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Forthcoming Special Issues

Current Adances in Applied Neuroscience Research


Guest Editor(s): Drozdstoy St. Stoyanov
Tentative Publication Date: October, 2018
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Special Issues - In-Press
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Published Special Issues

Medicinal Chemistry of Farnesoid X Receptor (FXR) Modulators: The-State-of-the-Art


Guest Editor(s): Maura Marinozzi

Authors' Comments
It has been a great experience publishing my research work with Bentham Science Publishers. The editorial board is very professional. I would highly recommend the journal “Current Topics in Medicinal Chemistry” to my colleagues.

Maité Sylla-Iyarreta Veitía
(Equipe de chimie moléculaire, Laboratoire de Chimie moléculaire, génie des procédés chimiques et énergétiques, EA7341, Conservatoire national des arts et métiers, 2 rue Conté, 75003, Paris, France)


Current Topics in Medicinal Chemistry

,

Volume 18

-

Number 12



Editorial   Open Access



Review Article

Network Pharmacology: Exploring the Resources and Methodologies

, 18(12): 949 - 964

Junaid Muhammad, Abbas Khan , Arif Ali , Li Fang, Wang Yanjing, Qin Xu and Dong-Qing Wei *


DOI: 10.2174/1568026618666180330141351




Review Article

Discovering Synergistic Drug Combination from a Computational Perspective

, 18(12): 965 - 974

Pingjian Ding, Jiawei Luo*, Cheng Liang, Qiu Xiao , Buwen Cao and Guanghui Li


DOI: 10.2174/1568026618666180330141804




Review Article

Role of Noncoding RNA in Pulmonary Arterial Hypertension and Potential Drug Therapeutic Target

, 18(12): 975 - 986

Chi-yuan Zhang, Mo liu, Jia-ming Wan, Ming-qi Gao, Yue Zhang, Muscab Soyan, Huai-Liang Wang and Yang Bai*


DOI: 10.2174/1568026618666180719162124




Review Article

Applications of Machine Learning Methods in Drug Toxicity Prediction

, 18(12): 987 - 997

Li Zhang, Hui Zhang, Haixin Ai, Huan Hu, Shimeng Li, Jian Zhao and Hongsheng Liu*


DOI: 10.2174/1568026618666180727152557




Review Article



Review Article

Analyzing of Molecular Networks for Human Diseases and Drug Discovery

, 18(12): 1007 - 1014

Tong Hao, Qian Wang, Lingxuan Zhao, Dan Wu, Edwin Wang* and Jinsheng Sun*


DOI: 10.2174/1568026618666180813143408




Review Article



Current Topics in Medicinal Chemistry, Volume 18 (2018) - Number 14


This issue is in progress but contains articles that are final and fully citable.

Current Topics in Medicinal Chemistry, Volume 18 (2018) - Number 13


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

A Novel Naphthotriazolyl-4-oxoquinoline Derivative that Selectively Controls Breast Cancer Cells Survival Through the Induction of Apoptosis


Jessica R. Branco, Vanessa G. Oliveira, Amanda M. Esteves, Ingrid C. Chipoline, Miriam F. O. Lima, Fernanda C. S. Boechat, Fernando C. da Silva, Vitor F. Ferreira, Mauro Sola-Penna, Maria C. B. V. de Souza* and Patricia Zancan*


View Abstract View on PubMed





Immunometabolism in the Pathogenesis of Depressive Disorders - Therapeutic Considerations


Dietmar Fuchs*, Simon Geisler, Barbara Sperner-Unterweger and Johanna M. Gostner


View Abstract View on PubMed


Abstracts Ahead of Print

A novel triazole derivative drug presenting in vitro and in vivo anticancer properties


Ricardo Imbroisi Filho, Daniel T. G. Gonzaga, Thaina M. Demaria, Joao G.B. Leandro, Dora C.S. Costa, Vitor F. Ferreira, Mauro Sola-Penna, Fernando de C. da Silva* and Patricia Zancan*


View Abstract



Alternative Routes to the Click Method for the Synthesis of 1,2,3-Triazoles


Luana da S. M. Forezi, Mariana F. C. Cardoso, Daniel T. G. Gonzaga, Fernando de C. da Silva and Vitor F. Ferreira*


View Abstract


Editor's Choice

The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use

, 2016; 16(18): 1976 - 1989

Daniel Iglesias, Susanna Bosi, Michele Melchionna, Tatiana Da Ros and Silvia Marchesan


DOI: 10.2174/1568026616666160215154807



Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease

, 2016; 16(17): 1951 - 1960

Nady Braidy, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Hussein Mansour, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant


DOI: 10.2174/1568026616666160204121431



Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

, 2016; 16(16): 1792 - 1818

Robert A. Pearlstein, K. Andrew MacCannell, Gül Erdemli, Sarita Yeola, Gabriel Helmlinger, Qi-Ying Hu, Ramy Farid, William Egan, Steven Whitebread, Clayton Springer, Jeremy Beck, Hao-Ran Wang, Mateusz Maciejewski, Laszlo Urban and José S. Duca


DOI: 10.2174/1568026616666160315142156




Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

, 2016; 16(14): 1610 - 1630

Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi


DOI: 10.2174/1568026616666151223113540




Current Drug Discovery for Anti-hepatitis C Virus Targeting NS4B

, 2016; 16(12): 1362 - 1371

Zhenya Wang, Xinli Chen, Chunli Wu, Haiwei Xu and Hongmin Liu


DOI: 10.2174/1568026616666151120112642



Bispidine as a Privileged Scaffold

, 2016; 16(11): 1314 - 1342

Isabelle Tomassoli and Daniela Gündisch


DOI: 10.2174/1568026615666150915111434





Open Access Articles


Metabolomics Applications in Precision Medicine: An Oncological Perspective

, 2017; 17(24): 2740 - 2751

Leonor Puchades-Carrasco and Antonio Pineda- Lucena*




InsP3 Signaling in Apicomplexan Parasites

, 2017; 17(19): 2158 - 2165

Celia R.S. Garcia*, Eduardo Alves, Pedro H. S. Pereira, Paula J. Bartlett, Andrew P. Thomas, Katsuhiko Mikoshiba, Helmut Plattner and L. David Sibley








Copper Homeostasis for the Developmental Progression of Intraerythrocytic Malarial Parasite

, 2016; 16(27): 3048 - 3057

Hiroko Asahi, Fumie Kobayashi, Shin-Ichi Inoue, Mamoru Niikura, Kenji Yagita and Mohammed Essa Marghany Tolba




Telomerase as a Cancer Target. Development of New Molecules

, 2016; 16(22): 2432 - 2440

D.L. Mengual Gomez, R.G. Armando, C.S. Cerrudo, P.D. Ghiringhelli and D.E. Gomez





HCN Channels Modulators: The Need for Selectivity

, 2016; 16(16): 1764 - 1791

Maria Novella Romanelli, Laura Sartiani, Alessio Masi, Guido Mannaioni, Dina Manetti, Alessandro Mugelli and Elisabetta Cerbai





Biomarkers in the Management of Difficult Asthma

, 2016; 16(14): 1561 - 1573

Florence Schleich, Sophie Demarche and Renaud Louis







Most Cited Articles







Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

, 2016; 16(14): 1610-1630.

Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi


DOI: 10.2174/1568026616666151223113540


Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

, 2016; 16(5): 485-492.

Yanxing Chen, Jianfang Zhang, Baorong Zhang and Cheng-Xin Gong


DOI: 10.2174/1568026615666150813142423






Most Accessed Articles


Genetic Mechanisms of Antibiotic Resistance and the Role of Antibiotic Adjuvants

, 2018; 18(1): 42-74.

Daniela Santos Pontes, Rodrigo Santos Aquino de Araujo, Natalina Dantas, Luciana Scotti , Marcus Tullius Scotti, Ricardo Olimpio de Moura and Francisco Jaime Bezerra Mendonca-Junior *


DOI: 10.2174/1568026618666180206095224



New Benzothiazole-based Thiazolidinones as Potent Antimicrobial Agents. Design, synthesis and Biological Evaluation

, 2018; 18(1): 75-87.

Michelyne Haroun*, Christophe Tratrat, Katerina Kositzi, Evangelia Tsolaki, Anthi Petrou, Bandar Aldhubiab, Mahesh Attimarad, Sree Harsha, Athina Geronikaki*, Katharigatta N. Venugopala, Heba S. Elsewedy, Marina Sokovic, Jasna Glamoclija and Ana Ciric


DOI: 10.2174/1568026618666180206101814


3D-QSAR in Drug Design - A Review

, 2010; 10(1): 95-115.

Jitender Verma, Vijay M. Khedkar and Evans C. Coutinho


DOI: 10.2174/156802610790232260





Recent Development of Small Molecule Glutaminase Inhibitors

, 2018; 18(6): 432-443.

Minsoo Song*, Soong-Hyun Kim, Chun Young Im and Hee-Jong Hwang


DOI: 10.2174/1568026618666180525100830




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