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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

,

Volume 28

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Number 21



Biography   Open Access



Review Article

Targeting the Nucleotide Metabolism Proteins of the NUDIX Family and SAMHD1 in Cancer

, 28(21): 4088 - 4116

Prescillia Forey, Emeline Cros-Perrial, Charles Dumontet and Lars Petter Jordheim*


DOI: 10.2174/0929867328666201125120422


Review Article

A Critical Transcription Factor NF-κB as a Cancer Therapeutic Target and its Inhibitors as Cancer Treatment Options

, 28(21): 4117 - 4132

Mohd Suhail*, Mohammad Tarique, Naoshad Muhammad, Huma Naz, Abdul Hafeez, Torki A. Zughaibi, Mohammad Amjad Kamal and Mohd Rehan*


DOI: 10.2174/0929867327666201111142307


Review Article



Review Article



Review Article

Sigma-2 Receptor as a Potential Drug Target

, 28(21): 4172 - 4189

Ai-Fang Chen, Wen-Hui Ma, Xiao-Yang Xie and Yun-Sheng Huang*


DOI: 10.2174/0929867327666200902172615




Review Article

COVID-19 Related Coagulopathy: What is Known Up to Now

, 28(21): 4207 - 4225

Ana Luísa Batista Pena, Rafael Arantes Oliveira, Renata Gomes Severo and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867327666201005112231


Articles Ahead of Print



miR-30e-5p Regulates Autophagy and Apoptosis by Targeting Beclin1 Involved in Contrast-induced Acute Kidney Injury


Xiaoqin Liu, Qingzhao Li , Lixin Sun, Limei Chen, Yue Li, Beibei Huang, Yunshuang Liu and Chunyang Jiang *


DOI: 10.2174/0929867328666210526125023
View Abstract View on PubMed





Targeting Never-In-Mitosis-A Related Kinase 5 in Cancer: A Review


Margarite D. Matossian*, Carrow I. Wells, William J. Zuercher, Bridgette M. Collins-Burow, David H. Drewry* and Matthew E. Burow*


DOI: 10.2174/0929867328666210322101749
View Abstract View on PubMed


Renin-Angiotensin System in Central Nervous System Diseases and its Interaction with COVID-19


Katharina Lanza, Raphael Dias, Rafaela dos Santos Oliveira, Luís Belotto, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867328666210212101854
View Abstract View on PubMed


Protective Effects of Curcumin Against Lipopolysaccharide-Induced Toxicity


Ali Ganji, Iman Farahani, Amir Mohammad Saeedifar, Ghasem Mosayebi, Ali Ghazavi, Muhammed Majeed, Tannaz Jamialahmadi and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210525124707
View Abstract View on PubMed



Abstracts Ahead of Print



The Role of Tumor Associated Macrophages (TAMs) in Cancer Progression, Chemoresistance, Angiogenesis and Metastasis - Current Status


Siva Dallavalasa, Narasimha M. Beeraka, Chaithanya G. Basavaraju, Subba Rao V. Tulimilli, Surya Prabha Sadhu, Konathala Rajesh, Gjumrakch Aliev and SubbaRao V. Madhunapantula*


DOI: 10.2174/0929867328666210720143721
View Abstract


Natural Products with tandem Anti-inflammatory, Immunomodulatory and Anti-SARS-CoV/2 effects: A Drug Discovery Perspective against SARS-CoV-2


Luana N. O. Leal da Cunha, Tiago Tizziani, Gabriella B. Souza, Monalisa A. Moreira, José S. S. Neto, Carlos V. D. dos Santos, Maryelle G. de Carvalho, Eduardo M. Dalmarco, Leonardo B. Turqueti, Marcus Tullius Scotti, Luciana Scotti, Francisco F. de Assis, Antonio Braga and Louis Pergaud Sandjo*


DOI: 10.2174/0929867328666210726094955
View Abstract


DUXAP8: a promising lncRNA with carcinogenic potential in cancer


Bei Wang, Wen Xu, Yuxuan Cai, Jinlan Chen, Chong Guo, Gang Zhou* and Chengfu Yuan*


DOI: 10.2174/0929867328666210726092020
View Abstract


Colorectal Serrated Lesions: a Current View on Clinical, Morphological, Molecular, and Genetic Diagnostic Criteria


Liudmila M. Mikhaleva*, Rositsa A. Vandysheva, Konstantin Yu. Midiber, Olesya A. Vasyukova, Valentina V. Pechnikova, Olga I. Patsap, Ozal Beylerli, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev


DOI: 10.2174/0929867328666210715125428
View Abstract



The role of PCSK9 in infectious diseases


Laura Magnasco, Chiara Sepulcri, Roberta Maria Antonello , Stefano Di Bella, Laura Labate , Roberto Luzzati , Daniele Roberto Giacobbe* and Matteo Bassetti


DOI: 10.2174/0929867328666210714160343
View Abstract


Environmental Factors Modifying HDL Functionality


Constantine E. Kosmas, Andreas Sourlas, Eliscer Guzman and Christina E. Kostara*


DOI: 10.2174/0929867328666210714155422
View Abstract



Published Contents

Open Access Articles

A Novel Dicationic Boron Dipyrromethene-based Photosensitizer for Antimicrobial Photodynamic Therapy against Methicillin-Resistant Staphylococcus aureus

, 2021; 28(21): 4283 - 4294

Priyanga Dharmaratne, Ligang Yu, Roy Chi-Hang Wong, Ben Chun-Lap Chan, Kit-Man Lau, Baiyan Wang, Clara Bik San Lau, Kwok-Pui Fung, Dennis Kee-Pui Ng and Margaret Ip*







Role of Alpha-Fetoprotein in Hepatocellular Carcinoma Drug Resistance

, 2021; 28(6): 1126 - 1142

Wei Li, Kun Liu, Yi Chen, Mingyue Zhu* and Mengsen Li*




Deep Learning in the Quest for Compound Nomination for Fighting COVID-19

, 2021; 28: 1 - 32 (E-Pub Ahead of Print)

Maria Mernea, Eliza. C. Martin, Andrei-José Petrescu* and Speranta Avram*




Evidence of Protein Binding by a Nucleopeptide Based on a Thyminedecorated L-Diaminopropanoic Acid through CD and In Silico Studies

, 2021; 28: 1 - 12 (E-Pub Ahead of Print)

Valentina Roviello, Domenica Musumeci, Andriy Mokhir and Giovanni N. Roviello*




Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

, 2020; 27(42): 7234 - 7255

Soraia Fernandes*, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri and Giancarlo Forte*





Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2020; 27(37): 6356 - 6372

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*










Most Cited Articles


Review Article

Role of ox-LDL and LOX-1 in atherogenesis

, 2019; 26(9): 1693-1700.

Ajoe John Kattoor, Sri Harsha Kanuri and Jawahar L. Mehta*


DOI: 10.2174/0929867325666180508100950



Review Article

Targeting cxcl12/cxcr4 axis in tumor immunotherapy

, 2019; 26(17): 3026-3041.

Weiqiang Zhou, Shanchun Guo*, Mingli Liu, Matthew E. Burow and Guangdi Wang*


DOI: 10.2174/0929867324666170830111531


Review Article

Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases

, 2019; 26(18): 3225-3241.

Miguel D. Ferrer, Carla Busquets-Cortés, Xavier Capó, Silvia Tejada, Josep A. Tur, Antoni Pons and Antoni Sureda*


DOI: 10.2174/0929867325666180514112124


General Review Article

Homocysteine and hyperhomocysteinaemia

, 2019; 26(16): 2948-2961.

Bozidarka L. Zaric*, Milan Obradovic, Vladan Bajic , Mohamed A. Haidara , Milos Jovanovic and Esma R. Isenovic*


DOI: 10.2174/0929867325666180313105949


Review Article

Plant-derived products as antibacterial and antifungal agents in human health care

, 2019; 26(29): 5501-5541.

Ladislav Kokoska*, Pavel Kloucek , Olga Leuner* and Pavel Novy


DOI: 10.2174/0929867325666180831144344


Review Article

ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma

, 2019; 26(7): 1224-1250.

María Paula Ceballos, Juan Pablo Rigalli, Lucila Inés Ceré, Mariana Semeniuk, Viviana Alicia Catania and María Laura Ruiz*


DOI: 10.2174/0929867325666180105103637


Review Article

Role of autophagy in Parkinson’s disease

, 2019; 26(20): 3702-3718.

Silvia Cerri and Fabio Blandini*


DOI: 10.2174/0929867325666180226094351


Review Article

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

, 2020; 27(37): 6356-6372.

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*


DOI: 10.2174/0929867326666190730113123



Review Article

Electronic noses in medical diagnostics

, 2019; 26(1): 197-215.

Wojciech Wojnowski*, Tomasz Dymerski*, Jacek Gębicki and Jacek Namieśnik


DOI: 10.2174/0929867324666171004164636


General Review Article

Aptamer-based targeted drug delivery systems: Current potential and challenges

, 2020; 27(13): 2189-2219.

Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*


DOI: 10.2174/0929867325666181008142831


Review Article

Immune checkpoint inhibitors: Basics and challenges

, 2019; 26(17): 3009-3025.

Bin Li*, Ho Lam Chan and Pingping Chen*


DOI: 10.2174/0929867324666170804143706


Review Article

Applications of cellulose-based materials in sustained drug delivery systems

, 2019; 26(14): 2485-2501.

Bo Sun, Min Zhang, Jing Shen, Zhibin He, Pedram Fatehi* and Yonghao Ni


DOI: 10.2174/0929867324666170705143308



Most Accessed Articles

Targeting the Nucleotide Metabolism Proteins of the NUDIX Family and SAMHD1 in Cancer

, 2021; 28(21): 4088-4116.

Prescillia Forey, Emeline Cros-Perrial, Charles Dumontet and Lars Petter Jordheim*


DOI: 10.2174/0929867328666201125120422


Drug Repurposing: Promises of Edaravone Target Drug in Traumatic Brain Injury

, 2021; 28(12): 2369-2391.

Zaynab Shakkour, Hawraa Issa, Helene Ismail, Ohanes Ashekyan, Karl John Habashy, Leila Nasrallah, Hussam Jourdi, Eva Hamade, Stefania Mondello, Mirna Sabra*, Kazem Zibara* and Firas Kobeissy*


DOI: 10.2174/0929867327666200812221022


Machine Learning-Based Scoring Functions, Development and Applications with SAnDReS

, 2021; 28(9): 1746-1756.

Gabriela Bitencourt-Ferreira, Camila Rizzotto and Walter Filgueira de Azevedo Junior*


DOI: 10.2174/0929867327666200515101820


Advances in Sickle Cell Disease Treatments

, 2021; 28(10): 2008-2032.

Aline Renata Pavan and Jean Leandro dos Santos*


DOI: 10.2174/0929867327666200610175400


New Perspectives in the Pharmacological Potential of Naringin in Medicine

, 2021; 28(10): 1987-2007.

María Angélica Rivoira, Valeria Rodriguez, Germán Talamoni and Nori Tolosa de Talamoni*


DOI: 10.2174/0929867327666200604171351


Astroglial Connexins in Neurological and Neuropsychological Disorders and Radiation Exposure

, 2021; 28(10): 1970-1986.

Yuan Duo Liu, Ge Tang, Feng Qian, Lian Liu*, Jiang Rong Huang* and Feng Ru Tang*


DOI: 10.2174/0929867327666200610175037


Convolutional Neural Network-based Virtual Screening

, 2021; 28(10): 2033-2047.

Wenying Shan, Xuanyi Li, Hequan Yao and Kejiang Lin*


DOI: 10.2174/0929867327666200526142958


The Correlation between Lipid Metabolism Disorders and Prostate Cancer

, 2021; 28(10): 2048-2061.

Justyna Dłubek, Jacek Rysz, Zbigniew Jabłonowski, Anna Gluba-Brzózka* and Beata Franczyk


DOI: 10.2174/0929867327666200806103744



A Critical Transcription Factor NF-κB as a Cancer Therapeutic Target and its Inhibitors as Cancer Treatment Options

, 2021; 28(21): 4117-4132.

Mohd Suhail*, Mohammad Tarique, Naoshad Muhammad, Huma Naz, Abdul Hafeez, Torki A. Zughaibi, Mohammad Amjad Kamal and Mohd Rehan*


DOI: 10.2174/0929867327666201111142307



Sigma-2 Receptor as a Potential Drug Target

, 2021; 28(21): 4172-4189.

Ai-Fang Chen, Wen-Hui Ma, Xiao-Yang Xie and Yun-Sheng Huang*


DOI: 10.2174/0929867327666200902172615







Editor-in-Chief

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

graphic
Prof. John Gurdon
(UK)

graphic
Prof. Jean-Marie Lehn
(France)

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Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.

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