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Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 103th of 293 in

    Biochemistry & Molecular Biology

  • 16th of 59 in

    Chemistry, Medicinal

  • 67th of 261 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

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Volume 26

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Number 2



Biography   Open Access



Editorial   Open Access



Review Article



Review Article

Biosimilars for the Management of Inflammatory Bowel Diseases: Economic Considerations

, 26(2): 259 - 269

Laszlo Gulacsi, Marta Pentek, Fanni Rencz, Valentin Brodszky, Petra Baji, Zsuzsanna Vegh, Krisztina B Gecse, Silvio Danese, Laurent Peyrin-Biroulet and Peter L. Lakatos*


DOI: 10.2174/0929867324666170406112304


Review Article



Review Article



Review Article



Review Article

Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents

, 26(2): 302 - 322

Angelica M. Merlot*, Danuta S. Kalinowski, Zaklina Kovacevic, Patric J. Jansson, Sumit Sahni, Michael L.-H. Huang, Darius J.R. Lane, Hiu Lok and Des R. Richardson*


DOI: 10.2174/0929867324666170705120809


Articles Ahead of Print


Targeting the Ribosome Biogenesis Key Molecule Fibrillarin to Avoid Chemoresistance


Btissame El Hassouni, Dzjemma Sarkisjan, J. Chris Vos, Elisa Giovannetti and Godefridus J Peters*


View Abstract View on PubMed



Therapeutic Prospects in Preeclampsia – A Mini-Review


Nidhi Sharon Das, Shaikali Thameem Dheen, Eng-Ang Ling, Boon Huat Bay and Dinesh Kumar Srinivasan*


View Abstract View on PubMed


B7-H3-targeted Radioimmunotherapy of Human Cancer


Benjamin B. Kasten, Soldano Ferrone, Kurt R. Zinn and Donald J. Buchsbaum*


View Abstract View on PubMed



Pharmacological Management of Chronic Obstructive Lung Disease (COPD). Focus on Mutations


Patrizia Russo, Filippo Lococo, Aliaksei Kisialiou*, Giulia Prinzi, Palma Lamonaca, Vittorio Cardaci and Massimo Fini


View Abstract View on PubMed



Isoliquiritigenin (ISL) and its Formulations: Potential Antitumor Agents


Ting-ting Zhao, Hai-bin Gong, Hai-liang Zhu*, Yu-qing Xu and Hui-min Hu


View Abstract View on PubMed


Metabolomic Biomarkers in Gynecology: A Treasure Path or a False Path?


Igor Govorov , Stanislav Sitkin , Tatyana Pervunina , Alexey Moskvin , Denis Baranenko and Eduard Komlichenko


View Abstract View on PubMed


Abstracts Ahead of Print

Structural basis of drug recognition by human serum albumin


Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi


View Abstract



Nanocrystals as effective delivery systems of poorly water soluble natural molecules


Francesco Lai, Michele Schlich, Rosa Pireddu, Anna Maria Fadda* and Chiara Sinico


View Abstract



Insights into the design of inhibitors of the urease enzyme – a major target for the treatment of Helicobacter pylori infections


Ana Thereza Fiori-Duarte, Ricardo Pereira Rodrigues, Rodrigo Rezende Kitagawa and Daniel Fábio Kawano*


View Abstract


LncRNAs: Potential Novel Prognostic and Diagnostic Biomarkers in Colorectal Cancer


Narges Dastmalchi , Reza Safaralizadeh* and Mirsaed Miri Nargesi


View Abstract



Quaternized Chitosan Nanoparticles in Vaccine Applications


Shuang Yu , Shengnan Hao, Beini Sun , Dongying Zhao , Xingye Yan and Kai Zhao*


View Abstract




Open Access Articles

Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*




Carbohydrate Scaffolds for the Study of the Autism-associated Bacterium, Clostridium bolteae

, 2019; 26: 1 - 7 (E-Pub Ahead of Print)

Brittany Pequegnat and Mario Artur Monteiro*




The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease

, 2018; 25(40): 5578 - 5587

Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen*




Mycosporine-Like Amino Acids for Skin Photoprotection

, 2018; 25(40): 5512 - 5527

Karl P. Lawrence, Paul F. Long and Antony R. Young*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25(35): 4638 - 4652

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*




Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

, 2018; 25(35): 4616 - 4637

Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*




Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*





NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment

, 2018; 25(3): 404 - 432

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *





Lipids as Biomarkers of Cancer and Bacterial Infections

, 2018; 25: 1 - 9 (E-Pub Ahead of Print)

Gerald Larrouy-Maumus *




Immunocontraception: Filamentous Bacteriophage as a Platform for Vaccine Development

, 2017; 24(35): 3907 - 3920

Tatiana I. Samoylova*, Timothy D. Braden, Jennifer A. Spencer and Frank F. Bartol




A Therapeutic Connection between Dietary Phytochemicals and ATP Synthase

, 2017; 24(35): 3894 - 3906

Zulfiqar Ahmad*, Sherif S. Hassan and Sofiya Azim





Major Developments in the Design of Inhibitors along the Kynurenine Pathway

, 2017; 24(23): 2471 - 2495

Kelly R. Jacobs, Gloria Castellano-Gonzalez , Gilles J. Guillemin * and David B. Lovejoy *





Most Cited Articles

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

, 2016; 23(36): 4135-4150.

Hamed Mirzaei, Sara Khataminfar, Saeid Mohammadparast, Soudabeh Shahid Sales, Mina Maftouh, Mohsen Mohammadi, Miganoosh Simonian, Seyed Mohammd Reza Parizadeh, Seyed Mahdi Hassanian and Amir Avan


DOI: 10.2174/0929867323666160818093854





MicroRNAs: Key Players in Microglia and Astrocyte Mediated Inflammation in CNS Pathologies

, 2016; 23(30): 3528-3546.

Aparna Karthikeyan, Radhika Patnala, Shweta P. Jadhav, Ling Eng-Ang and S. Thameem Dheen


DOI: 10.2174/0929867323666160814001040


Adamantane – A Lead Structure for Drugs in Clinical Practice

, 2016; 23(29): 3245-3266.

Katarina Spilovska, Filip Zemek, Jan Korabecny, Eugenie Nepovimova, Ondrej Soukup, Manfred Windisch and Kamil Kuca


DOI: 10.2174/0929867323666160525114026


Application of Mesenchymal Stem Cells in Melanoma: A Potential Therapeutic Strategy for Delivery of Targeted Agents

, 2016; 23(5): 455-463.

Hamed Mirzaei, Amirhossein Sahebkar, Amir Avan, Mahmoud R. Jaafari, Rasoul Salehi, Hossein Salehi, Hossein Baharvand, Abbas Rezaei, Jamshid Hadjati, John M. Pawelek and Hamid R. Mirzaei


DOI: 10.2174/0929867323666151217122033


Morin: A Promising Natural Drug

, 2016; 23(8): 774-791.

Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli


DOI: 10.2174/0929867323666160106150821


Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy

, 2016; 23(30): 3450-3480.

Francesco Moccia, Estella Zuccolo, Valentina Poletto, Ilaria Turin, Germano Guerra, Paolo Pedrazzoli, Vittorio Rosti, Camillo Porta and Daniela Montagna


DOI: 10.2174/0929867323666160607111220




Most Accessed Articles

Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Peptide-Drug Conjugate: A Novel Drug Design Approach

, 2017; 24(31): 3373-3396.

Liang Ma, Chao Wang, Zihao He, Biao Cheng, Ling Zheng and Kun Huang*


DOI: 10.2174/0929867324666170404142840


Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review

, 2017; 24(27): 3002-3009.

Ron Batash , Noam Asna *, Pamela Schaffer, Nicole Francis and Moshe Schaffer


DOI: 10.2174/0929867324666170516123206


Fc-fusion Proteins in Therapy: An Updated View

, 2017; 24(12): 1228-1237.

Reza Jafari, Naime M. Zolbanin, Houshang Rafatpanah, Jafar Majidi and Tohid Kazemi*


DOI: 10.2174/0929867324666170113112759



Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer

, 2017; 24(12): 1170-1185.

Matteo Vergati, Eriseld Krasniqi, Girolamo D. Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni* and Mario Roselli


DOI: 10.2174/0929867324666170116122915



Phosphodiesterase 10 Inhibitors - Novel Perspectives for Psychiatric and Neurodegenerative Drug Discovery

, 2018; 25(29): 3455-3481.

Agnieszka Zagorska*, Anna Partyka, Adam Bucki, Alicja Gawalskax, Anna Czopek and Maciej Pawlowski


DOI: 10.2174/0929867325666180309110629



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