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Current Pharmaceutical Biotechnology

Volume 20, 15 Issues, 2019
ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)
This journal supports open access

Ranking and Category

  • 259th of 298 in

    Biochemistry & Molecular Biology

  • 219th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth/mini reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:

  • DNA/protein engineering and processing
  • Synthetic biotechnology
  • Omics (genomics, proteomics, metabolomics and systems biology)
  • Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
  • Drug delivery and targeting
  • Nanobiotechnology
  • Molecular pharmaceutics and molecular pharmacology
  • Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
  • Pharmacokinetics and pharmacodynamics
  • Applied Microbiology
  • Bioinformatics (computational biopharmaceutics and modeling)
  • Environmental biotechnology
  • Regenerative medicine (stem cells, tissue engineering and biomaterials)
  • Translational immunology (cell therapies, antibody engineering, xenotransplantation)
  • Industrial bioprocesses for drug production and development
  • Biosafety
  • Biotech ethics

Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.

Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Current Pharmaceutical Biotechnology

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Volume 20

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Number 6



Biography   Open Access



Review Article



Research Article



Research Article



Research Article



Research Article

Evaluation of Changes in the Expression Pattern of EDIL3 in Different Grades of Endometrial Cancer

, 20(6): 483 - 488

Marcin Oplawski*, Konrad Dziobek, Nikola Zmarzły, Beniamin Grabarek, Barbara Tomala, Ewa Leśniak, Iwona Adwent, Piotr Januszyk, Dariusz Dąbruś and Dariusz Boroń


DOI: 10.2174/1389201020666190408112822


Research Article

Effect of Pullulan on Physicochemical, Microbiological, and Sensory Quality of Yogurts

, 20(6): 489 - 496

Anna Chlebowska-Śmigiel, Katarzyna Kycia, Katarzyna Neffe-Skocińska, Marek Kieliszek*, Małgorzata Gniewosz and Danuta Kołożyn-Krajewska


DOI: 10.2174/1389201020666190416151129


Research Article



Current Pharmaceutical Biotechnology, Volume 20 (2019) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Biotechnology, Volume 20 (2019) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Natural Products from Mediterranean Diet: From Anti-hyperlipidemic Agents to Dietary Epigenetic Modulators


Georgia-Eirini Deligiannidou, Athina Sygkouna, Berghe Wim Vander, Christos Kontogiorgis* and Theodoros Constantinides


DOI: 10.2174/1573407215666190628150921
View Abstract View on PubMed



Preparation and Characterization of the Biological Compound Effervescent Granule of Calcium Acetate


Zhongbing Liu, Xuemei Sun, Tiantian Liang, Yi Luo, Xiaoyan Chen, Ting Li, Lin Chen, Junjie Wang, Yan Lin, Yun Ye* and Zhirong Zhong


DOI: 10.2174/1389201020666190628144637
View Abstract View on PubMed




Changes in Expression Pattern of SEMA3F Depending on Endometrial Cancer Grade – Pilot Study


Konrad Dziobek*, Marcin Opławski, Beniamin Grabarek, Nikola Zmarzły, Robert Kiełbasiński, Ewa Leśniak, Piotr Januszyk, Krzysztof Januszyk, Iwona Adwent, Dariusz Dąbruś, Przemysław Kieszkowski, Kamil Kiełbasiński, Agnieszka Kuś-Kierach and Dariusz Boroń


DOI: 10.2174/1389201020666190619145655
View Abstract View on PubMed






Abstracts Ahead of Print

Nanoparticles and zeolites: Antibacterial effects and their mechanism against pathogens


Maryam Azizi-lalabadi, Ali Ehsani, Mahmood Alizadeh-Sani, Arezou Khezerlou, Mina Mirzanajafi-Zanjani, Baharak Divband, Hajar Zolfaghari and Vahid Bagheri


DOI: 10.2174/1573397115666190708120040
View Abstract




Changes in the expression profile of VEGF-A, VEGF-B, VEGFR-1, VEGFR-2 in different grades of endometrial cancer


Konrad Dziobek*, Marcin Opławski, Beniamin Grabarek, Nikola Zmarzły, Barbara Tomala, Tomasz Halski, Ewa Leśniak, Krzysztof Januszyk, Ryszard Brus, Robert Kiełbasiński and Dariusz Boroń


DOI: 10.2174/1389201020666190717092448
View Abstract


Plant Phenolics and Lectins as Vaccine Adjuvants


Hernández-Ramos Reyna-Margarita, Castillo-Maldonado Irais, Rivera-Guillén Mario-Alberto, Ramírez-Moreno Agustina, Serrano-Gallardo Luis-Benjamín and Pedroza-Escobar David*


DOI: 10.2174/1389201020666190716110705
View Abstract






Published Contents

Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Editor's Choice

Tuberculosis: Current Status, Diagnosis, Treatment and Development of Novel Vaccines

, 2019; 20(6): 446 - 458

Jyoti Yadav, Sonali Verma, Darshna Chaudhary, Pawan K. Jaiwal and Ranjana Jaiwal*


DOI: 10.2174/1389201020666190430114121



Tanshinone IIA Promotes Macrophage Cholesterol Efflux and Attenuates Atherosclerosis of apoE-/- Mice by Omentin-1/ABCA1 Pathway

, 2019; 20(5): 422 - 432

Yu-lin Tan, Han-xiao Ou, Min Zhang, Duo Gong, Zhen-wang Zhao, Ling-yan Chen, Xiao-dan Xia, Zhong-cheng Mo* and Chao-ke Tang*


DOI: 10.2174/1389201020666190404125213





Downregulation of TdT Expression through Splicing Modulation by Antisense Peptide Nucleic Acid (PNA)

, 2019; 20(2): 168 - 178

Soheila Montazersaheb, Masoumeh Kazemi, Elahe Nabat, Peter E. Nielsen* and Mohammad S. Hejazi*


DOI: 10.2174/1389201020666190206202650




The Role of Extracellular Nucleic Acids in Rheumatoid Arthritis

, 2018; 19(15): 1182 - 1188

Elena Neumann*, Rebecca Hasseli, Uwe Lange and Ulf Müller-Ladner


DOI: 10.2174/1389201020666190102150216






Open Access Articles

Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondrocyte Proliferation or Damage Extracellular Matrix Structures?

, 2019; 20(6): 517 - 524

Necati Kaplan, Ibrahim Yilmaz, Numan Karaarslan*, Yasin E. Kaya, Duygu Y. Sirin and Hanefi Ozbek




Expression of NRP-1 and NRP-2 in Endometrial Cancer

, 2019; 20(3): 254 - 260

Marcin Oplawski*, Konrad Dziobek, Beniamin Grabarek, Nikola Zmarzły, Dariusz Dąbruś, Piotr Januszyk, Ryszard Brus, Barbara Tomala and Dariusz Boroń




Gender Difference Response of Male and Female Immunodeficiency Rats Treated with Tissue-specific Biomolecules

, 2019; 20(3): 245 - 253

Liliya V. Fedulova, Alexandr A. Basov, Ekaterina R. Vasilevskaya and Stepan S. Dzhimak*




Effect of Powdered Activated Carbon as Advanced Step in Wastewater Treatments on Antibiotic Resistant Microorganisms

, 2019; 20(1): 63 - 75

Damiana Ravasi, Roger König, Pamela Principi, Giuseppe Perale and Antonella Demarta*





Expression Profile of Endoglin in Different Grades of Endometrial Cancer

, 2018; 19(12): 990 - 995

Marcin Opławski*, Konrad Dziobek, Iwona Adwent, Dariusz Dąbruś, Beniamin Grabarek, Nikola Zmarzły, Andrzej Plewka and Dariusz Boroń




Enzymatic Hydrolysis of Hyaluronic Layer before Drug Dosing

, 2018; 19(12): 963 - 972

Anna Trusek*, Anita Niesobska and Damian Semba





Development of MTL-CEBPA: Small Activating RNA Drug for Hepatocellular Carcinoma

, 2018; 19(8): 611 - 621

Ryan L. Setten, Helen L. Lightfoot, Nagy A. Habib and John J. Rossi*





Verification between Original and Biosimilar Therapeutic Antibody Infliximab Using nSMOL Coupled LC-MS Bioanalysis in Human Serum

, 2018; 19(6): 495 - 505

Noriko Iwamoto, Kotoko Yokoyama, Megumi Takanashi, Atsushi Yonezawa, Kazuo Matsubara and Takashi Shimada*





Collaboration of the Joint Research Centre and European Customs Laboratories for the Identification of New Psychoactive Substances

, 2018; 19(2): 91 - 98

Claude Guillou*, Fabiano Reniero, Joana Lobo Vicente, Margaret Holland, Kamil Kolar, Hubert Chassaigne, Salvatore Tirendi and Herve Schepers







Most Cited Articles

Review Article

Car T-cell therapy: A new era in cancer immunotherapy

, 2018; 19(1): 5-18.

Miliotou N. Androulla and Papadopoulou C. Lefkothea*


DOI: 10.2174/1389201019666180418095526



Review Article

Analytical approaches in fatal intoxication cases involving new synthetic opioids

, 2018; 19(2): 113-123.

Enrico Gerace*, Alberto Salomone and Marco Vincenti


DOI: 10.2174/1389201019666180405162734


Review Article

Naringenin and its nano-formulations for fatty liver: Cellular modes of action and clinical perspective

, 2018; 19(3): 196-205.

Mehdi Zobeiri, Tarun Belwal, Fatemeh Parvizi, Rozita Naseri, Mohammad H. Farzaei*, Seyed F. Nabavi, Antoni Sureda and Seyed M. Nabavi


DOI: 10.2174/1389201019666180514170122


General Review Article

Recent progress and future perspectives of antibiofilm drugs immobilized on nanomaterials

, 2018; 19(8): 631-643.

Fazlurrahman Khan, Mohammad M. Khan and Young-Mog Kim*


DOI: 10.2174/1389201019666180828090052


General Review Article

Apoptosis: Mediator molecules, interplay with other cell death processes and therapeutic potentials

, 2018; 19(8): 644-663.

Jiban Barman, Ritesh Kumar, Gundappa Saha, Kartikeya Tiwari and Vikash K. Dubey*


DOI: 10.2174/1389201019666180821093239




Research Article

Changes in the expression profile of JAK/STAT signaling pathway genes and mirnas regulating their expression under the adalimumab therapy

, 2018; 19(7): 556-565.

Beniamin Grabarek, Dominika Wcislo-Dziadecka*, Joanna Gola, Celina Kruszniewska-Rajs, Ligia Brzezinska-Wcislo, Nikola Zmarzly and Urszula Mazurek


DOI: 10.2174/1389201019666180730094046


Review Article

Development of MTL-CEBPA: Small activating RNA drug for hepatocellular carcinoma

, 2018; 19(8): 611-621.

Ryan L. Setten, Helen L. Lightfoot, Nagy A. Habib and John J. Rossi*


DOI: 10.2174/1389201019666180611093428



Review Article

Intestinal crosstalk between microbiota and serotonin and its impact on gut motility

, 2018; 19(3): 190-195.

Xiaolong Ge, Junhai Pan, Yichang Liu, Hongkan Wang, Wei Zhou* and Xianfa Wang


DOI: 10.2174/1389201019666180528094202


Review Article

Nigella sativa L. And its bioactive constituents as hepatoprotectant: A review

, 2018; 19(1): 43-67.

Heena Tabassum, Asad Ahmad and Iffat Z. Ahmad*


DOI: 10.2174/1389201019666180427110007



Research Article

Gastroduodenal disorders in patients with CVID undergoing immunoglobulin therapy

, 2018; 19(9): 734-741.

Gilda Varricchi *, Antonio Pecoraro *, Ludovica Crescenzi , Giancarlo Marone , Antonio Travaglino , Francesco Paolo D'Armiento , Arturo Genovese and Giuseppe Spadaro


DOI: 10.2174/1389201019666181010170630



Most Accessed Articles

CAR T-cell Therapy: A New Era in Cancer Immunotherapy

, 2018; 19(1): 5-18.

Androulla N. Miliotou and Lefkothea C. Papadopoulou*


DOI: 10.2174/1389201019666180418095526




HELLP Syndrome: Pathophysiology and Current Therapies

, 2018; 19(10): 816-826.

Kedra Wallace*, Sharonda Harris, Augustina Addison and Cynthia Bean


DOI: 10.2174/1389201019666180712115215


Hyperglycemia and Diabetes Induced by Glucocorticoids in Nondiabetic and Diabetic Patients: Revision of Literature and Personal Considerations

, 2018; 19(15): 1210-1220.

Ceccarelli Elena*, Mattaliano Chiara, Brazzi Angelica, Marinetti A. Chiara, Nigi Laura, Chirico Chiara, Corallo Claudio, Fioravanti Antonella and Giordano Nicola


DOI: 10.2174/1389201020666190102145305








Editor-in-Chief

Davide Prosperi
Department of Biotechnology and Bioscience
University of Milano-Bicocca
Milano
Italy

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Biotechnology was launched in 2000. Dr. Davide Prosperi serves as the Editor-in-Chief of the journal.
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