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Current Gene Therapy

Volume 19, 6 Issues, 2019
ISSN: 1566-5232 (Print)
ISSN: 1875-5631 (Online)
This journal supports open access

Ranking and Category

  • 108th of 174 in

    Genetics & Heredity

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Aims & Scope

Current Gene Therapy is a bi-monthly peer-reviewed journal aimed at academic and industrial scientists with an interest in major topics concerning basic research and clinical applications of gene and cell therapy of diseases. Cell therapy manuscripts can also include application in diseases when cells have been genetically modified. Current Gene Therapy publishes full-length/mini reviews and original research on the latest developments in gene transfer and gene expression analysis, vector development, cellular genetic engineering, animal models and human clinical applications of gene and cell therapy for the treatment of diseases.

Current Gene Therapy publishes reviews and original research containing experimental data on gene and cell therapy. The journal also includes manuscripts on technological advances, ethical and regulatory considerations of gene and cell therapy. Reviews should provide the reader with a comprehensive assessment of any area of experimental biology applied to molecular medicine that is not only of significance within a particular field of gene therapy and cell therapy but also of interest to investigators in other fields. Authors are encouraged to provide their own assessment and vision for future advances. Reviews are also welcome on late breaking discoveries on which substantial literature has not yet been amassed. Such reviews provide a forum for sharply focused topics of recent experimental investigations in gene therapy primarily to make these results accessible to both clinical and basic researchers. Manuscripts containing experimental data should be original data, not previously published.

Current Gene Therapy

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Volume 19

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Number 1



Preface   Open Access

Preface

, 19(1): 1

Lung-Ji Chang and Alfred S. Lewin


DOI: 10.2174/156652321901190502112219


Biography   Open Access



Perspective   Open Access

Gene Therapy of Anderson-Fabry Disease

, 19(1): 3 - 5

Antonino Tuttolomondo, Irene Simonetta* and Antonio Pinto


DOI: 10.2174/1566523219999190415160632


Editorial   Open Access



Review Article



Review Article



Research Article



Research Article   Open Access

Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 19(1): 40 - 53

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*


DOI: 10.2174/1566523218666181116093857


Articles Ahead of Print




Understanding Gene Therapy in Acute Respiratory Distress Syndrome


Xue-Peng Zhang, Wei-Tao Zhang, Yue Qiu, Min-Jie Ju, Guo-Wei Tu* and Zhe Luo*


DOI: 10.2174/1566523219666190702154817
View Abstract



Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy


Angela L. McCall*, Sylvia G. Stankov, Gabrielle Cowen, Denise Cloutier, Zizhao Zhang, Lin Yang, Nathalie Clement, Darin J. Falk and Barry J. Byrne*


DOI: 10.2174/1566523219666190621113807
View Abstract View on PubMed




Correlation between MDSC and Immune Tolerance in Transplantation: Cytokines, Pathways and Cell-cell Interaction


Tianying Yang, Jiawei Li, Ruimin Li, Chunchen Yang, Weitao Zhang, Yue Qiu, Cheng Yang* and Ruiming Rong*


DOI: 10.2174/1566523219666190618093707
View Abstract



Published Contents

Editor's Choice


Neuroprotection by Human Dental Pulp Mesenchymal Stem Cells: From Billions to Nano

, 2018; 18(5): 307 - 323

Chaitra Venugopal, Shobha K, Kiranmai S. Rai, Venkata Bharatkumar Pinnelli, Bindu M. Kutty and Anandh Dhanushkodi*


DOI: 10.2174/1566523218666180913152615




Gene Therapy to Enhance Bone and Cartilage Repair in Orthopaedic Surgery

, 2018; 18(3): 154 - 170

Sofia Bougioukli, Christopher H. Evans, Ram K. Alluri, Steven C. Ghivizzani and Jay R. Lieberman*


DOI: 10.2174/1566523218666180410152842






A New Era for Hemoglobinopathies: More Than One Curative Option

, 2017; 17(5): 364 - 378

Nikoletta Psatha, Penelope-Georgia Papayanni and Evangelia Yannaki*


DOI: 10.2174/1566523218666180119123655





Open Access Articles

Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2019; 19(1): 40 - 53

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*




Three Cases of Leber’s Hereditary Optic Neuropathy with Rapid Increase in Visual Acuity After Gene Therapy

, 2019; 19: 1 - 5 (E-Pub Ahead of Print)

Yong Zhang, Jia-jia Yuan, Hong-li Liu, Zhen Tian, Si-wei Liu and Bin Li*




Clinical Observation of Patients with Leber’s Hereditary Optic Neuropathy Before Gene Therapy

, 2018; 18(6): 386 - 392

Jiajia Yuan, Yong Zhang, Hongli Liu, Zhen Tian, Xin Li, Yichen Zheng, Qin Gao, Lin Song, Xiao Xiao, Jian Sun, Zhitao Wang and Bin Li*




Clinical-Grade Oncolytic Adenovirus Purification Using Polysorbate 20 as an Alternative for Cell Lysis

, 2018; 18(6): 366 - 374

Mafalda G. Moleirinho, Sara Rosa, Manuel J.T. Carrondo*, Ricardo J.S. Silva, Åsa Hagner-McWhirter, Gustaf Ahlén, Mats Lundgren, Paula M. Alves and Cristina Peixoto




Emerging Therapeutic Approaches for Diamond Blackfan Anemia

, 2018; 18(6): 327 - 335

Anna Aspesi*, Chiara Borsotti and Antonia Follenzi*




EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275 - 285

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*




Human Disease System Biology

, 2018; 18(5): 255 - 256

Liang Cheng and Yang Hu




Oncolytic Virotherapy for Breast Cancer Treatment

, 2018; 18(4): 192 - 205

Samia M. O`Bryan and J. Michael Mathis*




Genetics and Therapies for GM2 Gangliosidosis

, 2018; 18(2): 68 - 89

Maria Begona Cachon-Gonzalez*, Eva Zaccariotto and Timothy Martin Cox





The Progress of Gene Therapy for Leber's Optic Hereditary Neuropathy

, 2017; 17(4): 320 - 326

Yong Zhang, Zhen Tian, Jiajia Yuan, Chang Liu, Hong li Liu, Si Qi Ma and Bin Li*





Tet-On Systems For Doxycycline-inducible Gene Expression

, 2016; 16(3): 156 - 167

Atze T. Das, Liliane Tenenbaum and Ben Berkhout




Gene Electrotransfer: A Mechanistic Perspective

, 2016; 16(2): 98 - 129

Christelle Rosazza, Sasa Haberl Meglic, Andreas Zumbusch, Marie-Pierre Rols and Damijan Miklavcic




Building A New Treatment For Heart Failure-Transplantation of Induced Pluripotent Stem Cell-derived Cells into the Heart

, 2016; 16(1): 5 - 13

Shigeru Miyagawa, Satsuki Fukushima, Yukiko Imanishi, Takuji Kawamura, Noriko Mochizuki- Oda, Shigeo Masuda and Yoshiki Sawa





Most Cited Articles

Research Article

Transplantation of BDNF gene recombinant mesenchymal stem cells and adhesive peptide-modified hydrogel scaffold for spinal cord repair

, 2018; 18(1): 29-39.

Li-Ming Li, Ling-Ling Huang, Xin-Chi Jiang, Jia-Chen Chen, Hong-Wei OuYang and Jian-Qing Gao *


DOI: 10.2174/1566523218666180413150023



Review Article

Mir-7 replacement therapy in parkinson’s disease

, 2018; 18(3): 143-153.

Ricardo Titze-de-Almeida* and Simoneide Souza Titze-de-Almeida*


DOI: 10.2174/1566523218666180430121323


Review Article

Gene therapy to enhance bone and cartilage repair in orthopaedic surgery

, 2018; 18(3): 154-170.

Sofia Bougioukli, Christopher H. Evans, Ram K. Alluri, Steven C. Ghivizzani and Jay R. Lieberman*


DOI: 10.2174/1566523218666180410152842


Review Article

Nonviral delivery systems for cancer gene therapy: Strategies and challenges

, 2018; 18(1): 3-20.

Gayong Shim*, Dongyoon Kim, Quoc-Viet Le, Gyu Thae Park, Taekhyun Kwon and Yu-Kyoung Oh*


DOI: 10.2174/1566523218666180119121949


Review Article

Genetics and gene therapy of anderson-fabry disease

, 2018; 18(2): 96-106.

Irene Simonetta*, Antonino Tuttolomondo, Tiziana Di Chiara, Salvatore Miceli, Danai Vogiatzis, Francesca Corpora and Antonio Pinto


DOI: 10.2174/1566523218666180404161315


Review Article

Genetics and therapies for GM2 gangliosidosis

, 2018; 18(2): 68-89.

Maria Begona Cachon-Gonzalez*, Eva Zaccariotto and Timothy Martin Cox


DOI: 10.2174/1566523218666180404162622


Research Article

Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2019; 19(1): 40-53.

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*


DOI: 10.2174/1566523218666181116093857



Research Article

A brief survey of machine learning application in cancerlectin identification

, 2018; 18(5): 31-39.

Md. Thoufic A. Azad, Umme Qulsum and Toshifumi Tsukahara*


DOI: 10.2174/1573408014666180626154016


Research Article

Ezh2 rip-seq identifies tissue-specific long non-coding rnas

, 2018; 18(5): 31-39.

Md. Thoufic A. Azad, Umme Qulsum and Toshifumi Tsukahara*


DOI: 10.2174/1573408014666180621094828


Research Article

Deep Forest-based Prediction of Protein Subcellular Localization

, 2018; 18(5): 268-274.

Lingling Zhao*, Junjie Wang, Mahieddine Mohammed Nabil and Jun Zhang*


DOI: 10.2174/1566523218666180913110949


General Research Article

Neuroprotection by Human Dental Pulp Mesenchymal Stem Cells: From Billions to Nano

, 2018; 18(5): 307-323.

Chaitra Venugopal, Shobha K, Kiranmai S. Rai, Venkata Bharatkumar Pinnelli, Bindu M. Kutty and Anandh Dhanushkodi*


DOI: 10.2174/1566523218666180913152615


Research Article

Identifying Keystone Species in the Microbial Community Based on Cross- Sectional Data

, 2018; 18(5): 296-306.

Min Li, Jun Zhang, Bo Wu, Zhongliang Zhou and Yongdong Xu*


DOI: 10.2174/1566523218666181008155734


Research Article

EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275-285.

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*


DOI: 10.2174/1566523218666181008125010



Most Accessed Articles


Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2019; 19(1): 40-53.

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*


DOI: 10.2174/1566523218666181116093857


Gene Therapy of Anderson-Fabry Disease

, 2019; 19(1): 3-5.

Antonino Tuttolomondo, Irene Simonetta* and Antonio Pinto


DOI: 10.2174/1566523219999190415160632







Design of Artificial Immunogens Containing Melanoma-associated T-cell Epitopes

, 2018; 18(6): 375-385.

E.A. Borobova*, D.V. Antonets, E.V. Starostina, L.I. Karpenko, A.A. Ilyichev and S.I. Bazhan


DOI: 10.2174/1566523218666181113112829





Editor-in-Chief

Lung-Ji Chang
University of Florida
Gainesville, FL
USA

Biography View Full Editorial Board

Journal History

Current Gene Therapy Journal was launched in 2001. Dr. Lung-Ji Chang serves as the Editor-in-Chief of the journal.
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