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Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 91st of 298 in

    Biochemistry & Molecular Biology

  • 12th of 61 in

    Chemistry, Medicinal

  • 55th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

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Volume 26

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Number 22



Biography   Open Access



Editorial   Open Access



Review Article

Fine-tuning of microRNAs in Type 2 Diabetes Mellitus

, 26(22): 4102 - 4118

Juan A. Rosado, Raquel Diez-Bello, Ginés M. Salido and Isaac Jardin*


DOI: 10.2174/0929867325666171205163944


Review Article

New Insights into Adipokines as Potential Biomarkers for Type-2 Diabetes Mellitus

, 26(22): 4119 - 4144

Marta Olivera-Santa Catalina, Pedro C. Redondo, Maria P. Granados, Carlos Cantonero , Jose Sanchez-Collado, Letizia Albarran* and Jose J. Lopez


DOI: 10.2174/0929867325666171205162248


Review Article



Review Article

Impact of Diabetes on Cardiac and Vascular Disease: Role of Calcium Signaling

, 26(22): 4166 - 4177

Tarik Smani*, Isabel Gallardo-Castillo, Javier Ávila-Médina, Manuel F. Jimenez-Navarro, Antonio Ordoñez and Abdelkrim Hmadcha


DOI: 10.2174/0929867324666170523140925


Review Article



Review Article

Can Antidiabetic Drugs Improve Male Reproductive (Dys)Function Associated with Diabetes?

, 26(22): 4191 - 4222

R.S. Tavares, S. Escada-Rebelo, M.I. Sousa, A. Silva, J. Ramalho-Santos and S. Amaral*


DOI: 10.2174/0929867325666181101111404


Articles Ahead of Print

The Structures and Bioactivities of Fatty Acid Synthase Inhibitors


Hezhong Jiang , Tian Gan , Jiasui Zhang , Qingyun Ma , Yan Liang* and Youxing Zhao*


DOI: 10.2174/0929867326666190507105022
View Abstract



Redox Regulation in the Base Excision Repair Pathway: Old and New Players as Cancer Therapeutic Targets


Aleksandra Rajapakse, Amila Suraweera, Didier Boucher, Ali Naqi, Kenneth O'Byrne, Derek John Richard and Laura Vanda Croft*


DOI: 10.2174/0929867326666190430092732
View Abstract View on PubMed



Statins in Stroke


Konstantinos Aznaouridis, Constantina Masoura, Charalambos Vlachopoulos and Dimitris Tousoulis


DOI: 10.2174/0929867326666190620104539
View Abstract View on PubMed



Circulating Biomarkers for Response Prediction of Rectal Cancer to Neoadjuvant Chemoradiotherapy


Chiara Bedin*, Sara Crotti, Edoardo D`Angelo, Sara D`Aronco, Salvatore Pucciarelli and Marco Agostini


DOI: 10.2174/0929867326666190507084839
View Abstract View on PubMed




Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets


Melisa Sayé, Chantal Reigada, Lucrecia Gauna, Edward A. Valera-Vera, Claudio A. Pereira* and Mariana R. Miranda


DOI: 10.2174/0929867326666190620094710
View Abstract View on PubMed


Abstracts Ahead of Print

Role of Exosomes in Photodynamic Anticancer Therapy


Yuan Jiang, Chuanshan Xu*, Wingnang Leung*, Mei Lin, Xiaowen Cai, Huanhuan Guo, Jiyong Zhang and Fanwen Yang


DOI: 10.2174/0929867326666190918122221
View Abstract


Copper Concentrations in Breast Cancer: A Systematic Review and Meta-Analysis


Leila Jouybari, Faezeh Kiani, Farhad Islami, Akram Sanagoo*, Fatemeh Sayehmiri, Bozena Hosnedlova, Monica Daniela Doşa, Rene Kizek, Salvatore Chirumbolo and Geir Bjørklund*


DOI: 10.2174/0929867326666190918120209
View Abstract






Trojan Microparticles Potential for Ophthalmic Drug Delivery


Sergio Esteban-Pérez, Irene Bravo-Osuna*, Vanessa Andrés-Guerrero, Irene T. Molina-Martínez and Rocío Herrero-Vanrell


DOI: 10.2174/0929867326666190905150331
View Abstract


The role of the endothelium in premature atherosclerosis: Molecular mechanisms


Michael Spartalis*, Eleftherios Spartalis, Antonios Athanasiou, Stavroula A Paschou, Christos Kontogiannis, Georgios Georgiopoulos, Dimitrios C Iliopoulos and Vassilis Voudris


DOI: 10.2174/0929867326666190911141951
View Abstract



Role of microRNAs in chronic lymphocytic leukemia pathogenesis


Ehsan Javandoost, Ehsan Firoozi Majd, Hosein Rostamian, Mohammad Khakpoor Koosheh and Hamid Reza Mirzaei*


DOI: 10.2174/0929867326666190911114842
View Abstract


Published Contents

Open Access Articles


Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

, 2019; 26(11): 1979 - 1993

Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*





Fighting Type-2 Diabetes: Present and Future Perspectives

, 2019; 26(10): 1891 - 1907

Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*




Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*




Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry

, 2019; 26(1): 216 - 231

Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Renata Wawrzyniak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski*




Carbohydrate Scaffolds for the Study of the Autism-associated Bacterium, Clostridium bolteae

, 2019; 26: 1 - 7 (E-Pub Ahead of Print)

Brittany Pequegnat and Mario Artur Monteiro*




The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease

, 2018; 25(40): 5578 - 5587

Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen*




Mycosporine-Like Amino Acids for Skin Photoprotection

, 2018; 25(40): 5512 - 5527

Karl P. Lawrence, Paul F. Long and Antony R. Young*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25(35): 4638 - 4652

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*




Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

, 2018; 25(35): 4616 - 4637

Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*





Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*





NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment

, 2018; 25(3): 404 - 432

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *





Most Cited Articles


Review Article

Immune checkpoint inhibitors and cardiac toxicity: An emerging issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Review Article

Effects of polyphenolic derivatives on heme oxygenase-system in metabolic dysfunctions

, 1 January 2018; 25(13): 1577-1595.

Valeria Pittala*, Luca Vanella, Loredana Salerno, Giuseppe Romeo, Agostino Marrazzo, Claudia Di Giacomo and Valeria Sorrenti


DOI: 10.2174/0929867324666170616110748


Review Article

Gut-brain axis: Role of lipids in the regulation of inflammation, pain and CNS diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Review Article

Alzheimer's disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126


Review Article

Bisphenol a in reproduction: Epigenetic effects

, 1 January 2018; 25(6): 748-770.

Rosanna Chianese, Jacopo Troisi, Sean Richards, Marika Scafuro , Silvia Fasano, Maurizio Guida , Riccardo Pierantoni and Rosaria Meccariello*


DOI: 10.2174/0929867324666171009121001


Review Article

Carboxylesterase inhibitors: An update

, 2018; 25(14): 1627-1649.

Li-Wei Zou , Qiang Jin, Dan-Dan Wang, Qing-Kai Qian, Da-Cheng Hao, Guang-Bo Ge* and Ling Yang


DOI: 10.2174/0929867325666171204155558


Review Article

Structure, function, involvement in diseases and targeting of 14-3-3 proteins: An Update

, 2018; 25(1): 5-21.

Ylenia Cau, Daniela Valensin, Mattia Mori, Sara Draghi and Maurizio Botta*


DOI: 10.2174/0929867324666170426095015


Review Article

Surface-bioengineered gold nanoparticles for biomedical applications

, 11 January 2018; 25(16): 1920-1944.

Zhicong Miao, Zilin Gao, Ruoxia Chen, Xiaoqing Yu, Zhiqiang Su* and Gang Wei*


DOI: 10.2174/0929867325666180117111404


Review Article

New perspectives on biomedical applications of iron oxide nanoparticles

, 1 January 2018; 25(4): 540-555.

Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de A. Roger and Fabio Vianello*


DOI: 10.2174/0929867324666170616102922


Review Article

Bioactive metabolites from pathogenic and endophytic fung i of forest trees

, 2018; 25(2): 208-252.

Marco Masi, Lucia Maddau, Benedetto Teodoro Linaldeddu, Bruno Scanu , Antonio Evidente and Alessio Cimmino*


DOI: 10.2174/0929867324666170314145159


Review Article

Hydroxypyridinone derivatives: A fascinating class of chelators with therapeutic applications - An update

, 2018; 25(1): 97-112.

Sílvia Chaves, Luca Piemontese, Asha Hiremathad and M. Amélia Santos*


DOI: 10.2174/0929867324666170330092304


Review Article

Metals and parkinson's disease: Mechanisms and biochemical processes

, 2018; 25(19): 2198-2214.

Geir Bjorklund*, Vera Stejskal, Mauricio A. Urbina, Maryam Dadar, Salvatore Chirumbolo and Joachim Mutter


DOI: 10.2174/0929867325666171129124616


Review Article

Ngs technologies as a turning point in rare disease resea rch , diagnosis and treatment

, 1 January 2018; 25(3): 404-432.

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *


DOI: 10.2174/0929867324666170718101946


Review Article

Mycosporine-like amino acids for skin photoprotection

, 2018; 25(40): 5512-5527.

Karl P. Lawrence, Paul F. Long and Antony R. Young*


DOI: 10.2174/0929867324666170529124237



Most Accessed Articles

Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review

, 2017; 24(27): 3002-3009.

Ron Batash , Noam Asna *, Pamela Schaffer, Nicole Francis and Moshe Schaffer


DOI: 10.2174/0929867324666170516123206


Fc-fusion Proteins in Therapy: An Updated View

, 2017; 24(12): 1228-1237.

Reza Jafari, Naime M. Zolbanin, Houshang Rafatpanah, Jafar Majidi and Tohid Kazemi*


DOI: 10.2174/0929867324666170113112759


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017



Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer

, 2017; 24(12): 1170-1185.

Matteo Vergati, Eriseld Krasniqi, Girolamo D. Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni* and Mario Roselli


DOI: 10.2174/0929867324666170116122915


Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Peptide-Drug Conjugate: A Novel Drug Design Approach

, 2017; 24(31): 3373-3396.

Liang Ma, Chao Wang, Zihao He, Biao Cheng, Ling Zheng and Kun Huang*


DOI: 10.2174/0929867324666170404142840



Treatment of Estrogen Receptor-Positive Breast Cancer

, 2013; 20(5): 596-604.

F. Lumachi, A. Brunello, M. Maruzzo, U. Basso and S. M.M. Basso


DOI: 10.2174/092986713804999303


Drugs for Targeted Therapies of Alzheimer’s Disease

, 2019; 26(2): 335-359.

Chit Tam*, Jack Ho Wong*, Tzi Bun Ng*, Stephen Kwok Wing Tsui and Tao Zuo


DOI: 10.2174/0929867325666180430150940




Editor-in-Chief

Atta-ur-Rahman, FRS
(25732 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
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Scopus CiteScore Metrics: 1.72

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