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Forthcoming Special Issues

Recent in-silico research in high-throughput drug discovery and molecular biochemistry


Guest Editor(s): Jian Zhang, Haiting Chai
Tentative Publication Date: December, 2018
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Published Special Issues

Medicinal Chemistry of Farnesoid X Receptor (FXR) Modulators: The-State-of-the-Art


Guest Editor(s): Maura Marinozzi

Authors' Comments
It has been a great experience publishing my research work with Bentham Science Publishers. The editorial board is very professional. I would highly recommend the journal “Current Topics in Medicinal Chemistry” to my colleagues.

Maité Sylla-Iyarreta Veitía
(Equipe de chimie moléculaire, Laboratoire de Chimie moléculaire, génie des procédés chimiques et énergétiques, EA7341, Conservatoire national des arts et métiers, 2 rue Conté, 75003, Paris, France)


Current Topics in Medicinal Chemistry

,

Volume 18

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Number 3



Editorial   Open Access





Review Article

Genistein as a Potential Anticancer Agent Against Head and Neck Squamous Cell Carcinoma

, 18(3): 174 - 181

Fatima Ardito *, Giovanni Di Gioia, Mario Roberto Pellegrino and Lorenzo Lo Muzio


DOI: 10.2174/1568026618666180116122650






Review Article





Review Article





Review Article

Aurora Kinase Inhibitors in Head and Neck Cancer

, 18(3): 199 - 213

Guangying Qi*, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*


DOI: 10.2174/1568026618666180112163741






Review Article

Searching for New Targets and Treatments in the Battle Against Squamous Cell Carcinoma of the Head and Neck, with Specific Focus on Tumours of the Tongue

, 18(3): 214 - 218

Nicola Sgaramella*, Xiaolian Gu, Linda Boldrup, Philip J Coates, Robin Fahraeus, Luigi Califano, Gianpaolo Tartaro, Giuseppe Colella, Lena Norberg Spaak, Adrian Strom , Torben Wilms , Lorenzo Lo Muzio, Giovanni Dell`Aversana Orabona, Mario Santagata, Lotta Loljung, Riccardo Rossiello, Karin Danielsson, Klas Strindlund , Sandra Lillqvist and Karin Nylander*


DOI: 10.2174/1568026618666180116121624






Review Article





Review Article





Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification


Andre Lacerda Braga Teles, Roseane R. Silva, Michelle Ko, Glaucio Monteiro Ferreira, Samuel da Rocha Pita, Gustavo Henrique Goulart Trossini, Paulo Carvalho and Marcelo Santos Castilho*


View Abstract View on PubMed


First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties


Nestor M. Carballeira*, Christian Morales-Guzman, Ester Alvarez-Benedicto, Zally Torres-Martinez, Yamixa Delgado- Reyes, Kai H. Griebenow, Arthur D. Tinoco, Rosa M. Reguera, Yolanda Perez-Pertejo, Ruben Carbajo-Andres and Rafael Balana-Fouce


View Abstract View on PubMed


Insights into Anti-trypanosomal Agents Based on Synthetic Glycoconjugates


Vanessa Leiria Campo*, Marcelo Fiori Marchiori and Ivone Carvalho


View Abstract View on PubMed


Ubiquitin Proteasome System as a Potential Drug Target for Malaria


Pedro H. Scarpelli Pereira, Chiara Curra and Celia R. S. Garcia*


View Abstract View on PubMed


Validation Cytotoxicity Assay for Lipophilic Substances


Natalia Mencacci Esteves-Pedro, Kenji Sugibayashi, Elissa A. Ostrosky, Marcio Ferrari, Bianca da Silva Sufi, Monica Beatriz Mathor, Paulo Roberto H. Moreno, Felipe R. Lourenco, Vladi Olga Consiglieri, Andre R. Baby and Telma Mary Kaneko*


View Abstract View on PubMed


Alternative Host Models for Testing Anti-Protozoal or Antifungal Compounds and Fungal Infection


Ana Claudia Torrecilhas, Patricia Xander, Karen Spadari Ferreira and Wagner Luiz Batista*


View Abstract View on PubMed


Immunometabolism in the Pathogenesis of Depressive Disorders - Therapeutic Considerations


Dietmar Fuchs*, Simon Geisler, Barbara Sperner-Unterweger and Johanna M. Gostner


View Abstract View on PubMed


The Development of New Small-Molecule Inhibitors Targeting Bacterial Metallo-β-lactamases


Ping Wang, Jing Cheng, Cong-Cong Liu, Kai Tang, Feng Xu, Zhiqiang Yu, Bin Yu and Junbiao Chang*


View Abstract


The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use

, 2016; 16(18): 1976 - 1989

Daniel Iglesias, Susanna Bosi, Michele Melchionna, Tatiana Da Ros and Silvia Marchesan


DOI: 10.2174/1568026616666160215154807



Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease

, 2016; 16(17): 1951 - 1960

Nady Braidy, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Hussein Mansour, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant


DOI: 10.2174/1568026616666160204121431



Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

, 2016; 16(16): 1792 - 1818

Robert A. Pearlstein, K. Andrew MacCannell, Gül Erdemli, Sarita Yeola, Gabriel Helmlinger, Qi-Ying Hu, Ramy Farid, William Egan, Steven Whitebread, Clayton Springer, Jeremy Beck, Hao-Ran Wang, Mateusz Maciejewski, Laszlo Urban and José S. Duca


DOI: 10.2174/1568026616666160315142156



Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

, 2016; 16(14): 1610 - 1630

Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi


DOI: 10.2174/1568026616666151223113540



Current Drug Discovery for Anti-hepatitis C Virus Targeting NS4B

, 2016; 16(12): 1362 - 1371

Zhenya Wang, Xinli Chen, Chunli Wu, Haiwei Xu and Hongmin Liu


DOI: 10.2174/1568026616666151120112642



Bispidine as a Privileged Scaffold

, 2016; 16(11): 1314 - 1342

Isabelle Tomassoli and Daniela Gündisch


DOI: 10.2174/1568026615666150915111434



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