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Current Topics in Medicinal Chemistry

Volume 20, 32 Issues, 2020
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.

Current Topics in Medicinal Chemistry

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Volume 20

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Number 29



Editorial   Open Access



Research Article



Review Article



Research Article



Review Article



Review Article



Research Article



Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 32


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 31


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 20 (2020) - Number 30


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print




The Anticancer Activity of Indazole Compounds: A Mini Review


Congshan Shang*, Yani Hou, Tingting Meng, Min Shi* and Guoyan Cui


DOI: 10.2174/1568026620999201124154231
View Abstract




4-Aryl-1,4-Dihydropyridines as Potential Enoyl-Acyl Carrier Protein Reductase Inhibitors: Antitubercular Activity and Molecular Docking Study


Katharigatta N. Venugopala*, Christophe Tratrat, Melendhran Pillay, Pran Kishore Deb, Deepak Chopra, Sandeep Chandrashekharappa, Michelyne Haroun, Mohamed A. Morsy, Bandar E. Aldhubiab, Mahesh Attimarad, Anroop B. Nair, Nagaraja Sreeharsha, Mahmoud Kandeel, Rashmi Venugopala and Viresh Mohanlall


DOI: 10.2174/1568026620666201102121606
View Abstract View on PubMed





Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Parallelization of Molecular Docking: A Review

, 2018; 18(12): 1015 - 1028

Dong Dong, Zhijian Xu, Wu Zhong and Shaoliang Peng*


DOI: 10.2174/1568026618666180821145215




A Review on Plant Antimicrobials of Past Decade

, 2018; 18(10): 812 - 833

Preet Amol Singh, Sapna D. Desai and Jasbir Singh*


DOI: 10.2174/1568026618666180516123229




Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

, 2018; 18(8): 714 - 746

Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*


DOI: 10.2174/1568026618666180604082610






Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

, 2018; 18(4): 256 - 274

Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao


DOI: 10.2174/1568026618666180410151518



Aurora Kinase Inhibitors in Head and Neck Cancer

, 2018; 18(3): 199 - 213

Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*


DOI: 10.2174/1568026618666180112163741



Open Access Articles

Peptide Receptor Radionuclide Therapy: Looking Back, Looking Forward

, 2020; 20(32): 2959 - 2969

Danny Feijtel, Marion de Jong and Julie Nonnekens*




Learning the Edit Costs of Graph Edit Distance Applied to Ligand-Based Virtual Screening

, 2020; 20(18): 1582 - 1592

Carlos Garcia-Hernandez, Alberto Fernández* and Francesc Serratosa




Telomere-related Markers for Cancer

, 2020; 20(6): 410 - 432

Xiaotian Yuan*, Mingkai Dai and Dawei Xu*






Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

, 2019; 19(18): 1621 - 1649

Kenji Maeda*, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura and Hiroaki Takeuchi*




Targeting the PAC1 Receptor for Neurological and Metabolic Disorders

, 2019; 19(16): 1399 - 1417

Chenyi Liao, Mathilde P. de Molliens, Severin T. Schneebeli, Matthias Brewer, Gaojie Song, David Chatenet, Karen M. Braas, Victor May* and Jianing Li*




Ensemble-Based Modeling of Chemical Compounds with Antimalarial Activity

, 2019; 19(11): 957 - 969

Ana Yisel Caballero-Alfonso, Maykel Cruz-Monteagudo, Eduardo Tejera, Emilio Benfenati, Fernanda Borges, M. Natália D.S. Cordeiro, Vinicio Armijos-Jaramillo and Yunierkis Perez-Castillo*





Treatment of Toxoplasmosis and Neosporosis in Farm Ruminants: State of Knowledge and Future Trends

, 2018; 18(15): 1304 - 1323

Roberto Sánchez-Sánchez, Patricia Vázquez, Ignacio Ferre and Luis Miguel Ortega-Mora*




Mechanical Properties of Composite Hydrogels for Tissue Engineering

, 2018; 18(14): 1214 - 1223

Ramon Rial, J.F. Armando Soltero, Pedro V. Verdes, Zhen Liu and Juan M. Ruso*





Analyzing of Molecular Networks for Human Diseases and Drug Discovery

, 2018; 18(12): 1007 - 1014

Tong Hao, Qian Wang, Lingxuan Zhao, Dan Wu, Edwin Wang* and Jinsheng Sun*




Toward Reproducible Results from Targeted Metabolomic Studies: Perspectives for Data Pre-processing and a Basis for Analytic Pipeline Development

, 2018; 18(11): 883 - 895

Thomas Gross, Mark Mapstone, Ricardo Miramontes, Robert Padilla, Amrita K. Cheema, Fabio Macciardi, Howard J. Federoff* and Massimo S. Fiandaca*






Most Cited Articles


Review Article

Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases

, 2019; 19(19): 1694-1711.

Viktoriya Ivasiv, Claudia Albertini, Ana E. Gonçalves, Michele Rossi and Maria L. Bolognesi*


DOI: 10.2174/1568026619666190619115735



Review Article

Biological activities of artemisinin derivatives beyond malaria

, 2019; 19(3): 205-222.

Xiaoyan Liu, Jianguo Cao, Guozheng Huang*, Qingjie Zhao* and Jingshan Shen


DOI: 10.2174/1568026619666190122144217


Review Article

Mycobacterial tuberculosis Enzyme Targets and their Inhibitors

, 2019; 19(5): 337-355.

Anil Kumar Saxena* and Anamika Singh


DOI: 10.2174/1568026619666190219105722


Review Article

Biological signatures of alzheimer’s disease

, 2020; 20(9): 770-781.

Poornima Sharma, Anjali Sharma, Faizana Fayaz, Sharad Wakode* and Faheem H. Pottoo


DOI: 10.2174/1568026620666200228095553


Review Article

Emerging complexity and the need for advanced drug delivery in targeting Candida species

, 2019; 19(28): 2593-2609.

Ridhima Wadhwa, Parijat Pandey, Gaurav Gupta, Taru Aggarwal, Nitesh Kumar, Meenu Mehta, Saurabh Satija, Monica Gulati, Jyotsna Madan, Harish Dureja, Sri R. Balusamy, Haribalan Perumalsamy, Pawan K. Maurya, Trudi Collet, Murtaza M. Tambuwala, Philip M. Hansbro, Dinesh Kumar Chellappan* and Kamal Dua*


DOI: 10.2174/1568026619666191026105308


Review Article

Nanoparticle therapy for prostate cancer: Overview and perspectives

, 2019; 19(1): 57-73.

Junfu Zhang, Liying Wang, Xinru You, Tuzeng Xian, Jun Wu* and Jun Pang*


DOI: 10.2174/1568026619666190125145836



Perspectives in Medicinal Chemistry

Functional inhibition of VEGF and EGFR suppressors in cancer treatment

, 2019; 19(3): 178-179.

Sanjeev Kumar Singh and Anuraj Nayarisseri


DOI: 10.2174/156802661903190328155731




Review Article

Virtual screening techniques in drug discovery: Review and recent applications

, 2019; 19(19): 1751-1767.

Sheisi F.L. da Silva Rocha, Carolina G. Olanda, Harold H. Fokoue and Carlos M.R. Sant'Anna*


DOI: 10.2174/1568026619666190816101948


Review Article

STAT3: A potential drug target for tumor and inflammation

, 2019; 19(15): 1305-1317.

Yang Sheng Hu, Xu Han and Xin Hua Liu*


DOI: 10.2174/1568026619666190620145052


Research Article

Identification of high-affinity small molecules targeting Gamma secretase for the treatment of Alzheimer’s disease

, 2019; 19(13): 1173-1187.

Meer Asif Ali, Sugunakar Vuree, Himshikha Goud, Tajamul Hussain, Anuraj Nayarisseri* and Sanjeev Kumar Singh*


DOI: 10.2174/1568026619666190617155326



Most Accessed Articles


Allosteric Modulators for the Treatment of Schizophrenia: Targeting Glutamatergic Networks

, 2013; 13(1): 26-54.

Frank S. Menniti, Craig W. Lindsley, P. Jeffrey Conn, Jayvardhan Pandit, Panayiotis Zagouras and Robert A. Volkmann


DOI: 10.2174/1568026611313010005


Computational Approaches to Model Ligand Selectivity in Drug Design

, 2006; 6(1): 41-55.

Angel R. Ortiz, Paulino Gomez-Puertas, Alejandra Leo-Macias, Pedro Lopez-Romero, Eduardo Lopez-Vinas, Antonio Morreale, Marta Murcia and Kun Wang


DOI: 10.2174/156802606775193338





Akt Pathway Inhibitors

, 2020; 20(10): 883-900.

Nne E. Uko, Osman F. Güner, Diane F. Matesic and J. Phillip Bowen*


DOI: 10.2174/1568026620666200224101808


Recent Development of Small Molecule Glutaminase Inhibitors

, 2018; 18(6): 432-443.

Minsoo Song*, Soong-Hyun Kim, Chun Young Im and Hee-Jong Hwang


DOI: 10.2174/1568026618666180525100830



Editor-in-Chief

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
(USA)
Biography
View Full Editorial Board

COPE Compliant

Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who is the current Editor-in-Chief serving since 2001.

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