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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

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    Chemistry, Medicinal

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Contents

Current Topics in Medicinal Chemistry, Volume 18 - Number 17

Perspectives in Medicinal Chemistry   Open Access


Editorial   Open Access

Synthesis and Biological Profiles of 1,2,3-Triazole Scaffold

, 18(17): 1426 - 1427

Fernando de Carvalho da Silva, Vitor Francisco Ferreira and Luana da Silva Magalhães Forezi


DOI: 10.2174/156802661817181107151553


Review Article

Alternative Routes to the Click Method for the Synthesis of 1,2,3-Triazoles, an Important Heterocycle in Medicinal Chemistry

, 18(17): 1428 - 1453

Luana da S.M. Forezi, Mariana F.C. Cardoso, Daniel T.G. Gonzaga, Fernando de C. da Silva* and Vitor F. Ferreira*


DOI: 10.2174/1568026618666180821143902



Research Article

Design, Synthesis and Antileishmanial Activity of Naphthotriazolyl-4- Oxoquinolines

, 18(17): 1454 - 1464

Vanessa G. Oliveira*, Viviane dos Santos Faiões, Gabrieli B.R. Gonçalves, Miriam F.O. Lima, Fernanda C.S. Boechat, Anna C. Cunha, Valter V. de Andrade-Neto, Fernando de C. da Silva, Eduardo C. Torres-Santos* and Maria Cecília B.V. de Souza*


DOI: 10.2174/1568026618666181002110116



Research Article

A Novel Naphthotriazolyl-4-oxoquinoline Derivative that Selectively Controls Breast Cancer Cells Survival Through the Induction of Apoptosis

, 18(17): 1465 - 1474

Jessica R. Branco, Vanessa G. Oliveira, Amanda M. Esteves, Ingrid C. Chipoline, Miriam F.O. Lima, Fernanda C.S. Boechat, Fernando C. da Silva, Vítor F. Ferreira, Mauro Sola-Penna, Maria C.B.V. de Souza* and Patricia Zancan*


DOI: 10.2174/1568026618666180821142458



Research Article

Novel Symmetrical 1,4-Disubstituted-bis-1,2,3-Triazoles: Synthesis by Double CuAAC and Cytotoxicity Evaluation

, 18(17): 1475 - 1482

Wallace J. Reis, Paulo O.L. Moreira, Rosemeire B. Alves, Heloísa H.M. Oliveira, Luciana M. Silva, Fernando P. Varotti and Rossimiriam P. Freitas*


DOI: 10.2174/1568026618666181022124847



Research Article

A Novel Triazole Derivative Drug Presenting In Vitro and In Vivo Anticancer Properties

, 18(17): 1483 - 1493

Ricardo Imbroisi Filho, Daniel T.G. Gonzaga, Thainá M. Demaria, João G.B. Leandro, Dora C.S. Costa, Vitor F. Ferreira, Mauro Sola-Penna, Fernando de C. da Silva* and Patricia Zancan*


DOI: 10.2174/1568026618666180917100640



Research Article

New Efavirenz Derivatives and 1,2,3-Triazolyl-phosphonates as Inhibitors of Reverse Transcriptase of HIV-1

, 18(17): 1494 - 1505

Carolina C.P. Costa, Nubia Boechat*, Monica M. Bastos, Fernando de C. da Silva, Andressa Marttorelli, Thiago M.L. Souza, Mayara S. Baptista, Lucas V.B. Hoelz and Ernesto R. Cafffarena


DOI: 10.2174/1568026618666181029150118



Research Article

Oxazolone–1,2,3-Triazole Hybrids: Design, Synthesis and Antimicrobial Evaluation

, 18(17): 1506 - 1513

Kashmiri Lal*, Lokesh Kumar, Ashwani Kumar and Anil Kumar


DOI: 10.2174/1568026618666180913110456




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