1): 54 - 63

Roxana Valdes-Ramos, Guadarrama-Lopez A. Laura, Martinez-Carrillo B. Elina and Benitez-Arciniega A. Donaji




Neutrophil Derived Microvesicles: Emerging Role of a Key Mediator to the Immune Response

, 2014; 14(3): 210 - 217

Bobby L. Johnson, III, Josh W. Kuethe and Charles C. Caldwell




Recent Advances in the Understanding of Sepsis-Induced Alterations in the Neuroendocrine System

, 2013; 13(4): 335 - 347

Fazal Wahab, Bibi Atika, Gabriela R. Oliveira-Pelegrin and Maria J. A. Rocha






Most Cited Articles

The use of Immunoglobulin Therapy in Primary Immunodeficiency Diseases

, 2016; 16(2): 80-88.

Gholamreza Azizi, Hassan Abolhassani, Mohammad Hosein Asgardoon, Javad Rahnavard, Majid Zaki dizaji, Reza Yazdani, Javad Mohammadi and Asghar Aghamohammadi


DOI: 10.2174/1871530316666160724214418



Thyroid Hormones, Metabolic Syndrome and Its Components

, 2017; 17(1): 56-62.

Alessandro P. Delitala*, Giuseppe Fanciulli, Giovanni M. Pes, Margherita Maioli and Giuseppe Delitala


DOI: 10.2174/1871530317666170320105221




The Association of Folic Acid Deficiency and Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus

, 2016; 16(2): 120-123.

Sonny Bherwani, A.S. Saumya, Ashok Kumar Ahirwar, A.S. Sandhya, Brijesh Prajapat, Sitendu Patel, Ritu Singh and L.H. Ghotekar


DOI: 10.2174/1871530316666160415155934


Hypoxia and Inflammation in Prostate Cancer Progression. Cross-talk with Androgen and Estrogen Receptors and Cancer Stem Cells

, 2016; 16(4): 235-248.

Matteo Antonio Russo, Linda Ravenna, Laura Pellegrini, Elisa Petrangeli, Luisa Salvatori, Thea Magrone, Massimo Fini and Marco Tafani


DOI: 10.2174/1871530316666161130160144


Immune-Neuroendocrine Dysregulation in Patients with Osteoarthritis: A Revision and a Pilot Study

, 2017; 17(1): 78-85.

Isabel Galvez, Silvia Torres-Piles, Maria D. Hinchado, Alberto Alvarez-Barrientos, Pilar Torralbo-Jimenez, Jorge Guerrero, Leticia Martin-Cordero and Eduardo Ortega*


DOI: 10.2174/1871530317666170320113613


The Gender Bender effect in Periodontal Immune Response

, 2016; 16(1): 12-20.

Vishakha Grover, Ashish Jain, Anoop Kapoor, Ranjan Malhotra and Gurparkash Singh Chahal


DOI: 10.2174/1871530316666160107111301


In Vitro Effects of Nickel on Healthy Non-Allergic Peripheral Blood Mononuclear Cells. The Role of Red Grape Polyphenols

, 2017; 17(2): 166-173.

Thea Magrone*, Rosaria Salvatore, Anna Spagnoletta, Manrico Magrone, Matteo Antonio Russo and Emilio Jirillo


DOI: 10.2174/1871530317666170713145350



Most Accessed Articles







Neuropsychiatric Aspects in Men with Klinefelter Syndrome

, 2019; 19(2): 109-115.

Vito Angelo Giagulli*, Beatrice Campone, Marco Castellana, Ciro Salzano, Alessandra Daphne Fisher, Cristina de Angelis, Rosario Pivonello, Annamaria Colao, Daniela Pasquali, Mario Maggi, Vincenzo Triggiani and On behalf of the Klinefelter ItaliaN Group (KING)


DOI: 10.2174/1871530318666180703160250


Successful Treatment for Severe Thyroid-associated Ophthalmopathy with Tocilizumab

, 2018; 18(6): 665-667.

Carlos A. Canas*, Fabio Bonilla-Abadia, Katherine Vallejo, Hector M. Rengifo, Marco A. Gallon and Gabriel J. Tobon


DOI: 10.2174/1871530318666180702150243


Hypoglycemic and Hypolipemic Effects of a New Lecithin Formulation of Bergamot Polyphenolic Fraction: A Double Blind, Randomized, Placebo- Controlled Study

, 2019; 19(2): 136-143.

Vincenzo Mollace*, Miriam Scicchitano, Sara Paone, Francesca Casale, Carla Calandruccio, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Saverio Nucera, Antonella Riva, Pietro Allegrini, Massimo Ronchi, Giovanna Petrangolini and Ezio Bombardelli


DOI: 10.2174/1871530319666181203151513





Editor-in-Chief

Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
Italy

Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.
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Scopus CiteScore Metrics: 1.93



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