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Current Molecular Medicine

Volume 19, 10 Issues, 2019
ISSN: 1875-5666 (Online)
ISSN: 1566-5240 (Print)
This journal supports open access

Aims & Scope

Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.

Current Molecular Medicine

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Volume 19

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Number 1



Editorial   Open Access



Review Article



Review Article



Research Article



Research Article



Research Article



Research Article

Glucose Oxidase- and UVA-Induced Changes in the Expression Patterns of Seven De-sumoylation Enzymes (SENPs) Are Associated with Cataract Development

, 19(1): 48 - 53

Jia-Wen Xiang , Yuan Xiao, Yuwen Gan, Huimin Chen, Yunfei Liu, Ling Wang, Qian Nie, Fangyuan Liu, Xiaodong Gong, Jia-Ling Fu, Wen-Jie Qing, Lan Yang, Jie Xie, Zhongwen Luo, Ruili Qi, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190311094313


Research Article

The Prognostic and Clinicopathologic Characteristics of OCT4 and Lung Cancer: A Meta-Analysis

, 19(1): 54 - 75

Hui Li*, Liwen Wang, Shupeng Shi, Yadong Xu, Xuejiao Dai, Hongru Li, Jing Wang, Qiong Zhang, Yonggang Wang, Shuming Sun* and Yanping Li*


DOI: 10.2174/1566524019666190308163315


Current Molecular Medicine, Volume 19 (2019) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



Human Papillomavirus Genome based Detection and Typing: A Holistic Molecular Approach


Abhilasha Gautam, Mallikarjuna Rao Gedda, Madhukar Rai, Shyam Sundar and Jaya Chakravarty*


View Abstract View on PubMed




Revealing the Synergistic Mechanism of Multiple Components in Compound Fengshiding Capsule for Rheumatoid Arthritis Therapeutics by Network Pharmacology


Hong Duan, Ke-feng Zhai, Ghulam Jilany Khan, Jie Zhou, Ting-yan Cao, Yu-qi Wu, Ya-ru Zhou, Wen-gen Cao, Gui-zhen Gao and Ling-ling Shan


View Abstract View on PubMed



Diagnostic Value of MiR-125b as a Potential Biomarker for Stage I Lung Adenocarcinoma Lung Adenocarcinoma


Arife Zeybek*, Necdet Öz, Serdar Kalemci , Tuba Edgünlü, Mehmet Kızıltuğ, Kürşad Tosun, Mustafa Tunç, Leyla Tekin and Mehmet Emin Erdal


View Abstract View on PubMed


Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water


Xiangzi Li, Liangtong Li, Xuanchen Liu, Jiawen Wu, Xiaoyu Sun, Zhilin Li, Yong-Jian Geng, Fulin Liu* and Yujuan Zhou*


View Abstract View on PubMed


Blood Circulating Exosomes Contain Distinguishable Fractions of Free and Cell-Surface-Associated Vesicles


Svetlana Tamkovich*, Oleg Tutanov, Anastasia Efimenko, Alina Grigor’eva, Elena Ryabchikova, Natalia Kirushina, Valentin Vlassov, Vsevolod Tkachuk and Pavel Laktionov


View Abstract View on PubMed


Abstracts Ahead of Print


Inhibition of SOX15 Sensitizes Esophageal Squamous Carcinoma Cells to Paclitaxel


Ming Zhang, Jianying Wang, Tianwei Gao, Xin Chen, Yan Xu, Xiaoting Yu, Xianyang Guo, Rong Zhuang, Ziwei Li, Hongjin Wu* and Juehua Yu*


View Abstract


Serum IL-33 level and IL-33, IL1RL1 gene polymorphisms in asthma and multiple sclerosis patients


Maryam Ahmadi, Farshid Fathi, Saloomeh Fouladi, Fereshteh Alsahebfosul, Mostafa Manian and Nahid Eskandari*


View Abstract


FoxF1 is Required for Ciliogenesis and Distribution of Sonic Hedgehog Signaling Components in Cilium


Lu Huang, Marco Tjakra, Desha Luo, Lin Wen, Daoxi Lei, Jinxuan Wang, Tieying Yin, Xiaojuan Zhang, Junli Huang, Yeqi Wang* and Guixue Wang*


View Abstract


Assessment of the effect of baicalin on duck virus hepatitis


Yun Chen, Fangke Yao, Ke Ming, Jintong Shi, Ling Zeng, Deyun Wang, Yi Wu, Yuanliang Hu and Jiaguo Liu*


View Abstract



Identifying the potential substrates of the depalmitoylation enzyme Acyl-protein thioesterase 1


Huicong Liu, Peipei Yan, Junyan Ren, Can Wu, Wei Yuan, Muding Rao, Zhongjian Zhang* and Eryan Kong*


View Abstract


Editor's Choice


Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis

, 2018; 18(8): 542 - 549

Qian Nie, Ling Wang , Xiaodong Gong, Jia-Wen Xiang, Yuan Xiao, Jie Xie, Lan Yang, Huimin Chen, Yuwen Gan, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190111152324



Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats

, 2018; 18(7): 436 - 447

Rui Zheng, Xiaoliang Fang, Lei He, Yanjiao Shao, Nana Guo, Liren Wang, Mingyao Liu, Dali Li* and Hongquan Geng*


DOI: 10.2174/1566524019666181212092440



Digitoxin Suppresses Store Operated Calcium Entry by Modulating Phosphorylation and the Pore Region of Orai1

, 2018; 18(6): 392 - 399

Lijuan Zhou, Xiangxiang Chi, Yaping Zhu, Tian Zhang, Jindou Liu, Guolin Ma, Lian He, Shuce Zhang, Ping Gao, Yubin Zhou*, Jin Liu* and Youjun Wang


DOI: 10.2174/1566524018666181113111316



Hypoxia-Induced Caveolin-1 Expression Promotes Migration and Invasion of Tumor Cells

, 2018; 18(4): 199 - 206

J. Castillo Bennett, P. Silva, S. Martinez, V.A. Torres* and A.F.G. Quest*


DOI: 10.2174/1566524018666180926163218







Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment

, 2017; 17(10): 668 - 688

N.M. Salkho, R.Z. Turki, O. Guessoum, A.M. Martins, R.F. Vitor and G.A. Husseini*


DOI: 10.2174/1566524018666180416100142



Open Access Articles

Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparα Pathway

, 2018; 18(10): 698 - 710

Zeng Wang, Huairui Shi, Huan Zhao, Zhen Dong, Buchang Zhao, Xinyu Weng, Rongle Liu, Xiao Li, Kai Hu, Yunzeng Zou, Aijun Sun* and Junbo Ge *





Oxidative Stress in Cerebral Small Vessel Disease Dizziness Patients, Basally and After Polyphenol Compound Supplementation

, 2018; 18(3): 160 - 165

L. Ulivi, M. Maccarrone, N. Giannini, E. Ferrari, M.C. Caselli, V. Montano, L. Chico, A. Casani, E. Navari, N. Cerchiai, G. Siciliano, U. Bonuccelli and M. Mancuso*




Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease

, 2018; 18(2): 83 - 90

J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*




ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells

, 2018; 18(2): 109 - 115

W. Liu, W. Yuan, X. Li, J. Zhuang, X. Mo, G. Dai, Y. Wang, J. Chen, Y. Wan, Y. Li, X. Zhu, Y. Chen, S. Luo, Z. Jiang, Y. Shi, F. Chen, L. Cao, X. Ye, X. Fan*, P. Zhu*, K. Zhang* and X. Wu*




Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer

, 2018; 18(2): 100 - 108

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*






Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development

, 2017; 17(9): 627 - 636

F. Chen, W. Yuan, X. Mo, J. Zhuang, Y. Wang, J. Chen, Z. Jiang, X. Zhu, Q. Zeng, Y. Wan, F. Li, Y. Shi, L. Cao, X. Fan, S. Luo, X. Ye, Y. Chen, G. Dai, J. Gao, X. Wang, H. Xie*, P. Zhu*, Y. Li* and X. Wu*




The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila

, 2017; 17(7): 509 - 517

Q. Zeng, Y. Wan, P. Zhu, M. Zhao, F. Jiang, J. Chen, M. Tang, X. Zhu, Y. Li, H. Zha, Y. Wang, M. Hu, X. Mo, Y. Zhang, Y. Chen, Y. Chen, X. Ye, R. Bodmer, K. Ocorr, Z. Jiang*, J. Zhuang*, W. Yuan* and X. Wu*






Proteotoxic Stress Desensitizes TGF-beta Signaling Through Receptor Downregulation in Retinal Pigment Epithelial Cells

, 2017; 17(3): 189 - 199

X. Tan, C. Chen, Y. Zhu, J. Deng, X. Qiu, S. Huang, F. Shang, B. Cheng* and Y. Liu*





Serum miRNAs Signature Plays an Important Role in Keloid Disease

, 2016; 16(5): 504 - 514

Y. Luan, Y. Liu, C. Liu, Q. Lin, F. He, X. Dong and Z. Xiao





Most Cited Articles


DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction

, 2016; 16(1): 91-102.

D. Zou, L. Chen, D. Deng, D. Jiang, F. Dong, C. McSweeney, Y. Zhou, L. Liu, G. Chen, Y. Wu and Y. Mao


DOI: 10.2174/1566524016666151222150024


Modulation of intracellular pH in human ovarian cancer.

, 2016; 16(1): 23-32.

C. Sanhueza, J. Araos, L. Naranjo, R. Villalobos, F. Westermeier, C. Salomon, A.R. Beltrán, M.A. Ramírez, J. Gutiérrez, F. Pardo, A. Leiva and L. Sobrevia


DOI: 10.2174/1566524016666151222143437










Most Accessed Articles

Spinal Muscular Atrophy: More than a Disease of Motor Neurons?

, 2016; 16(9): 779-792.

L. A. Nash, J. K. Burns, J. Warman Chardon, R. Kothary and R. J. Parks


DOI: 10.2174/1566524016666161128113338


VEGFR2 and VEGF-C Suppresses the Epithelial-Mesenchymal Transition Via YAP in Retinal Pigment Epithelial Cells

, 2018; 18(5): 273-286.

Y. Du, Q. Chen, L. Huang, S. Wang, X. Yin, L. Zhou, Z. Ye, X. Ren, Y. Cai, X. Ding, H. Ouyang, X. Li* and R. Ju*


DOI: 10.2174/1566524018666181004115304



Serotonin and Cancer: What Is the Link?

, 2015; 15(1): 62-77.

D. Sarrouilhe, J. Clarhaut, N. Defamie and M. Mesnil


DOI: 10.2174/1566524015666150114113411


Genetic Modifiers of Fetal Haemoglobin (HbF) and Phenotypic Severity in β-Thalassemia Patients

, 2018; 18(5): 295-305.

S.A.A. Razak, N.A.A. Murad*, F. Masra, D.L.S. Chong, N. Abdullah, N. Jalil, H. Alauddin, R.Z.A.R. Sabudin, A. Ithnin, L.C. Khai, N.A. Aziz, Z. Muda, H. Ibrahim and Z.A. Latiff*


DOI: 10.2174/1566524018666181004121604


Establishment of Retinal Degeneration Model in Rat and Monkey by Intravitreal Injection of Sodium Iodate

, 2018; 18(6): 352-364.

Qingjian Ou, Tong Zhu, Peng Li, Zongyi Li, Li Wang, Chunpin Lian, Hua Xu, Caixia Jin, Furong Gao, Jing-Ying Xu, Juan Wang, Jieping Zhang, Weiye Li, Haibin Tian*, Lixia Lu* and Guo-Tong Xu*


DOI: 10.2174/1566524018666181113104023



DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction

, 2016; 16(1): 91-102.

D. Zou, L. Chen, D. Deng, D. Jiang, F. Dong, C. McSweeney, Y. Zhou, L. Liu, G. Chen, Y. Wu and Y. Mao


DOI: 10.2174/1566524016666151222150024



Hypoxia-Induced Caveolin-1 Expression Promotes Migration and Invasion of Tumor Cells

, 2018; 18(4): 199-206.

J. Castillo Bennett, P. Silva, S. Martinez, V.A. Torres* and A.F.G. Quest*


DOI: 10.2174/1566524018666180926163218



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