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Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 91st of 298 in

    Biochemistry & Molecular Biology

  • 12th of 61 in

    Chemistry, Medicinal

  • 55th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

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Volume 26

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Number 30



Biography   Open Access



Review Article

Research Progress on Brucellosis

, 26(30): 5598 - 5608

Yuming Deng, Xinyue Liu, Kaifang Duan and Qisheng Peng*


DOI: 10.2174/0929867325666180510125009


Review Article



Review Article

A Systematic Review on Donepezil-based Derivatives as Potential Cholinesterase Inhibitors for Alzheimer’s Disease

, 26(30): 5625 - 5648

Jan Korabecny , Katarina Spilovska, Eva Mezeiova , Ondrej Benek , Radomir Juza , Daniel Kaping and Ondrej Soukup*


DOI: 10.2174/0929867325666180517094023


Review Article



Review Article



Review Article



Review Article



Current Medicinal Chemistry, Volume 26 (2019) - Number 34


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 26 (2019) - Number 33


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 26 (2019) - Number 32


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 26 (2019) - Number 31


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids


Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo


DOI: 10.2174/0929867326666191029112626
View Abstract View on PubMed


In Silico Drug Repositioning for Chagas Disease


Carolina L. Bellera, Lucas N. Alberca, María L. Sbaraglini and Alan Talevi*


DOI: 10.2174/0929867326666191016114839
View Abstract View on PubMed



The Beneficial Actions of SGLT-2 Inhibitors Beyond the Management of Hyperglycemia


Charalampos Loutradis, Eirini Papadopoulou, Elena Angeloudi, Asterios Karagiannis and Pantelis Sarafidis*


DOI: 10.2174/0929867326666191029111713
View Abstract View on PubMed


Joint Application of Magnetic Resonance Imaging and Biochemical Biomarkers in Diagnosis of Multiple Sclerosis


Fatemeh Momeni, Amir Ghaemmaghami, Majid Nejati, Mohammad Hossein Pourhanifeh, Laleh Shiri Sichani, Omid Reza Tamtaji, Mohammad Momeni, Alireza Khosravi*, Masoud Etemadifar* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191014162713
View Abstract View on PubMed



Coronary Artery Disease and Endothelial Dysfunction: Novel Diagnostic and Therapeutic Approaches


Evangelos Oikonomou*, Gerasimos Siasos, Vasiliki Tsigkou, Evanthia Bletsa, Maria-Evi Panoilia, Iris Niovi Oikonomou, Ilias Sinanidis, Marianna Spinou, Angeliki Papastavrou, Georgios Kokosias, Marina Zaromitidou, Panagiota Stampouloglou, Michael Spartalis, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitris Tousoulis


DOI: 10.2174/0929867326666190830103219
View Abstract View on PubMed



Recent Theoretical Studies Concerning Important Tropical Infections


Alex France Messias Monteiro, Jessika de Oliveira Viana*, Francisco Jaime BM Junior, Hamiilton M Ishiki, Ernestine Nkwengoua Tchouboun, Rodrigo Santos de Araújo, Marcus Tullius Scotti and Luciana Scotti


DOI: 10.2174/0929867326666190711121418
View Abstract View on PubMed


Anti-VEGF Treatment and Response in Age-related Macular Degeneration: Disease´s Susceptibility, Pharmacogenetics and Pharmacokinetics


Olalla Maroñas , Laura García-Quintanilla*, Andrea Luaces-Rodríguez, Anxo Fernández-Ferreiro, Ana Latorre-Pellicer, Maximino José Abraldes, María Jesús Lamas and Ángel Carracedo *


DOI: 10.2174/0929867326666190711105325
View Abstract View on PubMed


Abstracts Ahead of Print


Electrochemical-Based Biosensors: New diagnosis Platforms for Cardiovascular Disease


Fatemeh Yousefi, Ahmad Movahedpour, Zahra Shabaninejad, Younes Ghasemi, Shahram Rabbani, Ali Sobnani-Nasab, Soheila Mohammadi, Behzad Hajimoradi, Samaneh Rezaei, Amir Savardashtaki*, Majid Mazoochi* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191024114207
View Abstract


Drug leads derived from Japanese marine organisms


Daisuke Uemura*, Yoshinori Kawazoe, Toshiyasu Inuzuka, Yuki Itakura, Chiari Kawamata and Takahiro Abe*


DOI: 10.2174/0929867326666191022125851
View Abstract


The predictive role for ST2 in patients with acute coronary syndromes and heart failure.


Vasiliki Tsigkou*, Gerasimos Siasos*, Evanthia Bletsa, Maria- Evi Panoilia, Angeliki Papastavrou, Georgios Kokosias, Evangelos Oikonomou, Nikolaos Papageorgiou, Marina Zaromitidou, Georgios Marinos, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitris Tousoulis


DOI: 10.2174/0929867326666191016121630
View Abstract


Natural Hydrogels Applied in Photodynamic Therapy


Zhipan feng, Shiying lLn, Andrew McDonagh* and Chen Yu


DOI: 10.2174/0929867326666191016112828
View Abstract



Tubulin inhibitors binding to colchicine-site: A Review from 2015 to 2019


Lin-Ying Xia, Ya-Liang Zhang, Rong Yang, Zhong-Chang Wang, Ya-Dong Lu*, Bao-Zhong Wang* and Hai-Liang Zhu


DOI: 10.2174/0929867326666191003154051
View Abstract



Endothelium in aortic aneurysm disease: New insights


Eleftherios Spartalis*, Michael Spartalis, Antonios Athanasiou, Stavroula A Paschou, Nikolaos Patelis, Vassilis Voudris and Dimitrios C. Iliopoulos


DOI: 10.2174/0929867326666190923151959
View Abstract



Published Contents

Open Access Articles



Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

, 2019; 26(11): 1979 - 1993

Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*





Fighting Type-2 Diabetes: Present and Future Perspectives

, 2019; 26(10): 1891 - 1907

Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*




Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*




Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry

, 2019; 26(1): 216 - 231

Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Renata Wawrzyniak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski*





Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2019; 26: 1 - 16 (E-Pub Ahead of Print)

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*




The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease

, 2018; 25(40): 5578 - 5587

Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen*




Mycosporine-Like Amino Acids for Skin Photoprotection

, 2018; 25(40): 5512 - 5527

Karl P. Lawrence, Paul F. Long and Antony R. Young*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25(35): 4638 - 4652

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*




Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

, 2018; 25(35): 4616 - 4637

Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*





Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*





Most Cited Articles


Review Article

Effects of polyphenolic derivatives on heme oxygenase-system in metabolic dysfunctions

, 1 January 2018; 25(13): 1577-1595.

Valeria Pittala*, Luca Vanella, Loredana Salerno, Giuseppe Romeo, Agostino Marrazzo, Claudia Di Giacomo and Valeria Sorrenti


DOI: 10.2174/0929867324666170616110748


Review Article

Alzheimer's disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126


Review Article

Immune checkpoint inhibitors and cardiac toxicity: An emerging issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Review Article

Gut-brain axis: Role of lipids in the regulation of inflammation, pain and CNS diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Review Article

Bisphenol a in reproduction: Epigenetic effects

, 1 January 2018; 25(6): 748-770.

Rosanna Chianese, Jacopo Troisi, Sean Richards, Marika Scafuro , Silvia Fasano, Maurizio Guida , Riccardo Pierantoni and Rosaria Meccariello*


DOI: 10.2174/0929867324666171009121001


Review Article

New perspectives on biomedical applications of iron oxide nanoparticles

, 1 January 2018; 25(4): 540-555.

Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de A. Roger and Fabio Vianello*


DOI: 10.2174/0929867324666170616102922


Review Article

Carboxylesterase inhibitors: An update

, 2018; 25(14): 1627-1649.

Li-Wei Zou , Qiang Jin, Dan-Dan Wang, Qing-Kai Qian, Da-Cheng Hao, Guang-Bo Ge* and Ling Yang


DOI: 10.2174/0929867325666171204155558


Review Article

Structure, function, involvement in diseases and targeting of 14-3-3 proteins: An Update

, 2018; 25(1): 5-21.

Ylenia Cau, Daniela Valensin, Mattia Mori, Sara Draghi and Maurizio Botta*


DOI: 10.2174/0929867324666170426095015


Review Article

Surface-bioengineered gold nanoparticles for biomedical applications

, 11 January 2018; 25(16): 1920-1944.

Zhicong Miao, Zilin Gao, Ruoxia Chen, Xiaoqing Yu, Zhiqiang Su* and Gang Wei*


DOI: 10.2174/0929867325666180117111404


Review Article

Metals and parkinson's disease: Mechanisms and biochemical processes

, 2018; 25(19): 2198-2214.

Geir Bjorklund*, Vera Stejskal, Mauricio A. Urbina, Maryam Dadar, Salvatore Chirumbolo and Joachim Mutter


DOI: 10.2174/0929867325666171129124616



Review Article

Bioactive metabolites from pathogenic and endophytic fung i of forest trees

, 2018; 25(2): 208-252.

Marco Masi, Lucia Maddau, Benedetto Teodoro Linaldeddu, Bruno Scanu , Antonio Evidente and Alessio Cimmino*


DOI: 10.2174/0929867324666170314145159


Review Article

Hydroxypyridinone derivatives: A fascinating class of chelators with therapeutic applications - An update

, 2018; 25(1): 97-112.

Sílvia Chaves, Luca Piemontese, Asha Hiremathad and M. Amélia Santos*


DOI: 10.2174/0929867324666170330092304


Review Article

Inorganic nanoparticles for cancer therapy: A transition from lab to clinic

, 2018; 25(34): 4269-4303.

Samer Bayda, Mohamad Hadla, Stefano Palazzolo, Pietro Riello, Giuseppe Corona, Giuseppe Toffoli and Flavio Rizzolio*


DOI: 10.2174/0929867325666171229141156



Most Accessed Articles

Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review

, 2017; 24(27): 3002-3009.

Ron Batash , Noam Asna *, Pamela Schaffer, Nicole Francis and Moshe Schaffer


DOI: 10.2174/0929867324666170516123206


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Fc-fusion Proteins in Therapy: An Updated View

, 2017; 24(12): 1228-1237.

Reza Jafari, Naime M. Zolbanin, Houshang Rafatpanah, Jafar Majidi and Tohid Kazemi*


DOI: 10.2174/0929867324666170113112759


Peptide-Drug Conjugate: A Novel Drug Design Approach

, 2017; 24(31): 3373-3396.

Liang Ma, Chao Wang, Zihao He, Biao Cheng, Ling Zheng and Kun Huang*


DOI: 10.2174/0929867324666170404142840


Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer

, 2017; 24(12): 1170-1185.

Matteo Vergati, Eriseld Krasniqi, Girolamo D. Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni* and Mario Roselli


DOI: 10.2174/0929867324666170116122915


An Update on JAK Inhibitors

, 2019; 26(10): 1806-1832.

Francesca Musumeci*, Chiara Greco, Ilaria Giacchello, Anna Lucia Fallacara, Munjed M. Ibrahim, Giancarlo Grossi, Chiara Brullo and Silvia Schenone


DOI: 10.2174/0929867325666180327093502


Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126



Lipoproteins in Atherosclerosis Process

, 2019; 26(9): 1525-1543.

Valentina Arnao, Antonino Tuttolomondo*, Mario Daidone and Antonio Pinto


DOI: 10.2174/0929867326666190516103953




Editor-in-Chief

Atta-ur-Rahman, FRS
(25732 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
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Scopus CiteScore Metrics: 2.63

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