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Current Medicinal Chemistry

Volume 29, 42 Issues, 2022
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Articles Ahead of Print













Differential Expression of microRNAs in Acute and Chronic Heart Failure


Aimilios Kalampogias*, Evangelos Oikonomou*, Gerasimos Siasos, Panagiotis Theofilis, Stathis Dimitropoulos, Maria Gazouli, Vasiliki Gennimata, Georgios Marinos, Georgios Charalambous, Manolis Vavouranakis, Konstantinos Tsioufis and Dimitris Tousoulis


DOI: 10.2174/0929867329666220426095655
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Dihydrochalcones as Antitumor Agents


Fabiola De Luca, Carla Di Chio, Maria Zappalà and Roberta Ettari*


DOI: 10.2174/0929867329666220415113219
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Translocator Protein 18-kDa: A Promising Target to Treat Neuroinflammation-related Degenerative Diseases


Chiara Tremolanti, Lorenzo Germelli, Elisabetta Barresi, Eleonora Da Pozzo*, Francesca Simorini, Sabrina Castellano, Sabrina Taliani*, Federico Da Settimo, Claudia Martini and Barbara Costa


DOI: 10.2174/0929867329666220415120820
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Chronic Kidney Disease-Mineral Bone Disease Biomarkers in Kidney Transplant Patients


Ursula Gramiscelli Hasparyk, Flávia Maria Borges Vigil, Victória Soares Bartolomei, Vitor Moreira Nunes and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867329666220318105856
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Target Mutation-Driven Drug Discovery


Concetta Altamura*, Diana Conte, Maria Rosaria Carratù and Jean-François Desaphy


DOI: 10.2174/1389450123666220418111200
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Betaine Modulating MIF-mediated Oxidative Stress, Inflammation and Fibrogenesis in Thioacetamide-induced Nephrotoxicity


Bojan Jorgačević, Sanja Stanković, Jelena Filipović, Janko Samardžić, Danijela Vučević and Tatjana Radosavljević*


DOI: 10.2174/0929867329666220408102856
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Potential Application of Cephalosporins Carried in Organic or Inorganic Nanosystems Against Gram-negative Pathogens


Brenda Maria Silva Bezerra, Sara Efigênia Dantas de Mendonça y Araujo, Analara Cordeiro de Macêdo, Kammila Martins Nicolau Costa, Mariana Rillo Sato and João Augusto Oshiro-Junior*


DOI: 10.2174/0929867329666220329201817
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The Role of Mass Spectrometry in the Discovery of Antibiotics and Bacterial Resistance Mechanisms: Proteomics and Metabolomics Approaches


Miguel Cuevas-Cruz, Ulises Hernández-Guzmán, Poulette Carolina Álvarez-Rosales, Meike Schnabel, Saúl Gómez-Manzo and Roberto Arreguín-Espinosa*


DOI: 10.2174/0929867329666220329090822
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Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging


Monica Viviano, Elisabetta Barresi, Fabrice G. Siméon, Barbara Costa, Sabrina Taliani, Federico Da Settimo, Victor W. Pike and Sabrina Castellano*


DOI: 10.2174/0929867329666220329204054
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The ATP-dependent Pathways and Human Diseases


Justyna Suwara, Ewa Radzikowska-Cieciura, Arkadiusz Chworos and Roza Pawlowska*


DOI: 10.2174/0929867329666220322104552
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Exogenous PDE5 Expression Rescues Photoreceptors in RD1 Mice


Tongdan Zou, Ting Wang, Fangyuan Zhen, Xu He, Shuqian Dong and Houbin Zhang*


DOI: 10.2174/0929867329666220216111952
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A2A Adenosine Receptor Antagonists and their Potential in Neurological Disorders


Catia Lambertucci, Gabriella Marucci, Daniela Catarzi, Vittoria Colotta, Beatrice Francucci, Andrea Spinaci, Flavia Varano and Rosaria Volpini*


DOI: 10.2174/0929867329666220218094501
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Casein Kinase 1δ Inhibitors as Promising Therapeutic Agents for Neurodegenerative Disorders


Daniela Catarzi, Flavia Varano, Erica Vigiani, Catia Lambertucci, Andrea Spinaci, Rosaria Volpini and Vittoria Colotta*


DOI: 10.2174/0929867329666220301115124
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Molecular Link between Circadian Rhythmicity and Mood Disorders


Frank Faltraco, Denise Palm, Andrew Coogan, Frederick Simon, Oliver Tucha and Johannes Thome*


DOI: 10.2174/0929867328666211007113725
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Black Phosphorous Aptamer-based Platform for Biomarker Detection


Ajinkya Nene, Shengyong Geng, Wenhua Zhou*, Xue-Feng Yu, Hongrong Luo and Seeram Ramakrishna


DOI: 10.2174/0929867329666220225110302
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Selenium-Derivative Compounds: A Review of New Perspectives in the Treatment of Alzheimer's Disease


Flavio A. R. Barbosa, Rômulo F. S. Canto, Kerolain F. Teixeira, Anacleto Silva de Souza, Aldo S. de Oliveira and Antonio L. Braga*


DOI: 10.2174/0929867329666220224161454
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Comparative Study to Characterise the Pharmaceutical Potential of Synthesised Snake Venom Bradykinin-Potentiating Peptides In Vivo


Aisha Munawar, Fakhar Zaman, Muhammad Waqas Ishaq, Khawaja Ali Hassan, Saima Masood, Zahid Ali, Khalid Abdul Majeed, Ahmed Akrem, Syed Abid Ali and Christian Betzel


DOI: 10.2174/0929867329666220203153051
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Recent Advances in the Selection of Cancer-Specific Aptamers for the Development of Biosensors


Diana A. Sousa, Mariana Carneiro, Débora Ferreira, Felismina T. C. Moreira, Maria Goreti F. Sales and Lígia R. Rodrigues*


DOI: 10.2174/0929867329666220224155037
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Glycogen Synthase Kinase 3β Involvement in Neuroinflammation and Neurodegenerative Diseases


Teresa Gianferrara, Eleonora Cescon, Ilenia Grieco, Giampiero Spalluto and Stephanie Federico*


DOI: 10.2174/0929867329666220216113517
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Selenium-containing Peptides and their Biological Applications


Kainat Ahmed, Delawar Ashraf, Ghayoor Abbas Chotana, Amir Faisal, Khalid Mohammed Khan* and Rahman Shah Zaib Saleem*


DOI: 10.2174/0929867329666220214104010
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Computational Strategies to Identify New Drug Candidates against Neuroinflammation


Matteo Pavan, Davide Bassani, Giovanni Bolcato, Maicol Bissaro, Mattia Sturlese and Stefano Moro*


DOI: 10.2174/0929867329666220208095122
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Aptamer-based Emerging Tools for Viral Biomarker Detection: A Focus on SARS-CoV-2


Prabir Kumar Kulabhusan, Parsa Pishva, Eda Çapkın, Prajakta Tambe and Meral Yüce*


DOI: 10.2174/1568009622666220214101059
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Nanoparticle Mediated Gene Therapy: A Trailblazer Armament to Fight CNS Disorders


Annu, Saleha Rehman, Bushra Nabi, Ali Sartaj, Shadab Md, PK Sahoo, Sanjula Baboota and Javed Ali*


DOI: 10.2174/0929867329666220105122318
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Kinase Inhibitors Involved in the Regulation of Autophagy: Molecular Concepts and Clinical Implications


Isehaq Al-Huseini, Srinivasa Rao Sirasanagandla, Kondaveeti Suresh Babu, Ramakrishna Gopala Sumesh Sofin and Srijit Das*


DOI: 10.2174/0929867329666220117114306
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Polypharmacy- Purpose, Benefits and Limitations


Douglas Grover*, Michelle Tom, Gerald Maguire and Stephen Stahl


DOI: 10.2174/0929867329666220107153813
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A Novel Approach for Designing Electrochemical Aptamer-Based Biosensor for Ultrasensitive Detection of Zearalenone as a Prevalent Estrogenic Mycotoxin


Shokoufeh Hassani*, Armin Salek Maghsoudi, Milad Rezaei Akmal, Shahram Shoeibi, Fatemeh Ghadipasha, Taraneh Mousavi, Mohammad Reza Ganjali, Rohollah Hosseini and Mohammad Abdollahi


DOI: 10.2174/0929867328666211214165814
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2D Materials-Based Aptamer Biosensors: present Status and Way Forward


Raj Kumar Sen, Priyanka Prabhakar, Neha Bisht, Monika Patel, Shruti Mishra, Amit Kumar Yadav, Divya Vadakkumana Venu, Gaurav Kumar Gupta, Pratima R. Solanki, Seeram Ramakrishnan, Dehipada Mondal, Avanish Kumar Srivastava, Neeraj Dwivedi* and Chetna Dhand*


DOI: 10.2174/0929867328666211213115723
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In Search for Biomarkers in Obsessive-Compulsive Disorder: New Evidence on Saliva as a Practical Source of DNA to Assess Epigenetic Regulation


Claudio D’Addario, Monica Macellaro , Fabio Bellia, Beatrice Benatti, Eugenia Annunzi , Riccardo Palumbo, Dario Conti , Federica Fasciana, Matteo Vismara , Alberto Varinelli , Luca Ferrara , Laura Celebre, Caterina Viganò and Bernardo Dell’Osso*


DOI: 10.2174/0929867328666211208115536
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GABA System in Depression: Impact on Pathophysiology and Psychopharmacology


Alessandra Della Vecchia *, Alessandro Arone, Armando Piccinni , Federico Mucci and Donatella Marazziti


DOI: 10.2174/0929867328666211115124149
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Prothymosin α and Its C-Terminal Immunoreactive Decapeptide Show no Evidence of Acute Toxicity: A Preliminary In Silico, In Vitro and In Vivo Investigation


Anastasios I. Birmpilis, Panagiotis Vitsos, Ioannis V. Kostopoulos, Lillian Williams, Kyriaki Ioannou, Pinelopi Samara, Chrysoula-Evangelia Karachaliou, Ioannis F. Voutsas, Elena Alyfanti, Nikolaos Angelis, Nikolaos G. Gavalas, Themis Gkraikou, Niki Kappa, Eleftheria Klagkou, Persefoni Klimentzou, Spiridoula Nikou, Nikos E. Papaioannou, Margarita Skopeliti, David Toukli, Meletios-Athanasios Dimopoulos, Aristotelis Bamias, Evangelia Livaniou, Hubert Kalbacher, Ourania E. Tsitsilonis* and Wolfgang Voelter


DOI: 10.2174/0929867328666211117093401
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Recent Trends in Rationally Designed Molecules as Kinase Inhibitors


Parteek Prasher, Mousmee Sharma, Yinghan Chan, Sachin Kumar Singh, Krishnan Anand, Harish Dureja, Niraj Kumar Jha, Gaurav Gupta, Flavia Zacconi, Dinesh K. Chellappan and Kamal Dua*


DOI: 10.2174/0929867328666211111161811
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Neutrophil/Lymphocyte, Platelet/Lymphocyte, and Monocyte/Lymphocyte Ratios in Mood Disorders


Donatella Marazziti *, Samuele Torrigiani, Manuel G. Carbone, Federico Mucci , Walter Flamini , Tea Ivaldi and Liliana Dell' Osso


DOI: 10.2174/0929867328666210922160116
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Inflammation, Oxidative Stress, Vascular Aging and Atherosclerotic Ischemic Stroke


Ioannis K. Koutsaliaris, Iraklis C. Moschonas, Louisa M. Pechlivani, Aikaterini N. Tsouka and Alexandros D. Tselepis*


DOI: 10.2174/0929867328666210921161711
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Different Sides of Depression in the Elderly: An In-depth View on the Role of Aβ Peptides Peptides


Giovanni Pagni*, Claudia Tagliarini, Manuel Glauco Carbone, Bruno Pietro Imbimbo, Donatella Marazziti and Nunzio Pomara


DOI: 10.2174/0929867328666210921164816
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Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review


Leila Gholami, Jalil Rouhani Ivari, Niloofar Khandan Nasab, Reza Kazemi Oskuee, Thozhukat Sathyapalan* and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210810160901
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Editor-in-Chief

Atta-ur-Rahman, FRS
(31099 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
View Full Editorial Board

Nobel Laureates on Editorial Board

Prof. John Gurdon
(UK)

Prof. Jean-Marie Lehn
(France)

Prof. Ferid Murad
(USA)

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