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Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

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  • 91st of 298 in

    Biochemistry & Molecular Biology

  • 12th of 61 in

    Chemistry, Medicinal

  • 55th of 267 in

    Pharmacology & Pharmacy

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Articles Ahead of Print

Drug Leads Derived from Japanese Marine Organisms


Daisuke Uemura*, Yoshinori Kawazoe, Toshiyasu Inuzuka, Yuki Itakura, Chiari Kawamata and Takahiro Abe*


DOI: 10.2174/0929867326666191022125851
View Abstract View on PubMed


Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids


Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo


DOI: 10.2174/0929867326666191029112626
View Abstract View on PubMed


In Silico Drug Repositioning for Chagas Disease


Carolina L. Bellera, Lucas N. Alberca, María L. Sbaraglini and Alan Talevi*


DOI: 10.2174/0929867326666191016114839
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The Beneficial Actions of SGLT-2 Inhibitors Beyond the Management of Hyperglycemia


Charalampos Loutradis, Eirini Papadopoulou, Elena Angeloudi, Asterios Karagiannis and Pantelis Sarafidis*


DOI: 10.2174/0929867326666191029111713
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Joint Application of Magnetic Resonance Imaging and Biochemical Biomarkers in Diagnosis of Multiple Sclerosis


Fatemeh Momeni, Amir Ghaemmaghami, Majid Nejati, Mohammad Hossein Pourhanifeh, Laleh Shiri Sichani, Omid Reza Tamtaji, Mohammad Momeni, Alireza Khosravi*, Masoud Etemadifar* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191014162713
View Abstract View on PubMed



Coronary Artery Disease and Endothelial Dysfunction: Novel Diagnostic and Therapeutic Approaches


Evangelos Oikonomou*, Gerasimos Siasos, Vasiliki Tsigkou, Evanthia Bletsa, Maria-Evi Panoilia, Iris Niovi Oikonomou, Ilias Sinanidis, Marianna Spinou, Angeliki Papastavrou, Georgios Kokosias, Marina Zaromitidou, Panagiota Stampouloglou, Michael Spartalis, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitris Tousoulis


DOI: 10.2174/0929867326666190830103219
View Abstract View on PubMed



Recent Theoretical Studies Concerning Important Tropical Infections


Alex France Messias Monteiro, Jessika de Oliveira Viana*, Francisco Jaime BM Junior, Hamiilton M Ishiki, Ernestine Nkwengoua Tchouboun, Rodrigo Santos de Araújo, Marcus Tullius Scotti and Luciana Scotti


DOI: 10.2174/0929867326666190711121418
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Anti-VEGF Treatment and Response in Age-related Macular Degeneration: Disease´s Susceptibility, Pharmacogenetics and Pharmacokinetics


Olalla Maroñas , Laura García-Quintanilla*, Andrea Luaces-Rodríguez, Anxo Fernández-Ferreiro, Ana Latorre-Pellicer, Maximino José Abraldes, María Jesús Lamas and Ángel Carracedo *


DOI: 10.2174/0929867326666190711105325
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QSAR by Minimal Topological Difference[s]. Post-Modern Perspectives


Corina Duda-Seiman, Daniel Duda-Seiman, Dan Ciubotariu and Mihai Viorel Putz*


DOI: 10.2174/0929867326666190704124857
View Abstract View on PubMed










Stem Cell Transplant for Advanced Stage Liver Disorders: Current Scenario and Future Prospects


Anjum Mahmood, Rajasekar Seetharaman, Prashant Kshatriya, Divyang Patel and Anand S. Srivastava*


DOI: 10.2174/0929867326666191004161802
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The Role of the Endothelium in Premature Atherosclerosis: Molecular Mechanisms


Michael Spartalis*, Eleftherios Spartalis, Antonios Athanasiou, Stavroula A Paschou, Christos Kontogiannis, Georgios Georgiopoulos, Dimitrios C Iliopoulos and Vassilis Voudris


DOI: 10.2174/0929867326666190911141951
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Molecular Markers of Regulatory T Cells in Cancer Immunotherapy with Special Focus on Acute Myeloid Leukemia (AML) - A Systematic Review


Parham Jabbarzadeh Kaboli, Lingling Zhang, Shixin Xiang, Jing Shen, Mingxing Li, Yueshui Zhao, Xu Wu, Qijie Zhao, Hanyu Zhang, Ling Lin, Jianhua Yin, Yuanlin Wu, Lin Wan, Tao Yi, Xiang Li, Chi Hin Cho, Jing Li*, Zhangang Xiao* and Qinglian Wen


DOI: 10.2174/0929867326666191004164041
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Discovery and Development of the Oral Complement Factor D Inhibitor ACH-4471


Jason A. Wiles, Manuel D. Galvan, Steven D. Podos, Michael Geffner and Mingjun Huang*


DOI: 10.2174/0929867326666191001130342
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Small Molecules with Anti Prion Activity


Carlo Mustazza*, Marco Sbriccoli, Paola Minosi and Carla Raggia


DOI: 10.2174/0929867326666190927121744
View Abstract View on PubMed


Role of microRNAs in Chronic Lymphocytic Leukemia Pathogenesis


Ehsan Javandoost, Ehsan Firoozi Majd, Hosein Rostamian, Mohammad Khakpoor Koosheh and Hamid Reza Mirzaei*


DOI: 10.2174/0929867326666190911114842
View Abstract View on PubMed


Recent Progress of Benzimidazole Hybrids for Anticancer Potential


Md Jawaid Akhtar, M. Shahar Yar*, V. K. Sharma, Ahsan Ahmed Khan, Zulphikar Ali, Md Rafi Haider and Ankita Pathak


DOI: 10.2174/0929867326666190808122929
View Abstract View on PubMed



The Potential of Frog Skin Peptides for Anti-Infective Therapies: The Case of Esculentin-1a(1-21)NH2


Bruno Casciaro*, Floriana Cappiello, Maria Rosa Loffredo, Francesca Ghirga and Maria Luisa Mangoni


DOI: 10.2174/0929867326666190722095408
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Secondary Metabolites from Deep-sea Derived Microorganisms


Chunxiao Sun, Shah Mudassir, Zhenzhen Zhang, Yanyan Feng, Yimin Chang, Qian Che, Qianqun Gu, Tianjiao Zhu, Guojian Zhang* and Dehai Li*


DOI: 10.2174/0929867326666190618153950
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Mercury Exposure, Epigenetic Alterations, and Brain Tumorigenesis: A Possible Relationship?


Geir Bjørklund*, Lyudmila Pivina, Maryam Dadar, Yuliya Semenova, Salvatore Chirumbolo and Jan Aaseth


DOI: 10.2174/0929867326666190930150159
View Abstract View on PubMed




Role of Exosomes in Photodynamic Anticancer Therapy


Yuan Jiang, Chuanshan Xu*, Wingnang Leung*, Mei Lin, Xiaowen Cai, Huanhuan Guo, Jiyong Zhang and Fanwen Yang


DOI: 10.2174/0929867326666190918122221
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Copper Concentrations in Breast Cancer: A Systematic Review and Meta-Analysis


Leila Jouybari, Faezeh Kiani, Farhad Islami, Akram Sanagoo*, Fatemeh Sayehmiri, Bozena Hosnedlova, Monica Daniela Doşa, Rene Kizek, Salvatore Chirumbolo and Geir Bjørklund*


DOI: 10.2174/0929867326666190918120209
View Abstract View on PubMed




Translational Theragnostic of Ovarian Cancer: where do we stand?


Maria Grazia Perrone, Oreste Luisi, Anna De Grassi, Savina Ferorelli, Gennaro Cormio and Antonio Scilimati*


DOI: 10.2174/0929867326666190816232330
View Abstract View on PubMed


Chemical Mediators’ Expression Associated with the Modulation of Pain in Rheumatoid Arthritis


Cortes-Altamirano J. L., Morraz-Varela A., Reyes-Long S., Gutierrez M., Cindy Bandala, Clavijo-Cornejo D. and Alfaro-Rodriguez A.*


DOI: 10.2174/0929867326666190816225348
View Abstract View on PubMed


Lactoferrin in Bone Tissue Regeneration


Madalina Icriverzi, Valentina Dinca, Magdalena Moisei, Robert W Evans, Mihaela Trif and Anca Roseanu*


DOI: 10.2174/0929867326666190503121546
View Abstract View on PubMed





The Role of Zinc and Copper in Insulin Resistance and Diabetes Mellitus


Geir Bjørklund*, Maryam Dadar, Lyudmila Pivina, Monica Daniela Doşa, Yuliya Semenova and Jan Aaseth


DOI: 10.2174/0929867326666190902122155
View Abstract View on PubMed




The Disposal of Reactive Carbonyl Species through Carnosine Conjugation. What We Know Now


Ettore Gilardoni, Giovanna Baron, Alessandra Altomare, Marina Carini, Giancarlo Aldini and Luca Regazzoni*


DOI: 10.2174/0929867326666190624094813
View Abstract View on PubMed




Metastatic Colorectal Cancer: Prognostic and Predictive Factors


Anna Nappi*, Guglielmo Nasti, Carmela Romano, Massimiliano Berretta and Alessandro Ottaiano


DOI: 10.2174/0929867326666190620110732
View Abstract View on PubMed



VSPrep: A KNIME Workflow for the Preparation of Molecular Databases for Virtual Screening


José-Manuel Gally, Stéphane Bourg, Jade Fogha, Quoc-Tuan Do, Samia Aci-Sèche and Pascal Bonnet


DOI: 10.2174/0929867326666190614160451
View Abstract View on PubMed


Radiochemistry: A Useful Tool in the Ophthalmic Drug Discovery


Krishna Reddy Pulagam, Vanessa Gómez-Vallejo, Jordi Llop* and Luka Rejc*


DOI: 10.2174/0929867326666190530122032
View Abstract View on PubMed




Trojan Microparticles Potential for Ophthalmic Drug Delivery


Sergio Esteban-Pérez, Irene Bravo-Osuna*, Vanessa Andrés-Guerrero, Irene T. Molina-Martínez and Rocío Herrero-Vanrell


DOI: 10.2174/0929867326666190905150331
View Abstract View on PubMed


The Structures and Bioactivities of Fatty Acid Synthase Inhibitors


Hezhong Jiang , Tian Gan , Jiasui Zhang , Qingyun Ma , Yan Liang* and Youxing Zhao*


DOI: 10.2174/0929867326666190507105022
View Abstract


Redox Regulation in the Base Excision Repair Pathway: Old and New Players as Cancer Therapeutic Targets


Aleksandra Rajapakse, Amila Suraweera, Didier Boucher, Ali Naqi, Kenneth O'Byrne, Derek John Richard and Laura Vanda Croft*


DOI: 10.2174/0929867326666190430092732
View Abstract View on PubMed



Circulating Biomarkers for Response Prediction of Rectal Cancer to Neoadjuvant Chemoradiotherapy


Chiara Bedin*, Sara Crotti, Edoardo D`Angelo, Sara D`Aronco, Salvatore Pucciarelli and Marco Agostini


DOI: 10.2174/0929867326666190507084839
View Abstract View on PubMed



Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets


Melisa Sayé, Chantal Reigada, Lucrecia Gauna, Edward A. Valera-Vera, Claudio A. Pereira* and Mariana R. Miranda


DOI: 10.2174/0929867326666190620094710
View Abstract View on PubMed



Endothelial Dysfunction in Dyslipidaemia: Molecular Mechanisms and Clinical Implications


Bozidarka Zaric, Milan Obradovic, Andreja Trpkovic, Maciej Banach, Dimitri P. Mikhailidis and Esma Isenovic*


DOI: 10.2174/0929867326666190903112146
View Abstract View on PubMed


Hybrid Imidazole-Pyridine Derivatives: An Approach to Novel Anticancer DNA Intercalators


Claudiu N. Lungu*, Bogdan Ionel Bratanovici , Grigore Maria Mirabela , Vasilichia Antoci and Ionel I. Mangalagiu*


DOI: 10.2174/0929867326666181220094229
View Abstract View on PubMed


Cardiovascular Effects of Flavonoids


Manuel Sanchez, Miguel Romero, Manuel Gómez-Guzman, Juan Tamargo, Francisco Pérez-Vizcaino and Juan Duarte*


DOI: 10.2174/0929867326666181220094721
View Abstract View on PubMed







Parthenolide and Its Analogues: A New Potential Strategy for the Treatment of Triple-Negative Breast Tumors


Thaise Gonçalves Araújo*, Lara Vecchi, Paula Marynella Alves Pereira Lima, Everton Allan Ferreira, Igor Moreira Campos, Douglas Cardoso Brandão, Gabriela Silva Guimarães, Matheus Alves Ribeiro and Ademar Alves da Silva Filho


DOI: 10.2174/0929867326666190816230121
View Abstract View on PubMed


Graphene and Graphene-Based Materials in Biomedical Applications


Mohammad Omaish Ansari, Kalamegam Gauthaman, Abdurahman Eissa, Sidi A. Bencherif and Adnan Memic*


DOI: 10.2174/0929867326666190705155854
View Abstract View on PubMed


Oxazole-Based Compounds As Anticancer Agents


Maria A. Chiacchio*, Giuseppe Lanza, Ugo Chiacchio, Salvatore V. Giofrè, Roberto Romeo, Daniela Iannazzo and Laura Legnani


DOI: 10.2174/0929867326666181203130402
View Abstract View on PubMed



Advances in Carbon Based Nanomaterials for Bio-Medical Applications


Tejendra Kumar Gupta, Pattabhi Ramaiah Budarapu*, Sivakumar Reddy Chappidi, Sudhir YB Sastry, Marco Paggi and Stephane PA Bordas


DOI: 10.2174/0929867326666181126113605
View Abstract View on PubMed


Pharmaceutical Mixtures: Still A Concern for Human and Environmental Health


Georgeta M. Simu, Jeanne Atchana , Codruta M. Soica, Dorina E. Coricovac, Sebastian C. Simu and Cristina A. Dehelean*


DOI: 10.2174/0929867325666181108094222
View Abstract View on PubMed


Polyoxometalates in Biomedicine: Update and Overview


Mirjana Čolović, Milan Lacković, Jovana Lalatović, Ali S. Mougharbel, Ulrich Kortz* and Danijela Z. Krstić


DOI: 10.2174/0929867326666190827153532
View Abstract View on PubMed


Inflammation as the Common Biological Link Between Depression and Cardiovascular Diseases: Can Carnosine Exert a Protective Role?


Giuseppe Caruso*, Claudia G. Fresta, Margherita Grasso, Rosa Santangelo, Giuseppe Lazzarino, Susan M. Lunte and Filippo Caraci


DOI: 10.2174/0929867326666190712091515
View Abstract View on PubMed



The Structural Details of Aspirin Molecules and Crystals


Ana Maria Toader, Snezana D. Zaric, Christina M. Zalaru and Marilena Ferbinteanu*


DOI: 10.2174/0929867325666181031132823
View Abstract View on PubMed


Current Development of Metal Complexes with Diamine Ligands as Potential Anticancer Agents


Sonja Misirlic-Dencic, Jelena Poljarevic, Andjelka M. Isakovic, Tibor Sabo, Ivanka Markovic and Vladimir Trajkovic*


DOI: 10.2174/0929867325666181031114306
View Abstract View on PubMed


Aim for the Readers! Bromodomains As New Targets Against Chagas’ Disease


Victoria Lucia Alonso, Luis Emilio Tavernelli, Alejandro Pezza, Pamela Cribb, Carla Ritagliati and Esteban Serra*


DOI: 10.2174/0929867325666181031132007
View Abstract View on PubMed


Natural Compounds Therapeutic Features in Brain Disorders by Experimental, Bioinformatics and Cheminformatics Methods


Speranta Avram, Alin Puia, Ana Maria Udrea, Dan Mihailescu, Maria Mernea*, Anca Dinischiotu, Florin Oancea and Johan Stiens


DOI: 10.2174/0929867325666181031123127
View Abstract View on PubMed



The Design and Application of Nanomaterials as Drug Carriers in Cancer Treatment


Jia Hou, Xiaoyan Sun, Ying Huang, Shaohua Yang, Junjie Liu, Changhao Feng, Jun Ma and Bin Chen*


DOI: 10.2174/0929867326666190816231409
View Abstract View on PubMed







Metal Complexes As Promising Agents for Biomedical Applications


Natalia V. Loginova*, Hleb I. Harbatsevich, Nikolai P. Osipovich, Galina A. Ksendzova, Tatsiana V. Koval’chuk and Genrikh I. Polozov


DOI: 10.2174/0929867326666190417143533
View Abstract View on PubMed



In Vitro Immunodetection of Prothymosin Alpha in Normal and Pathological Conditions


Chrysoula-Evangelia Karachaliou, Hubert Kalbacher, Wolfgang Voelter, Ourania E. Tsitsilonis and Evangelia Livaniou*


DOI: 10.2174/0929867326666190807145212
View Abstract View on PubMed



Harmonious Biomaterials for Development of In situ Approaches for Locoregional Delivery of Anti-cancer Drugs: Current Trends


Amrinder Singh, Shubham Thakur, Tushit Sharma, Manjot Kaur, Nikhil Shri Sahajpal, Rohan Aurora and Subheet Kumar Jain*


DOI: 10.2174/1573406415666190621095726
View Abstract View on PubMed





Formulating SLN and NLC as Innovative Drug Delivery Systems for Non-Invasive Routes of Drug Administration


Bruno Fonseca-Santos, Patrícia Bento Silva, Roberta Balasin Rigon, Mariana Rillo Sato and Marlus Chorilli*


DOI: 10.2174/0929867326666190624155938
View Abstract View on PubMed




Immunotherapy for Uveal Melanoma - Current Knowledge and Perspectives


Snježana Kaštelan*, Antonela Gverović Antunica, Lidija Beketić Oresković, Goran Pelčić, Ema Kasun and Koraljka Hat


DOI: 10.2174/0929867326666190704141444
View Abstract View on PubMed


Microbiota, Immune System and Autism Spectrum Disorders. An Integrative Model towards Novel Treatment Options


Barbara Carpita, Donatella Marazziti*, Lionella Palego, Gino Giannaccini, Laura Betti and Liliana Dell'Osso


DOI: 10.2174/0929867326666190328151539
View Abstract










Discovery of Dengue Virus Inhibitors


Adib Afandi Abdullah, Yean Kee Lee, Sek Peng Chin, See Khai Lim, Vannajan Lee, Rozana Othman, Shatrah Othman, Noorsaadah Abdul Rahman, Rohana Yusof and Choon Han Heh*


DOI: 10.2174/0929867326666181204155336
View Abstract View on PubMed


Tuberculosis - Present Medication and Therapeutic Prospects


Anna Jeliñsk, Marianna Zając, Adrianna Dadej, Szymon Tomczak, Małgorzata Geszke-Moritz and Izabela Muszalska*


DOI: 10.2174/0929867325666181120100025
View Abstract View on PubMed




Pharmacological Advances in the Treatment of Age-related Macular Degeneration


María Gil-Martínez*, Paz Santos-Ramos, Maribel Fernández-Rodríguez M, Maximino J Abraldes, Maria José Rodríguez-Cid, María Santiago-Varela, Anxo Fernández-Ferreiro* and Francisco Gómez-Ulla de Irazazábal*


DOI: 10.2174/0929867326666190726121711
View Abstract View on PubMed



Immune-Based Therapies for Traumatic Brain Injury: Insights from Pre-Clinical Studies


Caroline Amaral Machado, Ana Cristina Simões e Silva*, Amanda Silva de Miranda, Thiago Macedo e Cordeiro, Rodrigo Novaes Ferreira, Leonardo Cruz de Souza, Antônio Lúcio Teixeira and Aline Silva de Miranda


DOI: 10.2174/0929867326666190710173234
View Abstract View on PubMed




Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors


Xiao Lv, Yongbing Tian, Shiyu Li, Kai Cheng, Xufeng Huang, Haiyan Kong, Chenzhong Liao and Zhouling Xie*


DOI: 10.2174/0929867326666190402110528
View Abstract View on PubMed


Technological Advances in Preclinical Drug Evaluation: The Role of – Omics Methods


Sandra Kraljević Pavelić*, Elitza Markova-Car, Marko Klobučar, Lana Sappe and Radan Spaventi


DOI: 10.2174/0929867326666190711122819
View Abstract View on PubMed



Repositioning of HIV Aspartyl Peptidase Inhibitors for Combating the Neglected Human Pathogen Trypanosoma cruzi


Leandro Sangenito, Rubem Menna-Barreto, Claudia d`Avila-Levy, Marta Branquinha and André Luis Souza Dos Santos*


DOI: 10.2174/0929867326666190610152934
View Abstract View on PubMed




Insights on Nutrients as Analgesics in Chronic Pain


Geir Bjørklund*, Salvatore Chirumbolo, Maryam Dadar, Joeri J. Pen, Monica Daniela Doşa, Lyudmila Pivina, Yulia Semenova and Jan Aaseth


DOI: 10.2174/0929867326666190712172015
View Abstract View on PubMed


Histone Deacetylases (HDACs) in Gastric Cancer: An Update of Their Emerging Prognostic and Therapeutic Role


Dimitrios Schizas, Aikaterini Mastoraki, Leon Naar, Diamantis I Tsilimigras*, Ioannis Katsaros, Vasiliki Fragkiadaki, Georgia-Sofia Karachaliou, Nikolaos Arkadopoulos, Theodore Liakakos and Dimitrios Moris


DOI: 10.2174/0929867326666190712160842
View Abstract View on PubMed


Targeting Mitochondria Through the Use of Mitocans as Emerging Anticancer Agents


Ioana Macasoi, Alexandra Mioc*, Marius Mioc*, Irina Soica, Adelina Chevereșan, Cristina Dehelean and Victor Dumitrașcu


DOI: 10.2174/0929867326666190712150638
View Abstract View on PubMed





Recent Development on Anti-Obesity Compounds and their Mechanisms of Action: A Review


Yixing Qiu, Huanghe Yu , Rong Zeng, Shiyin Guo, Muhammad Daniyal, Zeyu Deng, Aibing Wang and Wei Wang*


DOI: 10.2174/0929867326666190215114359
View Abstract View on PubMed


Biomarkers, Biosensors and Biomedicine


Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho and Maria Tereza dos Santos Correia*


DOI: 10.2174/0929867326666190124103125
View Abstract View on PubMed


Recent Advances in Spontaneous Raman Spectroscopic Imaging: Instrumentation and Applications


Nan Wang, Honghao Cao, Lin Wang, Feng Ren, Qi Zeng, Xinyi Xu, Jimin Liang, Yonghua Zhan and Xueli Chen*


DOI: 10.2174/0929867326666190619114431
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Protein Microarrays: Valuable Tools for Ocular Diseases Research


María Garranzo-Asensio, Ana Montero-Calle, Guillermo Solís-Fernández, Rodrigo Barderas and Ana Guzman-Aranguez*


DOI: 10.2174/0929867326666190627131300
View Abstract View on PubMed


Autoimmune Hepatitis and Stellate Cells; an Insight into the Role of Autophagy


Shahram Golbabapour, Kamran Bagheri-Lankarani, Saeid Ghavami and Bita Geramizadeh*


DOI: 10.2174/0929867326666190402120231
View Abstract View on PubMed






Differential Characteristics of HMGB2 Versus HMGB1 and their Perspectives in Ovary and Prostate Cancer


María Cámara-Quílez, Aida Barreiro-Alonso, Esther Rodríguez-Bemonte, María Quindós-Varela, Esperanza Cerdán and Mónica Lamas-Maceiras*


DOI: 10.2174/0929867326666190123120338
View Abstract View on PubMed








Targeting Neuropathic Pain: Pathobiology, Current Treatment and Peptidomimetics as a New Therapeutic Opportunity


Maria Cristina Caroleo, Antonella Brizzi*, Maria De Rosa, Ankur Pandey, Luca Gallelli, Mariateresa Badolato, Gabriele Carullo and Erika Cione


DOI: 10.2174/0929867326666190530121133
View Abstract View on PubMed





Obesity and Cardioprotection


Saveria Femminò, Pasquale Pagliaro and Claudia Penna*


DOI: 10.2174/0929867326666190325094453
View Abstract View on PubMed




Anthocyanins As Modulators of Cell Redox-Dependent Pathways in Non-Communicable Diseases


Antonio Speciale, Antonella Saija, Romina Bashllari, Maria Sofia Molonia, Claudia Muscara, Cristina Occhiuto, Francesco Cimino* and Mariateresa Cristani


DOI: 10.2174/0929867325666181112093336
View Abstract View on PubMed




Targeting Tumour Metastasis: The Emerging Role of Nanotechnology


Sarah Visentin, Mirela Sedić, Sandra Kraljević Pavelić and Krešimir Pavelić*


DOI: 10.2174/0929867326666181220095343
View Abstract View on PubMed



B7-H3 Immune Checkpoint Protein in Human Cancer


Karine Flem-Karlsen, Oystein Fodstad and Caroline E. Nunes-Xavier*


DOI: 10.2174/0929867326666190517115515
View Abstract View on PubMed



Reversine: A Synthetic Purine with a Dual Activity as a Cell Dedifferentiating Agent and a Selective Anticancer Drug


Marco Piccoli, Andrea Ghiroldi, Michelle M. Monasky, Federica Cirillo, Giuseppe Ciconte, Carlo Pappone and Luigi Anastasia*


DOI: 10.2174/0929867326666190103120725
View Abstract View on PubMed


Structure and Function of L,D- and D,D-transpeptidase Family Enzymes from Mycobacterium tuberculosis


Gideon F. Tolufashe, Victor T. Sabe, Colins U. Ibeji, Thandokuhle Ntombela, Thavendran Govender, Glenn E. M. Maguire, Hendrik G. Kruger, Gyanu Lamichhane and Bahareh Honarparvar*


DOI: 10.2174/0929867326666181203150231
View Abstract View on PubMed



Quaternized Chitosan Nanoparticles in Vaccine Applications


Shuang Yu , Shengnan Hao, Beini Sun , Dongying Zhao , Xingye Yan and Kai Zhao*


DOI: 10.2174/0929867326666190227192527
View Abstract View on PubMed



Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes


José M. Matés*, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Juan A. Segura, Francisco J. Alonso and Javier Márquez


DOI: 10.2174/0929867326666190416165004
View Abstract View on PubMed


Tear Inflammatory Molecules in Contact Lens Wearers: A Literature Review


Alberto López-dela Rosa, María J González-García, Margarita Calonge* and Amalia Enríquez-de-Salamanca


DOI: 10.2174/0929867326666190409152921
View Abstract View on PubMed




Recent Advances of Chitosan and Its Derivatives in Biomedical Applications


Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao and Yongmin Zhang*


DOI: 10.2174/0929867326666190405151538
View Abstract View on PubMed



Therapeutic applications of Peptides Against Zika Virus: A Review


Preeti Karwal, Ishwar Dutt Vats, Niharika Sinha, Anchal Singhal, Teena Sehgal and Pratibha Kumari*


DOI: 10.2174/0929867326666190111115132
View Abstract View on PubMed


Obesity and Body Composition in Man and Woman: Associated Diseases and the New Role of Gut Microbiota


Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Laura Di Renzo and Antonino De Lorenzo


DOI: 10.2174/0929867326666190326113607
View Abstract View on PubMed


Novel Vaccine Candidates against Tuberculosis


Zhihao Li, Changping Zheng, Marco Terreni, Lisa Tanzi, Matthieu Sollogoub and Yongmin Zhang*


DOI: 10.2174/0929867326666181126112124
View Abstract View on PubMed



A Walk in Nature. Sesquiterpene Lactones as Multi-Target Agents Involved in Inflammatory Pathways


Adriana Coricello, James David Adams*, Eric Lien, Christopher Nguyen, Filomena Perri, Travis J. Williams and Francesca Aiello


DOI: 10.2174/0929867325666180719111123
View Abstract View on PubMed


Targeting n-3 Polyunsaturated Fatty Acids in Non-alcoholic Fatty Liver Disease


Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis A. Videla


DOI: 10.2174/0929867326666190410121716
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Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus


Qingjun Pan*, Yun Guo*, Linjie Guo*, Shuzhen Liao, Chunfei Zhao, Sijie Wang and Hua-feng Liu


DOI: 10.2174/0929867326666190404140658
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From Recognition to Reaction Mechanism: An Overview on the Interactions between HIV-1 Protease and its Natural Targets


Monsurat M. Lawal, Zainab K. Sanusi, Thavendran Govender, Glenn E. M. Maguire, Bahareh Honarparvar and Hendrik G. Kruger*


DOI: 10.2174/0929867325666181113122900
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Structural Basis of Drug Recognition by Human Serum Albumin


Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi


DOI: 10.2174/0929867326666190320105316
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Anesthetic-induced Myocardial Conditioning: Molecular Fundamentals and Scope


Jose Luis Guerrero Orriach*, Juan Jose Escalona Belmonte , Marta Ramirez-Aliaga, Alicia Ramirez-Fernandez , Aida Raigon-Ponferrada , Manuel Rubio-Navarro and Jose Cruz-Manas


DOI: 10.2174/0929867325666180926161427
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B7-H3-targeted Radioimmunotherapy of Human Cancer


Benjamin B. Kasten, Soldano Ferrone, Kurt R. Zinn and Donald J. Buchsbaum*


DOI: 10.2174/0929867326666190228120908
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Metabolomic Biomarkers in Gynecology: A Treasure Path or a False Path?


Igor Govorov , Stanislav Sitkin , Tatyana Pervunina , Alexey Moskvin , Denis Baranenko and Eduard Komlichenko


DOI: 10.2174/0929867326666190104124245
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Onion-Like Carbon Nanostructures: An Overview of Bio-Applications


Diana M. Bobrowska, Piotr Olejnika, Luis Echegoyen and Marta E. Plonska-Brzezinska*


DOI: 10.2174/0929867325666181101105535
View Abstract View on PubMed




Obesity Therapy: How and Why?


S. Paccosi, B. Cresci, L. Pala, C. M. Rotella and A. Parenti*


DOI: 10.2174/0929867326666190124121725
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Exosome-like Nanoparticles: A New Type of Nanocarrier


Mário Fernandes, Ivo Lopes, José Teixeira, Cláudia Botelho and Andreia C. Gomes*


DOI: 10.2174/0929867326666190129142604
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The Glycogen Synthase Kinase-3 in the Regulation of Ion Channels and Cellular Carriers


Mentor Sopjani, Lulzim Millaku, Dashnor Nebija, Merita Emini, Arleta Rifati-Nixha and Miribane Dermaku-Sopjani*


DOI: 10.2174/0929867325666181009122452
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Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone


Cristina Agresti, Rosella Mechelli, Stefania Olla, Caterina Veroni, Cecilia Eleuteri, Giovanni Ristori and Marco Salvetti*


DOI: 10.2174/0929867326666190124122752
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Editorial: Novel Therapeutic Strategies for the Treatment of Chronic Diseases


Gianluca Testa, Fabiana Passaro, Aldo Cinquegrana, Melania Palma, Pasquale Abete and Carlo Gabriele Tocchetti*


DOI: 10.2174/0929867325666190128121918



Endothelium as a Therapeutic Target in Diabetes Mellitus: From Basic Mechanisms to Clinical Practice


Anastasios Tentolouris, Ioanna Eleftheriadou, Evangelia Tzeravini, Dimitrios Tsilingiris, Stavroula A. Paschou, Gerasimos Siasos and Nikolaos Tentolouris*


DOI: 10.2174/0929867326666190119154152
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Ionic Liquids for Topical Delivery in Cancer


Ana Rita Dias, João Costa-Rodrigues, Cátia Teixeira, Paula Gomes, Cristina Prudêncio* and Ricardo Ferraz


DOI: 10.2174/0929867325666181026110227
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Autophagy Modulators and Neuroinflammation


Kyoung Sang Cho, Jang Ho Lee, Jeiwon Cho, Guang-Ho Cha* and Gyun Jee Song*


DOI: 10.2174/0929867325666181031144605
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Graphene and Graphene Oxide Applications for SERS Sensing and Imaging


Anna Jablonska, Alekdandra Jaworska, Mateusz Kasztelan , Sylwia Berbec and Barbara Palys *


DOI: 10.2174/0929867325666181004152247
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The Role of Mitochondria in Systemic Lupus Erythematosus: A Glimpse of Various Pathogenetic Mechanisms


Shi-kun Yang, Hao-ran Zhang, Shu-peng Shi, Ying-qiu Zhu, Na Song, Qing Dai, Wei Zhang, Ming Gui and Hao Zhang*


DOI: 10.2174/0929867326666181126165139
View Abstract View on PubMed







Recent Advances and Challenges of the Drugs Acting on Monoamine Transporters


Weiwei Xue*, Tingting Fu, Guoxun Zheng, Gao Tu, Yang Zhang, Fengyuan Yang, Lin Tao, Lixia Yao and Feng Zhu*


DOI: 10.2174/0929867325666181009123218
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An Update on the Neurochemistry of Essential Tremor


Félix Javier Jiménez-Jiménez *, Hortensia Alonso-Navarro, Elena García-Martín and José A.G. Agúndez


DOI: 10.2174/0929867325666181112094330
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Sam Domains in Multiple Diseases


Marian Vincenzi, Flavia Anna Mercurio and Marilisa Leone*


DOI: 10.2174/0929867325666181009114445
View Abstract View on PubMed


Stimuli-responsive Drug Delivery Nanocarriers in the Treatment of Breast Cancer


Joao A. Oshiro-Junior , Renata Carolina Alves, Gilmar Hanck-Silva , Mariana R. Sato, Camila Rodero, Josimar O. Eloy* and Marlus Chorilli*


DOI: 10.2174/0929867325666181009120610
View Abstract View on PubMed


Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Biologically Active Agents


Maria Assunta Chiacchio , Daniela Iannazzo , Roberto Romeo, Salvatore V. Giofrè and Laura Legnani*


DOI: 10.2174/0929867325666180904125400
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Manipulation of the Immune System for Cancer Defeat: A Focus on the T Cell Inhibitory Checkpoint Molecules


Paolo D’Arrigo, Martina Tufano, Anna Rea, Vincenza Vigorito, Nunzia Novizio, Salvatore Russo, Maria Fiammetta Romano and Simona Romano*


DOI: 10.2174/0929867325666181106114421
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Development of Pin1 Inhibitors and their Potential as Therapeutic Agents


Yusuke Nakatsu, Yasuka Matsunaga, Koji Ueda, Takeshi Yamamotoya, Yuki Inoue, Masa-ki Inoue, Yu Mizuno, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Hisanaka Ito, Takayoshi Okabe and Tomoichiro Asano*


DOI: 10.2174/0929867325666181105120911
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Aptamer-Based Targeted Drug Delivery Systems: Current Potential and Challenges


Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*


DOI: 10.2174/0929867325666181008142831
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Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review


Francisco Javier Alvarez-Martinez, Enrique Barrajon-Catalan*, Jose Antonio Encinar, Juan Carlos Rodriguez-Diaz and Vicente Micol


DOI: 10.2174/0929867325666181008115650
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An Overview of Antiretroviral Agents for Treating HIV Infection in Paediatric Population


Rita Melo, Agostinho Lemos, António J. Preto, Beatriz Bueschell, Pedro Matos-Filipe, Carlos Barreto, José G. Almeida, Rúben D.M. Silva, João D. G. Correia and Irina Moreira*


DOI: 10.2174/0929867325666180904123549
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The Close Interplay of Nitro-Oxidative Stress, Advanced Glycation end Products and Inflammation in Inflammatory Bowel Diseases


Fabiana Andrea Moura, Marília Oliveira Fonseca Goulart*, Amylly Sanuelly da Paz Martins and Samara Bonfim Gomes Campos


DOI: 10.2174/0929867325666180904115633
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Metabolomics of Exhaled Breath Condensate by Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry: A Methodological Approach


Mauro Maniscalco*, Adele Cutignano, Debora Paris, Dominique J. Melck, Antonio Molino, Salvatore Fuschillo and Andrea Motta*


DOI: 10.2174/0929867325666181008122749
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Hydrogel-clay Nanocomposites as Carriers for Controlled Release


Raluca Ianchis, Claudia Ninciuleanu*, Ioana Catalina Gifu, Elvira Alexandrescu, Cristina Lavinia Nistor, Sabina Georgiana Nitu and Cristian Petcu


DOI: 10.2174/0929867325666180831151055
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Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents


Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*


DOI: 10.2174/0929867325666181016163110
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Phenylboronic Acid-polymers for Biomedical Applications


Ji Hyun Ryu, Gyeong Jin Lee, Yu-Ru V Shih, Tae-il Kim* and Shyni Varghese*


DOI: 10.2174/0929867325666181008144436
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Advances in Docking


Vladimir B Sulimov*, Danil C Kutov and Alexey V Sulimov


DOI: 10.2174/0929867325666180904115000
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Lithium – Pharmacological and Toxicological Aspects: The Current State of the Art


Branislava Medić*, Marko Stojanović, Bojan Štimec, Nevena Divac, Katarina Savić Vujović, Radan Stojanović, Mirjana Čolović, Danijela Z. Krstić and Milica Prostran


DOI: 10.2174/0929867325666180904124733
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The Healing Effects of Spices in Chronic Diseases


Danka Bukvicki*, Davide Gottardi, Sahdeo Prasad, Miroslav Novakovic, Petar Marin and Amit Kumar Tyagi


DOI: 10.2174/0929867325666180831145800
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Circulating Biomarkers for Tumor Angiogenesis: Where Are We?


Virginia Di Paolo, Marta Colletti, Valentina Ferruzzi, Ida Russo, Angela Galardi, Iside Alessi , Giuseppe Maria Milano and Angela Di Giannatale*


DOI: 10.2174/0929867325666180821151409
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Xanthine Derivatives as Agents Affecting Non-dopaminergic Neuroprotection in Parkinson`s Disease


Alexandra Kasabova-Angelova, Diana Tzankova, Javor Mitkov, Maya Georgieva, Virginia Tzankova, Alexander Zlatkov and Magdalena Kondeva-Burdina*


DOI: 10.2174/0929867325666180821153316
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Silver Nanomaterials in Contemporary Molecular Physiology Research


Igor Pantic*, David Sarenac, Mila Cetkovic, Milan Milisavljevic, Rastko Rakocevic and Sandor Kasas


DOI: 10.2174/0929867325666180719110432
View Abstract View on PubMed






Latest Updates in Dengue Fever Therapeutics: Natural, Marine and Synthetic Drugs


Samira Hosseini*, Rodrigo B. Munoz-Soto, Jacqueline Oliva-Ramirez, Patricia Vazquez-Villegas, Nasrin Aghamohammadi, Aida Rodriguez-Garcia and Sergio O. Martinez-Chapa


DOI: 10.2174/0929867325666180629124709
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Synthetic Peptide Libraries. From Random Mixtures to In Vivo Testing


Annamaria Sandomenico, Andrea Caporale, Nunzianna Doti, Simon Cross, Gabriele Cruciani, Angela Chambery, Sandro De Falco and Menotti Ruvo*


DOI: 10.2174/0929867325666180716110833
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Impact of Natural Dietary Agents on Multiple Myeloma Prevention and Treatment: Molecular Insights and Potential for Clinical Translation


Lavinia Raimondi, Angela De Luca, Gianluca Giavaresi, Agnese Barone, Pierosandro Tagliaferri, Pierfrancesco Tassone and Nicola Amodio*


DOI: 10.2174/0929867325666180629153141
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The Mechanisms Behind the Biological Activity of Flavonoids


Ana M. Gonzalez-Paramas, Begona Ayuda-Duran, Sofia Martinez, Susana Gonzalez-Manzano and Celestino Santos-Buelga*


DOI: 10.2174/0929867325666180706104829
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The Role of Matrix Gla Protein (MGP) in Vascular Calcification


Geir Bjorklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth


DOI: 10.2174/0929867325666180716104159
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Sitosterolemia: Diagnosis, Metabolic and Hematological Abnormalities, Cardiovascular Disease and Management


Jose Maria Bastida*, Maria Luisa Giros, Rocio Benito, Kamila Janusz, Jesus Maria Hernandez-Rivas and Jose Ramon Gonzalez-Porras


DOI: 10.2174/0929867325666180705145900
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Phytosterols and Inflammation


Gemma Vilahur, Soumaya Ben-Aicha, Elisa Diaz, Lina Badimon and Teresa Padro*


DOI: 10.2174/0929867325666180622151438
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The Role of Diet-Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications


Sara Daniela Gomes, Claudia Suellen Oliveira, Joao Azevedo-Silva, Marta Casanova, Judite Barreto, Helena Pereira, Susana Chaves, Ligia Rodrigues, Margarida Casal, Manuela Corte-Real, Fatima Baltazar and Ana Preto*


DOI: 10.2174/0929867325666180530102050
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Genetically Engineered Elastin-based Biomaterials for Biomedical Applications


Mercedes Santos , Sofia Serrano-Ducar , Juan Gonzalez-Valdivieso , Reinaldo Vallejo, Alessandra Girotti , Purificacion Cuadrado and Francisco Javier Arias*


DOI: 10.2174/0929867325666180508094637
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Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent Update


Faria Sultana, Kesari Lakshmi Manasa, Siddiq Pasha Shaik, Srinivasa Reddy Bonam and Ahmed Kamal*


DOI: 10.2174/0929867325666180530094120
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The LDL-Receptor and its Molecular Properties: From Theory to Novel Biochemical and Pharmacological Approaches in Reducing LDL-cholesterol


Dimitrios Petroglou, Ilias Kanellos, Christos Savopoulos , Georgia Kaiafa*, Anastasios Chrysochoou , Panagiotis Skantzis , Stylianos Daios , Apostolos I. Hatzitolios and Georgios Giannoglou


DOI: 10.2174/0929867325666180604114819
View Abstract View on PubMed




Neoadjuvant Therapy is Essential for Resectable Pancreatic Cancer


Jin-Zhi Xu, Wen-Quan Wang, Shi-Rong Zhang, Hua-Xiang Xu, Chun-Tao Wu, Zi-Hao Qi, He-Li Gao, Shuo Li, Quan-Xing Ni, Xian-Jun Yu and Liang Liu*


DOI: 10.2174/0929867325666180413101722
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Diverse Targeted Approaches to Battle Multidrug Resistance in Cancer


Nagula Shankaraiah*, Shalini Nekkanti , Ojaswitha Ommi and P. S. Soukya Lakshmi


DOI: 10.2174/0929867325666180410110729
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Flavonoids and Platelet-Derived Thrombotic Disorders


Jose J Lopez, Mohammed El haouari, Isaac Jardin, Nieves Alonso, Sergio Regodon, Raquel Diez Bello, Pedro Cosme Redondo and Juan A Rosado*


DOI: 10.2174/0929867325666180417170218
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Acyclovir in the Treatment of Herpes Viruses – A Review


Katarzyna Klysik, Aneta Pietraszek, Anna Karewicz and Maria Nowakowska*


DOI: 10.2174/0929867325666180309105519
View Abstract View on PubMed


The Role of Selenium in Oxidative Stress and in Nonthyroidal Illness Syndrome (NTIS): An Overview


Andrea Silvestrini*, Alvaro Mordente, Giuseppe Martino, Carmine Bruno, Edoardo Vergani, Elisabetta Meucci and Antonio Mancini


DOI: 10.2174/0929867325666180201111159
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Recent Advances in Peptide-Based Approaches for Cancer Treatment


Anne C. Conibear, Alanca Schmid, Meder Kamalov, Christian F.W. Becker and Claudia Bello*


DOI: 10.2174/0929867325666171123204851
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Editor-in-Chief

Atta-ur-Rahman, FRS
(25732 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
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Scopus CiteScore Metrics: 2.63

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