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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

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  • 18th of 59 in

    Chemistry, Medicinal

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Open Access Articles











InsP3 Signaling in Apicomplexan Parasites

, 2017; 17(19): 2158 - 2165

Celia R.S. Garcia*, Eduardo Alves, Pedro H. S. Pereira, Paula J. Bartlett, Andrew P. Thomas, Katsuhiko Mikoshiba, Helmut Plattner and L. David Sibley








Copper Homeostasis for the Developmental Progression of Intraerythrocytic Malarial Parasite

, 2016; 16(27): 3048 - 3057

Hiroko Asahi, Fumie Kobayashi, Shin-Ichi Inoue, Mamoru Niikura, Kenji Yagita and Mohammed Essa Marghany Tolba






HCN Channels Modulators: The Need for Selectivity

, 2016; 16(16): 1764 - 1791

Maria Novella Romanelli, Laura Sartiani, Alessio Masi, Guido Mannaioni, Dina Manetti, Alessandro Mugelli and Elisabetta Cerbai










Toxicity of 11 Metal Oxide Nanoparticles to Three Mammalian Cell Types In V itro

, 2015; 15(18): 1914 - 1929

Angela Ivask, Tiina Titma, Meeri Visnapuu, Heiki Vija, Aleksandr Kakinen, Mariliis Sihtmae, Suman Pokhrel, Lutz Madler, Margit Heinlaan, Vambola Kisand, Ruth Shimmo and Anne Kahru




Computer-Aided Drug Design of Bioactive Natural Products

, 2015; 15(18): 1780 - 1800

Veda Prachayasittikul, Apilak Worachartcheewan, Watshara Shoombuatong, Napat Songtawee, Saw Simeon, Virapong Prachayasittikul and Chanin Nantasenamat







Intracellular Redox State as Target for Anti-Influenza Therapy: Are Antioxidants Always Effective?

, 2014; 14(22): 2529 - 2541

Rossella Sgarbanti, Donatella Amatore, Ignacio Celestino, Maria Elena Marcocci, Alessandra Fraternale, Maria Rosa Ciriolo, Mauro Magnani, Raffaele Saladino, Enrico Garaci, Anna Teresa Palamara and Lucia Nencioni



















Therapy in Prion Diseases

, 2013; 13(19): 2465 - 2476

Gianluigi Forloni, Vladimiro Artuso, Ignazio Roiter, Michela Morbin and Fabrizio Tagliavini







Mitochondria: A Promising Target for Anticancer Alkaloids

, 2013; 13(17): 2171 - 2183

Félix A. Urra, Miguel Cordova-Delgado, Hernan Pessoa-Mahana, Oney Ramírez-Rodríguez, Boris Weiss-Lopez, Jorge Ferreira and Ramiro Araya-Maturana











The Emerging Role of microRNA in Stroke

, 2013; 13(13): 1573 - 1588

Georgios Koutsis, Gerasimos Siasos and Konstantinos Spengos










Open Source Software and Web Services for Designing Therapeutic Molecules

, 2013; 13(10): 1172 - 1191

Deepak Singla, Sandeep Kumar Dhanda, Jagat Singh Chauhan, Anshu Bhardwaj, Samir K. Brahmachari, Open Source Drug Discovery Consortium and Gajendra P.S. Raghava








Medicinal Chemistry Design Principles for Liver Targeting Through OATP Transporters

, 2013; 13(7): 857 - 866

Meihua Tu, Alan M. Mathiowetz, Jeffrey A. Pfefferkorn, Kimberly O. Cameron, Robert L. Dow, John Litchfield, Li Di, Bo Feng and Spiros Liras




Intestinal Targeting of Drugs: Rational Design Approaches and Challenges

, 2013; 13(7): 776 - 802

Kevin J. Filipski, Manthena V. Varma, Ayman F. El-Kattan, Catherine M. Ambler, Roger B. Ruggeri, Theunis C. Goosen and Kimberly O. Cameron








The Impact of Computer Science in Molecular Medicine: Enabling High- Throughput Research

, 2013; 13(5): 526 - 575

Diana de la Iglesia, Miguel Garcia-Remesal, Guillermo de la Calle, Casimir Kulikowski, Ferran Sanz and Victor Maojo






Endogenous Modulators of TRP Channels

, 2013; 13(3): 398 - 407

Enza Palazzo, Francesco Rossi, Vito de Novellis and Sabatino Maione




Oncogenic and Anti-Oncogenic Effects of Transient Receptor Potential Channels

, 2013; 13(3): 344 - 366

Sonia Liberati, Maria Beatrice Morelli, Massimo Nabissi, Matteo Santoni and Giorgio Santoni




MicroRNAs and the Heart: Small Things Do Matter

, 2013; 13(2): 216 - 230

Nikolaos Papoutsidakis, Spyridon Deftereos, Andreas Kaoukis, Georgios Bouras, Georgios Giannopoulos, Andreas Theodorakis, Christos Angelidis, Georgios Hatzis and Christodoulos Stefanadis




Myeloperoxidase: Expressing Inflammation and Oxidative Stress in Cardiovascular Disease

, 2013; 13(2): 115 - 138

Nikolaos Anatoliotakis, Spyridon Deftereos, Georgios Bouras, Georgios Giannopoulos, Dimitrios Tsounis, Christos Angelidis, Andreas Kaoukis and Christodoulos Stefanadis




Computational Tools in the Discovery of New G-Quadruplex Ligands with Potential Anticancer Activity

, 2012; 12(24): 2843 - 2856

Daimel Castillo-Gonzalez, Gisselle Perez-Machado, Federico Pallardo, Teresa-Maria Garrigues-Pelufo and Miguel-Angel Cabrera-Perez






Alpha-Emitters for Immuno-Therapy: A Review of Recent Developments from Chemistry to Clinics

, 2012; 12(23): 2642 - 2654

Sandrine Huclier-Markai, Cyrille Alliot, Nicolas Varmenot, Cathy S. Cutler and Jacques Barbet




SOD1 Aggregation and ALS: Role of Metallation States and Disulfide Status

, 2012; 12(22): 2560 - 2572

Yuewei Sheng, Madhuri Chattopadhyay, Julian Whitelegge and Joan Selverstone Valentine









Monoamine Oxidase Inhibitors: Ten Years of Docking Studies

, 2012; 12(20): 2145 - 2162

Giulio Ferino, Santiago Vilar, Maria J. Matos, Eugenio Uriarte and Enzo Cadoni




Effects of Natural Compounds on Xenopus Embryogenesis: A Potential Read Out for Functional Drug Discovery Targeting Wnt/β-catenin Signaling

, 2012; 12(19): 2103 - 2113

Nathalia G. Amado, Barbara F. Fonseca, Debora Malta Cerqueira, Alice H. Reis, Alessandro Bolis Costa Simas, Ricardo Machado Kuster, Fabio A. Mendes and Jose G. Abreu







Enzyme Informatics

, 2012; 12(17): 1911 - 1923

Rosanna G. Alderson, Luna De Ferrari, Lazaros Mavridis, James L. McDonagh, John B.O. Mitchell and Neetika Nath










Towards Isozyme-Selective HDAC Inhibitors For Interrogating Disease

, 2012; 12(14): 1479 - 1499

Praveer Gupta, Robert C. Reid, Abishek Iyer, Matthew J. Sweet and David P. Fairlie








The IC50 Concept Revisited

, 2012; 12(11): 1282 - 1290

Gary W. Caldwell, Zhengyin Yan, Wensheng Lang and John A. Masucci





Novel Therapeutic Approaches Targeting Matrix Metalloproteinases in Cardiovascular Disease

, 2012; 12(10): 1214 - 1221

Alexandros Briasoulis, Dimitris Tousoulis, Nikolaos Papageorgiou, Anna-Maria Kampoli, Emmanuel Androulakis, Charalambos Antoniades, Eleftherios Tsiamis, George Latsios and Christodoulos Stefanadis




Myocardial Structure and Matrix Metalloproteinases

, 2012; 12(10): 1113 - 1131

C. Aggeli, P. Pietri, I. Felekos, L. Rautopoulos, K. Toutouzas, E. Tsiamis and C. Stefanadis





















Polymeric Carrier Systems for siRNA Delivery

, 2012; 12(2): 108 - 119

P. Vader, L. J. van der Aa, G. Storm, R. M. Schiffelers and J. F.J. Engbersen





Rapid Analysis of Pharmacology for Infectious Diseases

, 2011; 11(10): 1292 - 1300

Andrew L. Hopkins, G. Richard Bickerton, Ian M. Carruthers, Stephen K. Boyer, Harvey Rubin and John P. Overington






IRAK-4 Inhibitors for Inflammation

, 2009; 9(8): 724 - 737

Zhulun Wang, Holger Wesche, Tracey Stevens, Nigel Walker and Wen-Chen Yeh




Melanocortins in the Treatment of Male and Female Sexual Dysfunction

, 2007; 7(11): 1137 - 1144

Trevor J. Hallam, Carl Spana, Dennis C. Earle, Annette M. Shadiack and Shubh D. Sharma







Editor-in-Chief

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who is the current Editor-in-Chief serving since 2001.
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Scopus CiteScore Metrics: 2.97


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