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Current Topics in Medicinal Chemistry

Volume 19, 32 Issues, 2019
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

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  • 18th of 59 in

    Chemistry, Medicinal

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Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

, 2018; 18(4): 256 - 274

Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao


DOI: 10.2174/1568026618666180410151518


Aurora Kinase Inhibitors in Head and Neck Cancer

, 2018; 18(3): 199 - 213

Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*


DOI: 10.2174/1568026618666180112163741



New Benzothiazole-based Thiazolidinones as Potent Antimicrobial Agents. Design, synthesis and Biological Evaluation

, 2018; 18(1): 75 - 87

Michelyne Haroun*, Christophe Tratrat, Katerina Kositzi, Evangelia Tsolaki, Anthi Petrou, Bandar Aldhubiab, Mahesh Attimarad, Sree Harsha, Athina Geronikaki*, Katharigatta N. Venugopala, Heba S. Elsewedy, Marina Sokovic, Jasna Glamoclija and Ana Ciric


DOI: 10.2174/1568026618666180206101814



Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease

, 2016; 16(17): 1951 - 1960

Nady Braidy, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Hussein Mansour, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant


DOI: 10.2174/1568026616666160204121431


Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

, 2016; 16(16): 1792 - 1818

Robert A. Pearlstein, K. Andrew MacCannell, Gül Erdemli, Sarita Yeola, Gabriel Helmlinger, Qi-Ying Hu, Ramy Farid, William Egan, Steven Whitebread, Clayton Springer, Jeremy Beck, Hao-Ran Wang, Mateusz Maciejewski, Laszlo Urban and José S. Duca


DOI: 10.2174/1568026616666160315142156



Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

, 2016; 16(14): 1610 - 1630

Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi


DOI: 10.2174/1568026616666151223113540


















Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration

, 2015; 15(21): 2116 - 2138

Caio Henrique Mazucanti, Joao Victor Cabral-Costa, Andrea Rodrigues Vasconcelos, Diana Zukas Andreotti, Cristoforo Scavone and Elisa Mitiko Kawamoto


DOI: 10.2174/1568026615666150610125715


From Protein Communication to Drug Discovery

, 2015; 15(20): 2019 - 2031

Marco Persico, Antonio Di Dato, Nausicaa Orteca, Caterina Fattorusso, Ettore Novellino, Mirko Andreoli and Cristiano Ferlini


DOI: 10.2174/1568026615666150519102257


Biological Function and Medicinal Research Significance of G-Quadruplex Interactive Proteins

, 2015; 15(19): 1971 - 1987

Jun Qiu, Mingxue Wang, Yan Zhang, Ping Zeng, Tian-Miao Ou, Jia-Heng Tan, Shi-Liang Huang, Lin-Kun An, Honggen Wang, Lian-Quan Gu, Zhi-Shu Huang and Ding Li


DOI: 10.2174/1568026615666150515150803


Computer-Aided Drug Design of Bioactive Natural Products

, 2015; 15(18): 1780 - 1800

Veda Prachayasittikul, Apilak Worachartcheewan, Watshara Shoombuatong, Napat Songtawee, Saw Simeon, Virapong Prachayasittikul and Chanin Nantasenamat


DOI: 10.2174/1568026615666150506151101



Magnetite: From Synthesis to Applications

, 2015; 15(16): 1622 - 1640

Gozde Unsoy, Ufuk Gunduz, Ovidiu Oprea, Denisa Ficai, Maria Sonmez, Marius Radulescu, Mihaela Alexie and Anton Ficai


DOI: 10.2174/1568026615666150414153928








Cardiovascular Effects of Coumarins Besides their Antioxidant Activity

, 2015; 15(9): 830 - 849

Iveta Najmanova, Martin Dosedel, Radomir Hrdina, Pavel Anzenbacher, Tomas Filipsky, Michal Riha and Premysl Mladenka


DOI: 10.2174/1568026615666150220112437























Tuning hERG Out: Antitarget QSAR Models for Drug Development

, 2014; 14(11): 1399 - 1415

Rodolpho C. Braga, Vinicius M. Alves, Meryck F.B. Silva, Eugene Muratov, Denis Fourches, Alexander Tropsha and Carolina H. Andrade


DOI: 10.2174/1568026614666140506124442




Indole Alkaloids and Semisynthetic Indole Derivatives as Multifunctional Scaffolds Aiming the Inhibition of Enzymes Related to Neurodegenerative Diseases – A Focus on Psychotria L. Genus

, 2014; 14(8): 1056 - 1075

Luiz Carlos Klein-Junior, Carolina dos Santos Passos, Aline Pereira Moraes, Vinicius Galvao Wakui, Eduardo Luis Konrath, Alessandra Nurisso, Pierre-Alain Carrupt, Cecilia Maria Alves de Oliveira, Lucilia Kato and Amelia Teresinha Henriques


DOI: 10.2174/1568026614666140324142409










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